Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   C2E56_RS09490 Genome accession   NZ_CP026084
Coordinates   1853707..1854381 (-) Length   224 a.a.
NCBI ID   WP_001238601.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain NJ1606     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1848707..1859381
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E56_RS09465 (C2E56_09830) dltC 1849323..1849562 (-) 240 WP_000351975.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  C2E56_RS09470 (C2E56_09835) dltB 1849577..1850842 (-) 1266 WP_000613595.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  C2E56_RS09475 (C2E56_09840) dltA 1850839..1852374 (-) 1536 WP_000581010.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  C2E56_RS09480 (C2E56_09845) - 1852387..1852509 (-) 123 WP_000806141.1 teichoic acid D-Ala incorporation-associated protein DltX -
  C2E56_RS09485 (C2E56_09850) dltS 1852520..1853707 (-) 1188 WP_000490527.1 two-component system sensor histidine kinase DltS -
  C2E56_RS09490 (C2E56_09855) ciaR 1853707..1854381 (-) 675 WP_001238601.1 two-component system response regulator DltR Regulator
  C2E56_RS09495 (C2E56_09860) rpmH 1854737..1854871 (-) 135 WP_000831903.1 50S ribosomal protein L34 -
  C2E56_RS09500 (C2E56_09865) - 1855055..1856410 (-) 1356 WP_000712225.1 YjiH family protein -
  C2E56_RS09505 (C2E56_09870) - 1856656..1858383 (-) 1728 WP_000429361.1 ABC transporter permease/substrate binding protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25507.50 Da        Isoelectric Point: 5.2130

>NTDB_id=224640 C2E56_RS09490 WP_001238601.1 1853707..1854381(-) (ciaR) [Streptococcus agalactiae strain NJ1606]
MRLLVVEDEKSIAEAIQALLADKGYSVDLVFDGDDGLEYILTGLYDLVLLDIMLPKRSGLSVLKRVREAGLETPIIFLTA
KSQTYDKVNGLDLGADDYITKPFEADELLARIRLRTRQSSLIRANQLRLGNIRLNTDSHELESKESSVKLSNKEFLLMEV
FMRNAKQIIPKNQLISKVWGPSDNSEYNQLEVFISFLRKKLRFLKADIEIITTKGFGYSLEEMT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=224640 C2E56_RS09490 WP_001238601.1 1853707..1854381(-) (ciaR) [Streptococcus agalactiae strain NJ1606]
ATGAGACTTCTTGTAGTTGAGGATGAAAAAAGTATAGCAGAGGCTATTCAGGCTTTATTGGCAGATAAAGGTTATTCTGT
TGATTTAGTATTTGATGGAGATGACGGGTTAGAATACATTTTGACAGGTCTCTATGATTTAGTCTTGTTGGATATTATGT
TACCCAAACGCTCAGGATTATCTGTTTTAAAAAGAGTGAGGGAAGCTGGTTTAGAAACCCCAATAATCTTTTTAACTGCA
AAATCACAGACTTATGATAAAGTTAATGGTTTAGATTTAGGGGCAGATGATTATATCACAAAACCCTTTGAAGCAGATGA
ATTGCTAGCTAGAATTAGGCTGAGAACCAGACAATCTTCTCTGATCAGAGCAAATCAATTGCGGCTTGGAAATATAAGGC
TTAACACAGATTCACATGAGCTAGAATCTAAAGAAAGTAGTGTAAAATTATCCAATAAAGAATTTCTCTTGATGGAAGTT
TTTATGCGAAATGCAAAGCAGATTATTCCTAAAAATCAGTTGATTTCTAAGGTTTGGGGACCTTCAGACAATTCAGAATA
TAACCAGTTAGAAGTATTTATTTCTTTTTTGCGAAAAAAATTGCGCTTTTTAAAAGCAGACATTGAAATAATAACCACTA
AGGGCTTTGGATATTCCTTGGAGGAGATGACATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

38.288

99.107

0.379
  ciaR Streptococcus pneumoniae Rx1

37.668

99.554

0.375
  ciaR Streptococcus pneumoniae D39

37.668

99.554

0.375
  ciaR Streptococcus pneumoniae R6

37.668

99.554

0.375
  ciaR Streptococcus pneumoniae TIGR4

37.668

99.554

0.375
  covR Lactococcus lactis subsp. lactis strain DGCC12653

36

100

0.362

Multiple sequence alignment