Detailed information NTG0224912

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: BSR25_RS06670
• Genome accession: NZ_CP020604
• Coordinates: 1334368..1336578 (-)
• Length: 736 a.a.
• NCBI ID: WP_010906130.1
• Uniprot ID: A0AAJ4MLU3
• Organism: Lactococcus lactis subsp. lactis bv. diacetylactis strain FM03
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1329368..1341578

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSR25_RS06640 (BSR25_1315)	atpA	1329412..1330914 (-)	1503	WP_004255265.1	F0F1 ATP synthase subunit alpha	-
BSR25_RS06645 (BSR25_1316)	-	1331101..1331628 (-)	528	WP_004255262.1	F0F1 ATP synthase subunit delta	-
BSR25_RS06650 (BSR25_1317)	atpF	1331630..1332136 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
BSR25_RS06655 (BSR25_1318)	atpB	1332151..1332864 (-)	714	WP_004255255.1	F0F1 ATP synthase subunit A	-
BSR25_RS06660 (BSR25_1319)	-	1332909..1333124 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
BSR25_RS06665 (BSR25_1320)	-	1333307..1334083 (-)	777	WP_004255244.1	alpha/beta hydrolase	-
BSR25_RS06670 (BSR25_1321)	comEC	1334368..1336578 (-)	2211	WP_010906130.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BSR25_RS06675 (BSR25_1322)	comEA	1336559..1337206 (-)	648	WP_010906131.1	ComEA family DNA-binding protein	Machinery gene
BSR25_RS06680 (BSR25_1323)	-	1337266..1338627 (-)	1362	WP_021214597.1	ABC transporter permease	-
BSR25_RS06685 (BSR25_1324)	-	1338624..1339556 (-)	933	WP_004255238.1	ABC transporter ATP-binding protein	-
BSR25_RS06690 (BSR25_1325)	-	1339661..1340059 (-)	399	WP_004255236.1	hypothetical protein	-
BSR25_RS06695 (BSR25_1326)	-	1340163..1340726 (-)	564	WP_004255233.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 736 a.a.
• Molecular weight: 84381.12 Da
• Isoelectric Point: 9.8268

>NTDB_id=224912 BSR25_RS06670 WP_010906130.1 1334368..1336578(-) (comEC) [Lactococcus lactis subsp. lactis bv. diacetylactis strain FM03]
MSCVLNKIPLIFLAYLSVILYFLIFNFNLICLILFIFSSLLALYRKYYLVIPFLLVMGSFFLVVKMDTIKNSGNQPTTLS
KITMIPDTIQVNGDLLSFQGKERGQNYQVYETLKSKKEQKFYQNLSQNCQLSFTGNLQIPEKQRNFNGFDNQKYLASQNI
YRQITIDKINKIVLNDTFDLHVLRRKAIVWSQTHFPKPMNDYMTGLLFGFLSKDFNQIGDIYSSLGIIHLFALSGMQVNF
FIDWFRRIILRLGITREKLNIWQIPFSIFYAFMTGFSVSVLRALFQKNIRLNPLDNLAVTTFLLMIVSPKFLLTTGGQLT
LFYAFVISMINHKISELKGIRKLLTESSVISLSVLPLLILDFHIFQPFSILLTIGFGFLFDVILLPLLLGTFLLSLIGYN
FNINHIFQILEWLIHEVDLPLHYPLVLGNPRPIELLILFFLIGLLIDNLFKKRRQIIFAGLIVCSFFICKNPVYPSITAV
DIGQGDSIFLQDKFNKKTILIDTGGRLALPQESWQKPQSQTNAEKTLIPYLESVGVSQIDQLILTHTDADHVGDFLNLAD
KIKIKEIWVSPGELTNNHFVEKLKKANIAIHISKVGDKIPIFDSALQVLSNGYTGKGDNNDSIVTYGNFYHTKFLFTGDL
EQEGEKELLKNYPKLKVDVLKVGHHGSKTSSNPDFIKEINPKLALISVGEKNRYGHPNQETLETLKKNQIRILRTDQKGA
LKLMQINQQWRIQTVR

Nucleotide

• Length: 2211 bp

>NTDB_id=224912 BSR25_RS06670 WP_010906130.1 1334368..1336578(-) (comEC) [Lactococcus lactis subsp. lactis bv. diacetylactis strain FM03]
ATGAGTTGTGTTTTGAATAAAATTCCTTTGATATTTTTAGCTTATCTTTCTGTTATCTTGTATTTTTTAATCTTCAATTT
TAATTTAATTTGTCTCATTTTGTTCATTTTTTCAAGTTTACTTGCCTTATATAGAAAATATTATTTAGTCATCCCATTTT
TATTAGTTATGGGAAGTTTTTTCTTAGTAGTAAAAATGGATACGATTAAGAATAGTGGAAATCAGCCAACCACTCTTTCC
AAAATTACAATGATCCCCGACACTATCCAAGTTAATGGTGATTTATTAAGTTTTCAAGGAAAAGAAAGAGGCCAAAATTA
TCAAGTTTACGAGACTCTAAAAAGTAAAAAAGAACAAAAATTTTATCAAAATCTAAGTCAAAATTGTCAGCTGAGTTTCA
CAGGAAACCTTCAAATTCCAGAAAAACAAAGAAATTTTAATGGATTCGATAATCAAAAGTATTTAGCGAGTCAGAATATT
TATCGGCAAATTACGATTGATAAAATTAATAAAATAGTTTTAAACGACACTTTTGACCTCCATGTTTTAAGACGAAAAGC
AATTGTCTGGTCACAAACTCATTTTCCAAAGCCAATGAATGATTATATGACTGGCTTACTTTTTGGCTTTTTAAGTAAAG
ATTTTAATCAAATAGGAGACATTTACAGTTCATTAGGAATTATTCATCTTTTTGCCTTATCGGGAATGCAAGTTAATTTT
TTCATTGATTGGTTTCGTAGAATTATTCTTCGACTAGGAATAACGAGAGAAAAATTAAATATTTGGCAAATTCCCTTTTC
AATTTTTTATGCATTTATGACAGGATTTTCGGTTTCAGTATTACGAGCTTTATTTCAAAAAAATATTCGTCTAAATCCTT
TAGATAACCTAGCAGTGACAACCTTTCTTCTGATGATTGTCAGTCCTAAATTTTTACTGACAACAGGAGGACAACTAACT
TTATTTTATGCTTTTGTCATTTCAATGATTAATCATAAAATTTCAGAACTAAAAGGAATAAGAAAATTACTGACAGAATC
ATCAGTGATTTCTTTGAGTGTTTTACCTTTACTCATTTTGGATTTTCATATCTTTCAGCCTTTTTCAATTTTACTGACGA
TTGGCTTTGGCTTTTTATTTGATGTAATCTTATTGCCTTTACTATTAGGAACTTTTCTCTTGTCTCTAATTGGCTATAAT
TTTAATATAAATCATATTTTTCAAATTCTAGAATGGCTAATTCATGAGGTTGATTTACCCTTACATTATCCTTTGGTTTT
AGGGAATCCCCGGCCAATTGAATTATTAATCTTATTTTTCCTAATCGGTTTGTTAATTGATAATCTCTTTAAGAAAAGAA
GACAAATAATTTTTGCTGGCCTAATTGTTTGTAGTTTTTTTATTTGTAAAAATCCAGTTTACCCCAGTATCACAGCAGTT
GATATTGGCCAAGGGGATAGTATTTTTTTGCAAGATAAATTTAATAAAAAAACAATTTTGATTGATACAGGCGGACGATT
AGCCCTTCCGCAAGAAAGTTGGCAAAAACCTCAAAGTCAAACAAATGCCGAAAAAACACTCATTCCATATCTTGAATCTG
TTGGAGTAAGTCAAATCGACCAGCTCATTTTGACGCATACGGACGCTGACCATGTTGGAGATTTTTTGAATTTAGCTGAT
AAAATAAAAATAAAAGAAATTTGGGTTAGCCCCGGTGAACTGACAAATAATCATTTTGTAGAAAAATTGAAGAAAGCAAA
TATTGCGATTCACATCAGTAAAGTTGGAGATAAAATTCCAATCTTTGATAGTGCTTTACAAGTTTTATCAAATGGTTATA
CAGGAAAAGGGGATAATAATGATTCTATCGTGACTTATGGAAATTTTTATCATACAAAATTTCTATTTACAGGGGATTTA
GAACAAGAAGGAGAAAAAGAACTGCTCAAGAATTATCCTAAATTGAAAGTTGATGTCTTAAAAGTAGGTCATCATGGCAG
TAAAACAAGTTCAAACCCTGACTTTATTAAAGAAATTAATCCCAAACTTGCCCTCATTTCGGTTGGAGAGAAAAATCGAT
ATGGACATCCCAATCAAGAAACTTTAGAAACATTAAAAAAAAACCAAATCAGAATACTGAGAACCGATCAAAAGGGAGCG
CTTAAACTAATGCAAATCAATCAACAGTGGCGAATCCAAACAGTTAGATAA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (28-171)

• Competence protein (Competence) (206-446)

• Metallo-beta-lactamase superfamily (Lactamase_B) (483-689)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	76.766	100	0.768
comEC/celB	Streptococcus mitis SK321	44.474	100	0.448
comEC/celB	Streptococcus mitis NCTC 12261	44.34	100	0.447
comEC/celB	Streptococcus pneumoniae TIGR4	43.607	100	0.44
comEC/celB	Streptococcus pneumoniae Rx1	43.203	100	0.436
comEC/celB	Streptococcus pneumoniae D39	43.203	100	0.436
comEC/celB	Streptococcus pneumoniae R6	43.203	100	0.436