Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SMU_RS08745 Genome accession   NC_004350
Coordinates   1803462..1804154 (-) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans UA159     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1798462..1809154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMU_RS08720 (SMU.1919) - 1798521..1799147 (-) 627 WP_002262116.1 hypothetical protein -
  SMU_RS08725 (SMU.1920) der 1799222..1800532 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  SMU_RS08730 (SMU.1921) dnaI 1800545..1801444 (-) 900 WP_002262118.1 primosomal protein DnaI -
  SMU_RS08735 (SMU.1922) - 1801445..1802614 (-) 1170 WP_002262119.1 DnaD domain protein -
  SMU_RS08740 (SMU.1923c) nrdR 1802601..1803092 (-) 492 WP_002262120.1 transcriptional regulator NrdR -
  SMU_RS08745 (SMU.1924) covR 1803462..1804154 (-) 693 WP_002262121.1 response regulator GcrR Regulator
  SMU_RS08750 (SMU.1925c) - 1804511..1805047 (-) 537 WP_002262122.1 DUF177 domain-containing protein -
  SMU_RS08755 (SMU.1926) - 1805040..1805615 (-) 576 WP_002262123.1 TetR/AcrR family transcriptional regulator -
  SMU_RS08760 (SMU.1927) - 1805723..1806430 (+) 708 WP_002262124.1 ABC transporter ATP-binding protein -
  SMU_RS08765 (SMU.1928) - 1806432..1809044 (+) 2613 WP_002263841.1 ABC transporter permease -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=22432 SMU_RS08745 WP_002262121.1 1803462..1804154(-) (covR) [Streptococcus mutans UA159]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=22432 SMU_RS08745 WP_002262121.1 1803462..1804154(-) (covR) [Streptococcus mutans UA159]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCTATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAGCATTCTTCTAAAAATGACACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422

Multiple sequence alignment