Detailed information NTG0222907

Bioinformatically predicted

Overview

• Name: comX
• Type: Regulator
• Locus tag: A6J31_RS10165
• Genome accession: NZ_CP020431
• Coordinates: 1961273..1961770 (+)
• Length: 165 a.a.
• NCBI ID: WP_002885610.1
• Uniprot ID: A0A2I1TJX9
• Organism: Streptococcus sp. FDAARGOS_192
• Function: activate transcription of late competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1956273..1966770

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J31_RS10165 (A6J31_10105)	comX	1961273..1961770 (+)	498	WP_002885610.1	sigma factor	Regulator
A6J31_RS10170 (A6J31_10110)	-	1961878..1962720 (-)	843	WP_080611109.1	mechanosensitive ion channel family protein	-
A6J31_RS10175 (A6J31_10115)	tig	1962863..1964146 (+)	1284	WP_002889721.1	trigger factor	-
A6J31_RS10180 (A6J31_10120)	rpoE	1964304..1964879 (+)	576	WP_002885605.1	DNA-directed RNA polymerase subunit delta	-
A6J31_RS10185 (A6J31_10125)	-	1965132..1966736 (+)	1605	WP_080611110.1	CTP synthase	-

Sequence

Protein

• Length: 165 a.a.
• Molecular weight: 20008.84 Da
• Isoelectric Point: 4.9953

>NTDB_id=222907 A6J31_RS10165 WP_002885610.1 1961273..1961770(+) (comX) [Streptococcus sp. FDAARGOS_192]
MEQEVFVHAYEVVRPIVLKASRQYFIQLWDLADMEQEAMMTLYQLLEKFPELKSDDDKLRRYFKTKFRNRLNDEVRRQES
VKRQANRQCYIEISDIAFCLPNKELDAVDRLVYDEQLNAFRNQLSSEDATKLDRLLAGECFRGRKKMIRELKFWMVDFDP
YNEDD

Nucleotide

• Length: 498 bp

>NTDB_id=222907 A6J31_RS10165 WP_002885610.1 1961273..1961770(+) (comX) [Streptococcus sp. FDAARGOS_192]
ATGGAACAAGAAGTTTTTGTTCATGCATATGAAGTTGTAAGGCCGATTGTACTTAAGGCTAGTAGACAATATTTCATCCA
ACTTTGGGACCTTGCTGATATGGAGCAAGAGGCTATGATGACGCTTTATCAGCTTTTAGAAAAGTTTCCTGAATTAAAGT
CTGATGATGATAAGTTACGGCGTTATTTTAAAACGAAATTTAGGAATAGGCTTAATGATGAGGTTAGAAGGCAGGAGTCT
GTAAAACGACAAGCTAATCGACAATGTTATATTGAAATTTCAGATATTGCTTTTTGTCTTCCGAATAAAGAGTTAGATGC
TGTTGATAGGCTTGTTTATGATGAGCAGCTTAATGCTTTTCGTAATCAGTTGTCTTCGGAAGATGCTACTAAGTTGGACC
GTTTGCTAGCTGGGGAGTGTTTTAGAGGTCGAAAAAAGATGATTCGAGAGTTAAAATTTTGGATGGTTGATTTTGATCCT
TACAATGAAGATGATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A0A2I1TJX9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comX	Streptococcus salivarius SK126	100	100	1
comX/sigX	Streptococcus salivarius strain HSISS4	99.394	100	0.994
comX	Streptococcus thermophilus LMD-9	88.485	100	0.885
comX	Streptococcus thermophilus LMG 18311	88.485	100	0.885
comR/comR2	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comR/comR1	Streptococcus gordonii str. Challis substr. CH1	43.226	93.939	0.406
comX	Streptococcus sobrinus strain NIDR 6715-7	40.606	100	0.406
comX/sigX	Streptococcus mutans UA159	41.667	94.545	0.394
comX/sigX	Streptococcus infantarius subsp. infantarius ATCC BAA-102	41.026	94.545	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes JRS4	42.667	90.909	0.388
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS8232	42.667	90.909	0.388
comX/sigX/comX1/sigX1	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX/comX2/sigX2	Streptococcus pyogenes MGAS315	42	90.909	0.382
comX/sigX	Streptococcus suis D9	39.869	92.727	0.37
comX/sigX	Streptococcus suis isolate S10	39.869	92.727	0.37
comX/sigX	Streptococcus suis P1/7	39.869	92.727	0.37