Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   A6J31_RS10295 Genome accession   NZ_CP020431
Coordinates   1991924..1992673 (+) Length   249 a.a.
NCBI ID   WP_014633817.1    Uniprot ID   A0AB35IU89
Organism   Streptococcus sp. FDAARGOS_192     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1986924..1997673
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS10275 (A6J31_10215) - 1987939..1988679 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  A6J31_RS10280 (A6J31_10220) - 1988679..1990226 (-) 1548 WP_080611127.1 ABC transporter substrate-binding protein/permease -
  A6J31_RS10285 (A6J31_10225) - 1990432..1991286 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  A6J31_RS10290 (A6J31_10230) - 1991346..1991717 (-) 372 WP_080611128.1 DUF3021 family protein -
  A6J31_RS10295 (A6J31_10235) mecA 1991924..1992673 (+) 750 WP_014633817.1 adaptor protein MecA Regulator
  A6J31_RS10300 (A6J31_10240) - 1992677..1993834 (+) 1158 WP_080611130.1 glycosyltransferase family 4 protein -
  A6J31_RS10305 (A6J31_10245) sufC 1993997..1994767 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  A6J31_RS10310 (A6J31_10250) sufD 1994804..1996066 (+) 1263 WP_013989976.1 Fe-S cluster assembly protein SufD -
  A6J31_RS10315 (A6J31_10255) - 1996120..1997352 (+) 1233 WP_002886438.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29100.68 Da        Isoelectric Point: 4.0182

>NTDB_id=222908 A6J31_RS10295 WP_014633817.1 1991924..1992673(+) (mecA) [Streptococcus sp. FDAARGOS_192]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDIPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEEDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=222908 A6J31_RS10295 WP_014633817.1 1991924..1992673(+) (mecA) [Streptococcus sp. FDAARGOS_192]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAAGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGATGACTATTCAGGGCTTTCTCCAGAAGAGTTCCTCAAGGCCCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGACTTTGATCAAGTGGTGACTTTTACGCAAGGTTTGAAGGATATACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTACATGACGATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGAGGACGCCTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment