Detailed information NTG0223024

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: A6J72_RS07600
• Genome accession: NZ_CP020433
• Coordinates: 1514321..1515388 (+)
• Length: 355 a.a.
• NCBI ID: WP_009569325.1
• Uniprot ID: A0A1L7MWH2
• Organism: Streptococcus intermedius strain FDAARGOS_233
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1509321..1520388

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J72_RS07585 (A6J72_07580)	amiA3	1509537..1511516 (+)	1980	WP_082312135.1	peptide ABC transporter substrate-binding protein	Regulator
A6J72_RS07590 (A6J72_07585)	amiC	1511890..1513386 (+)	1497	WP_082312136.1	ABC transporter permease	Regulator
A6J72_RS07595 (A6J72_07590)	amiD	1513386..1514312 (+)	927	WP_003074404.1	oligopeptide ABC transporter permease OppC	Regulator
A6J72_RS07600 (A6J72_07595)	amiE	1514321..1515388 (+)	1068	WP_009569325.1	ABC transporter ATP-binding protein	Regulator
A6J72_RS07605 (A6J72_07600)	amiF	1515399..1516322 (+)	924	WP_003074407.1	ATP-binding cassette domain-containing protein	Regulator
A6J72_RS07610 (A6J72_07605)	-	1516449..1517267 (+)	819	WP_082312137.1	Cof-type HAD-IIB family hydrolase	-
A6J72_RS07615 (A6J72_07610)	-	1517353..1518318 (-)	966	WP_003074411.1	LacI family DNA-binding transcriptional regulator	-
A6J72_RS07620 (A6J72_07615)	-	1518299..1519753 (-)	1455	WP_082312138.1	sucrose-6-phosphate hydrolase	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39608.28 Da
• Isoelectric Point: 4.8594

>NTDB_id=223024 A6J72_RS07600 WP_009569325.1 1514321..1515388(+) (amiE) [Streptococcus intermedius strain FDAARGOS_233]
MTQEKNVILTARDIVVEFDVRDKVLTAIRGVSLDLIEGEVLALVGESGSGKSVLTKTFTGMLEDNGRVAQGSINYRGQDL
TKLKSNKDWEPIRGVKIATIFQDPMTSLDPINTIGSQITEVIVKHQKKTAKEAKEMAVDYMNKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIIDLLKSLQQEYQFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGELYSIPGTPPSLYSHLQGDAFALRSDYAMEIDFEEKPPQIYVSDTHWAK
TWLLHENAPKVNKPAVIDDLHEKISSKMGFAHLNA

Nucleotide

• Length: 1068 bp

>NTDB_id=223024 A6J72_RS07600 WP_009569325.1 1514321..1515388(+) (amiE) [Streptococcus intermedius strain FDAARGOS_233]
ATGACACAAGAAAAAAATGTAATATTGACTGCTCGCGATATTGTCGTGGAATTTGATGTTCGTGACAAAGTTTTAACAGC
TATTCGGGGCGTTTCGCTTGACCTCATCGAAGGTGAAGTTCTTGCGCTTGTAGGAGAATCTGGTTCTGGTAAGTCCGTTT
TGACAAAAACCTTTACTGGAATGTTAGAGGATAATGGTCGAGTAGCGCAAGGATCGATTAACTATCGTGGACAAGATTTG
ACAAAATTGAAATCCAATAAAGATTGGGAACCTATTCGTGGTGTTAAAATTGCGACAATTTTCCAAGATCCAATGACAAG
TTTAGACCCAATTAATACGATTGGTAGCCAGATTACAGAAGTTATTGTAAAACATCAAAAGAAAACGGCAAAAGAAGCGA
AGGAAATGGCTGTTGACTATATGAATAAAGTAGGTATTCCTGATGCTGAAAAGCGTTTTAATGAGTATCCTTTCCAATAT
TCAGGGGGAATGCGCCAACGGATTGTTATTGCCATTGCACTTGCTTGTCGTCCGGATATTCTAATCTGTGATGAACCTAC
GACAGCACTGGATGTTACCATTCAAGCGCAAATCATTGATTTGTTGAAATCATTGCAACAAGAGTATCAGTTCACCACTA
TTTTTATAACCCACGACCTTGGAGTAGTAGCAAGTATTGCGGATAAGGTTGCTGTTATGTATGCTGGAGAAATCGTCGAG
TATGGTACAGTAGAAGAGGTCTTTTATGATCCACGTCATCCGTATACTTGGAGTTTGTTATCAAGCTTACCACAGTTGGC
AGACGATAAAGGAGAGCTGTACTCTATTCCTGGTACACCACCGTCTCTTTATTCACATTTGCAAGGAGATGCGTTTGCTC
TCCGCTCAGACTATGCGATGGAAATTGATTTTGAGGAAAAACCGCCTCAAATCTATGTATCAGATACGCATTGGGCAAAA
ACATGGTTACTTCATGAAAATGCTCCAAAAGTGAATAAACCTGCTGTTATTGATGATTTACACGAAAAAATTAGCTCAAA
AATGGGATTTGCCCATTTAAATGCTTAG

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

3D structure

• AlphaFold DB: A0A1L7MWH2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	86.441	99.718	0.862
amiE	Streptococcus thermophilus LMG 18311	85.028	99.718	0.848
amiE	Streptococcus thermophilus LMD-9	85.028	99.718	0.848
oppD	Streptococcus mutans UA159	56.25	99.155	0.558