Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   A6J87_RS09675 Genome accession   NZ_CP020451
Coordinates   2012247..2013662 (+) Length   471 a.a.
NCBI ID   WP_080611984.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_259     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2007247..2018662
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J87_RS09650 (A6J87_09590) - 2007697..2008269 (-) 573 WP_021144028.1 ECF transporter S component -
  A6J87_RS09655 (A6J87_09595) coaC 2008298..2008843 (-) 546 WP_070577368.1 phosphopantothenoylcysteine decarboxylase -
  A6J87_RS09660 (A6J87_09600) - 2008836..2009519 (-) 684 WP_013990463.1 phosphopantothenate--cysteine ligase -
  A6J87_RS09665 (A6J87_09605) - 2009714..2011384 (+) 1671 WP_013990464.1 formate--tetrahydrofolate ligase -
  A6J87_RS09670 (A6J87_09610) ciaR 2011583..2012257 (+) 675 WP_049546057.1 response regulator transcription factor Regulator
  A6J87_RS09675 (A6J87_09615) ciaH 2012247..2013662 (+) 1416 WP_080611984.1 cell wall metabolism sensor histidine kinase WalK Regulator
  A6J87_RS09680 (A6J87_09620) rpsT 2013747..2013983 (-) 237 WP_037597891.1 30S ribosomal protein S20 -
  A6J87_RS09685 (A6J87_09625) coaA 2014053..2014973 (-) 921 WP_037597889.1 type I pantothenate kinase -
  A6J87_RS09690 (A6J87_09630) - 2015087..2015677 (+) 591 WP_073951006.1 class I SAM-dependent methyltransferase -
  A6J87_RS09695 (A6J87_09635) - 2015674..2016951 (+) 1278 WP_080611985.1 pyrimidine-nucleoside phosphorylase -
  A6J87_RS09700 (A6J87_09640) deoC 2016985..2017647 (+) 663 WP_002891127.1 deoxyribose-phosphate aldolase -
  A6J87_RS09705 (A6J87_09645) - 2017634..2018032 (+) 399 WP_073951002.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53479.21 Da        Isoelectric Point: 8.7681

>NTDB_id=223280 A6J87_RS09675 WP_080611984.1 2012247..2013662(+) (ciaH) [Streptococcus salivarius strain FDAARGOS_259]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGSTDETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTGQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNHPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=223280 A6J87_RS09675 WP_080611984.1 2012247..2013662(+) (ciaH) [Streptococcus salivarius strain FDAARGOS_259]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGGTTTAAGTCGTTCATTCATTTCTTTGCTAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCAAATGTGGATTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATCTACCAAGCCTATGATACTAAAGGATCGACAGATGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCTCACGATTTATCTGTTGCGGCGAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGACAAATTTTCTAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAGAAAGT
AGACAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCTACTGAACGTT
ATGTTAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAAGTTCTTTTCCGCAAGCCTGAGAGTACTATTTTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACTACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGGTCAAAACCAAGTTAGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATTTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTGGGCTTATCACTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TCAAGGACAATCATCCGAAGGGGACTATTTTTGAAGTTAAAATTACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.522

97.665

0.552
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment