Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   A6J85_RS00740 Genome accession   NZ_CP020450
Coordinates   130824..132125 (-) Length   433 a.a.
NCBI ID   WP_082307130.1    Uniprot ID   -
Organism   Streptococcus gordonii strain FDAARGOS_257     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 125824..137125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J85_RS00730 (A6J85_00725) hpf 129535..130077 (-) 543 WP_012000104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  A6J85_RS00735 (A6J85_00730) comFC/cflB 130162..130827 (-) 666 WP_061596056.1 ComF family protein Machinery gene
  A6J85_RS00740 (A6J85_00735) comFA/cflA 130824..132125 (-) 1302 WP_082307130.1 DEAD/DEAH box helicase Machinery gene
  A6J85_RS00745 (A6J85_00740) - 132181..132813 (+) 633 WP_045772978.1 YigZ family protein -
  A6J85_RS00750 (A6J85_00745) cysK 132911..133840 (+) 930 WP_061599612.1 cysteine synthase A -
  A6J85_RS00755 (A6J85_00750) - 133874..134260 (-) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -
  A6J85_RS00760 (A6J85_00755) - 134257..135660 (-) 1404 WP_082307131.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  A6J85_RS00765 (A6J85_00760) - 135748..136380 (-) 633 WP_082307132.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49482.41 Da        Isoelectric Point: 8.3704

>NTDB_id=223148 A6J85_RS00740 WP_082307130.1 130824..132125(-) (comFA/cflA) [Streptococcus gordonii strain FDAARGOS_257]
MLELQDCLGRIFTKEQLPPELLKKAKRLSSIFEKKGELFCSRCYSQIDKERYLLPIGAYYCRECILLGRVRSDEDLYFFP
QESFPFISSLKWLGQLTEYQERVSKGLLEGVQNKQDTLVHAVTGAGKTEMIYQVVAQVLDQGGAVCIASPRIDVCLELYR
RLKEDFSCDISLLHGESDPYSRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPVLYHAVEQAVKNEGTTIFLTATS
TDELDKKVQKGILKRLSLPRRFHGNPLIIPQKVWLSGLNKDLQREKLPAKLVKYLRKQRKTKFPLLIFASEIKKGQEIKQ
VLQKYFPEENVGFVASTTENRLEIVQDFRDNKISILVTTTILERGVTFPCVDVIVLEANHRLFTRSALVQIGGRVGRSME
RPTGDLLFFHDGTNIQIEKAINEIKAMNREAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=223148 A6J85_RS00740 WP_082307130.1 130824..132125(-) (comFA/cflA) [Streptococcus gordonii strain FDAARGOS_257]
ATGTTAGAATTGCAAGATTGTTTAGGGCGAATTTTTACTAAAGAACAGTTACCTCCTGAACTACTTAAGAAAGCTAAAAG
ACTATCATCAATTTTTGAAAAAAAGGGAGAACTCTTTTGTTCTCGCTGCTACAGTCAGATTGATAAGGAAAGATATTTAT
TGCCAATTGGTGCATATTATTGTAGAGAATGCATTCTTCTAGGGAGAGTGCGTAGTGACGAAGATCTTTATTTTTTTCCA
CAAGAGTCTTTTCCTTTTATATCGAGTTTGAAATGGCTTGGCCAATTGACAGAATATCAGGAAAGAGTTTCTAAAGGGTT
ACTTGAAGGAGTACAAAATAAGCAGGATACTTTAGTCCACGCTGTAACTGGAGCAGGAAAAACAGAGATGATATATCAAG
TGGTTGCTCAGGTGTTAGATCAAGGAGGTGCTGTCTGTATAGCTAGTCCTCGGATAGATGTCTGTTTGGAACTTTACCGG
CGTTTAAAAGAAGATTTTTCATGTGATATTTCCCTATTGCATGGGGAGTCCGACCCCTATTCACGCAGTCCCTTAGTGAT
TGCAACAACTCATCAATTACTAAAATTTTATCAGGCATTTGATTTACTCATTGTTGATGAGGTAGATGCCTTTCCTTATG
TAGATAACCCTGTGCTCTATCATGCTGTCGAGCAAGCAGTAAAAAATGAAGGAACTACAATATTCCTAACGGCTACGTCA
ACTGATGAGCTTGATAAAAAAGTCCAAAAAGGAATTTTGAAAAGATTAAGTTTGCCAAGACGCTTTCATGGAAATCCCTT
GATTATCCCACAAAAAGTATGGCTTTCTGGTCTAAATAAAGACCTCCAAAGAGAAAAACTACCAGCCAAGTTAGTCAAGT
ATCTGAGAAAACAAAGAAAAACAAAATTTCCACTCTTAATTTTTGCTTCAGAAATTAAAAAAGGGCAGGAGATAAAGCAA
GTCTTACAAAAATATTTTCCAGAAGAAAATGTAGGTTTTGTAGCCTCTACAACGGAAAATAGATTAGAAATAGTGCAAGA
TTTTCGAGATAACAAAATAAGTATACTAGTTACAACTACAATTTTAGAAAGAGGGGTTACTTTTCCCTGTGTAGATGTAA
TTGTTTTAGAAGCTAACCATCGTCTCTTTACAAGGAGTGCTTTAGTACAAATTGGCGGGCGAGTGGGAAGAAGTATGGAA
CGACCGACAGGTGACTTACTATTTTTCCATGATGGCACTAATATACAGATAGAAAAAGCAATCAATGAAATTAAAGCAAT
GAACAGAGAGGCTGGCTTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(97-245)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

69.159

98.845

0.684
  comFA/cflA Streptococcus pneumoniae D39

69.159

98.845

0.684
  comFA/cflA Streptococcus pneumoniae R6

69.159

98.845

0.684
  comFA/cflA Streptococcus pneumoniae TIGR4

69.159

98.845

0.684
  comFA/cflA Streptococcus mitis NCTC 12261

69.014

98.383

0.679
  comFA/cflA Streptococcus mitis SK321

69.014

98.383

0.679
  comFA Lactococcus lactis subsp. cremoris KW2

54.061

90.993

0.492
  comFA Latilactobacillus sakei subsp. sakei 23K

39.907

99.538

0.397
  comFA Bacillus subtilis subsp. subtilis str. 168

39.32

95.15

0.374

Multiple sequence alignment