Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   A6J31_RS05005 Genome accession   NZ_CP020431
Coordinates   828798..830213 (-) Length   471 a.a.
NCBI ID   WP_080610582.1    Uniprot ID   -
Organism   Streptococcus sp. FDAARGOS_192     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 823798..835213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6J31_RS04975 (A6J31_04930) - 824436..824834 (-) 399 WP_037600754.1 cytidine deaminase -
  A6J31_RS04980 (A6J31_04935) deoC 824821..825483 (-) 663 WP_013990470.1 deoxyribose-phosphate aldolase -
  A6J31_RS04985 (A6J31_04940) - 825517..826794 (-) 1278 WP_080610581.1 pyrimidine-nucleoside phosphorylase -
  A6J31_RS04990 (A6J31_04945) - 826791..827381 (-) 591 WP_013990468.1 class I SAM-dependent methyltransferase -
  A6J31_RS04995 (A6J31_04950) coaA 827494..828414 (+) 921 WP_013990467.1 type I pantothenate kinase -
  A6J31_RS05000 (A6J31_04955) rpsT 828484..828720 (+) 237 WP_004182129.1 30S ribosomal protein S20 -
  A6J31_RS05005 (A6J31_04960) ciaH 828798..830213 (-) 1416 WP_080610582.1 sensor histidine kinase Regulator
  A6J31_RS05010 (A6J31_04965) ciaR 830203..830877 (-) 675 WP_002891134.1 response regulator transcription factor Regulator
  A6J31_RS05015 (A6J31_04970) - 831076..832746 (-) 1671 WP_013990464.1 formate--tetrahydrofolate ligase -
  A6J31_RS05020 (A6J31_04975) - 832941..833624 (+) 684 WP_013990463.1 phosphopantothenate--cysteine ligase -
  A6J31_RS05025 (A6J31_04980) coaC 833617..834162 (+) 546 WP_013990462.1 phosphopantothenoylcysteine decarboxylase -
  A6J31_RS05030 (A6J31_04985) - 834191..834763 (+) 573 WP_022496698.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53474.26 Da        Isoelectric Point: 8.7661

>NTDB_id=222871 A6J31_RS05005 WP_080610582.1 828798..830213(-) (ciaH) [Streptococcus sp. FDAARGOS_192]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVGRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=222871 A6J31_RS05005 WP_080610582.1 828798..830213(-) (ciaH) [Streptococcus sp. FDAARGOS_192]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCCTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTACAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTGGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATGCCCCTCACGATTTATCTGTTGCGGCAAACACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTATCGTCTGATCACTGAGAAAGT
AGACAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCAACTGAACGTT
ATGTCAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTCTTGTCAGTTGCAGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAAGCATTTGTTGAAAATGCTAGTCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGGTTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCATCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACTAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTGGTCGTCCAATCCAGACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGACGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGGATATCAGATAGTGATAAGAAAAAAATCTTTGATCGATTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAGATTACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment