Detailed information
Bioinformatically predicted
Overview
| Name | comGH | Type | Machinery gene |
| Locus tag | SPYM18_RS00680 | Genome accession | NC_003485 |
| Coordinates | 105866..106819 (+) | Length | 317 a.a. |
| NCBI ID | WP_002987790.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes MGAS8232 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 100866..111819
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SPYM18_RS00640 (spyM18_0101) | - | 101694..102059 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| SPYM18_RS00645 (spyM18_0102) | comGA | 102151..103089 (+) | 939 | WP_002986557.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| SPYM18_RS00650 (spyM18_0103) | comGB | 103025..104059 (+) | 1035 | WP_226976794.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| SPYM18_RS00655 (spyM18_0105) | comGC | 104061..104387 (+) | 327 | WP_002986552.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| SPYM18_RS00660 (spyM18_0106) | comGD | 104362..104790 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | Machinery gene |
| SPYM18_RS00665 (spyM18_0107) | comGE | 104747..105031 (+) | 285 | WP_002987779.1 | competence type IV pilus minor pilin ComGE | Machinery gene |
| SPYM18_RS00670 (spyM18_0108) | comGF | 105024..105458 (+) | 435 | WP_002986542.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| SPYM18_RS00675 (spyM18_0109) | comGG | 105442..105768 (+) | 327 | WP_002986539.1 | competence type IV pilus minor pilin ComGG | - |
| SPYM18_RS00680 (spyM18_0110) | comGH | 105866..106819 (+) | 954 | WP_002987790.1 | class I SAM-dependent methyltransferase | Machinery gene |
| SPYM18_RS00685 (spyM18_0111) | - | 106878..108074 (+) | 1197 | WP_002986533.1 | acetate kinase | - |
| SPYM18_RS00690 (spyM18_0112) | - | 108261..108569 (+) | 309 | WP_011017251.1 | hypothetical protein | - |
| SPYM18_RS00695 (spyM18_0113) | proC | 108652..109422 (-) | 771 | WP_002986527.1 | pyrroline-5-carboxylate reductase | - |
| SPYM18_RS00700 (spyM18_0115) | pepA | 109470..110537 (-) | 1068 | WP_011017252.1 | glutamyl aminopeptidase | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35985.08 Da Isoelectric Point: 4.7205
>NTDB_id=22541 SPYM18_RS00680 WP_002987790.1 105866..106819(+) (comGH) [Streptococcus pyogenes MGAS8232]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=22541 SPYM18_RS00680 WP_002987790.1 105866..106819(+) (comGH) [Streptococcus pyogenes MGAS8232]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCCCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATTCTATTTTTGGTCA
TCCCTCTAATGCTAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comGH | Streptococcus mutans UA159 |
66.139 |
99.685 |
0.659 |
| comGH | Streptococcus mutans UA140 |
65.823 |
99.685 |
0.656 |