Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6J88_RS19945 Genome accession   NZ_CP020452
Coordinates   1151598..1151897 (+) Length   99 a.a.
NCBI ID   WP_080613763.1    Uniprot ID   -
Organism   Neisseria mucosa strain FDAARGOS_260     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 1152145..1157488 1151598..1151897 flank 248


Gene organization within MGE regions


Location: 1151598..1157488
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J88_RS19945 (A6J88_05860) comE 1151598..1151897 (+) 300 WP_080613763.1 ComEA family DNA-binding protein Machinery gene
  A6J88_RS19950 (A6J88_05865) - 1152145..1153152 (+) 1008 WP_080613764.1 IS5 family transposase -
  A6J88_RS19960 (A6J88_05870) nrdR 1153503..1153964 (+) 462 WP_003776195.1 transcriptional regulator NrdR -
  A6J88_RS19965 (A6J88_05875) - 1154005..1154535 (+) 531 WP_240594062.1 hypothetical protein -
  A6J88_RS19970 (A6J88_05880) ribD 1154600..1155697 (+) 1098 WP_070442055.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
  A6J88_RS19975 (A6J88_05885) - 1155762..1156508 (-) 747 Protein_1085 IS5 family transposase -
  A6J88_RS19985 (A6J88_14035) - 1157348..1157488 (-) 141 Protein_1087 IS5/IS1182 family transposase -

Sequence

Protein


Download         Length: 99 a.a.        Molecular weight: 10254.01 Da        Isoelectric Point: 10.6262

>NTDB_id=223304 A6J88_RS19945 WP_080613763.1 1151598..1151897(+) (comE) [Neisseria mucosa strain FDAARGOS_260]
MKKFLFAALSVLTASLSLAAVNINTASPSELEALPGIGPAKAKAIVDYRQQHGAFKSVEELKNVKGIGEGIFSKLKAEAT
VAPAPANPKAKNAVPSPKK

Nucleotide


Download         Length: 300 bp        

>NTDB_id=223304 A6J88_RS19945 WP_080613763.1 1151598..1151897(+) (comE) [Neisseria mucosa strain FDAARGOS_260]
ATGAAAAAATTCCTCTTTGCCGCACTCTCCGTTCTGACCGCCTCGCTGTCGCTGGCCGCTGTCAACATCAATACCGCTTC
CCCGTCCGAATTGGAAGCCCTGCCCGGCATCGGTCCGGCCAAAGCCAAAGCCATTGTGGACTACCGCCAGCAGCACGGTG
CCTTCAAATCGGTGGAAGAGCTCAAAAACGTTAAAGGCATCGGCGAGGGTATCTTCTCCAAACTGAAGGCCGAAGCAACC
GTCGCGCCCGCACCTGCCAACCCAAAAGCTAAAAACGCCGTCCCATCACCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(20-77)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

59

100

0.596
  comE Neisseria gonorrhoeae MS11

59

100

0.596
  comE Neisseria gonorrhoeae MS11

59

100

0.596
  comE Neisseria gonorrhoeae MS11

59

100

0.596
  Cj0011c Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

53.086

81.818

0.434
  comEA Vibrio parahaemolyticus RIMD 2210633

46.512

86.869

0.404

Multiple sequence alignment