Detailed information NTG0222726

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: C2H95_RS18045
• Genome accession: NZ_CP026037
• Coordinates: 3494807..3495811 (-)
• Length: 334 a.a.
• NCBI ID: WP_003229285.1
• Uniprot ID: P25144
• Organism: Bacillus subtilis strain PK5_17
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 3489807..3500811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2H95_RS18020 (C2H95_17945)	acuA	3490735..3491367 (+)	633	WP_014480567.1	acetoin utilization protein acetyltransferase AcuA	-
C2H95_RS18025 (C2H95_17950)	acuB	3491394..3492038 (+)	645	WP_003229294.1	acetoin utilization AcuB family protein	-
C2H95_RS18030 (C2H95_17955)	acuC	3492035..3493198 (+)	1164	WP_015714526.1	acetoin utilization protein AcuC	-
C2H95_RS18035 (C2H95_17960)	motS	3493211..3493936 (-)	726	WP_249849515.1	flagellar motor protein MotS	-
C2H95_RS18040 (C2H95_17965)	motP	3493926..3494744 (-)	819	WP_014477672.1	flagellar motor protein MotP	-
C2H95_RS18045 (C2H95_17970)	ccpA	3494807..3495811 (-)	1005	WP_003229285.1	catabolite control protein A	Regulator
C2H95_RS18050 (C2H95_17975)	aroX	3496087..3497163 (-)	1077	WP_003223454.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
C2H95_RS18055 (C2H95_17980)	ytxJ	3497403..3497729 (-)	327	WP_249849516.1	bacillithiol system redox-active protein YtxJ	-
C2H95_RS18060 (C2H95_17985)	ytxH	3497753..3498184 (-)	432	WP_072175304.1	YtxH domain-containing protein	-
C2H95_RS18065 (C2H95_17990)	ytxG	3498215..3498637 (-)	423	WP_003229276.1	DUF948 domain-containing protein	-
C2H95_RS18070 (C2H95_17995)	murC	3498799..3500097 (-)	1299	WP_015714530.1	UDP-N-acetylmuramate--L-alanine ligase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 36940.34 Da
• Isoelectric Point: 5.0249

>NTDB_id=222726 C2H95_RS18045 WP_003229285.1 3494807..3495811(-) (ccpA) [Bacillus subtilis strain PK5_17]
MSNITIYDVAREANVSMATVSRVVNGNPNVKPTTRKKVLEAIERLGYRPNAVARGLASKKTTTVGVIIPDISSIFYSELA
RGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGKQVDGIVFMGGNITDEHVAEFKRSPVPIVLAASVEEQEETPSVAI
DYEQAIYDAVKLLVDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAEGDYTYDSGLEALQHLMSLDKK
PTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSLMVRPQLSTVVQPTYDIGAVAMRLLTKLMNKEPVEEHIV
ELPHRIELRKSTKS

Nucleotide

• Length: 1005 bp

>NTDB_id=222726 C2H95_RS18045 WP_003229285.1 3494807..3495811(-) (ccpA) [Bacillus subtilis strain PK5_17]
ATGAGCAATATTACGATCTACGATGTAGCGAGAGAAGCTAATGTAAGCATGGCAACCGTTTCCCGTGTCGTGAACGGCAA
CCCGAATGTAAAACCGACAACGAGGAAAAAAGTCTTGGAAGCCATTGAACGTCTCGGTTACCGTCCAAACGCGGTGGCAA
GAGGGCTGGCAAGTAAAAAAACAACAACTGTAGGTGTCATCATTCCCGATATCTCAAGCATTTTCTATTCAGAGCTTGCA
CGCGGAATTGAAGATATCGCGACAATGTATAAATACAATATTATTTTGAGCAACTCTGACCAAAACATGGAGAAAGAGCT
CCATTTGTTAAACACAATGCTCGGCAAACAAGTGGACGGCATCGTGTTTATGGGCGGAAACATTACGGACGAGCATGTGG
CGGAATTTAAGCGTTCCCCAGTGCCGATCGTACTTGCCGCTTCTGTAGAAGAGCAGGAGGAAACACCGTCAGTCGCTATC
GATTACGAACAGGCGATTTATGATGCTGTGAAGCTTTTGGTTGATAAAGGACATACAGACATCGCATTCGTTTCCGGACC
AATGGCAGAACCGATCAACCGTTCAAAAAAACTCCAAGGCTACAAACGTGCGCTTGAAGAAGCGAACCTTCCGTTTAATG
AACAATTTGTAGCTGAAGGGGATTACACATATGATTCCGGACTCGAAGCACTGCAGCATCTGATGAGCCTGGATAAAAAA
CCGACAGCCATTCTTTCTGCAACTGATGAAATGGCACTCGGCATTATCCATGCCGCTCAGGATCAGGGCTTATCCATTCC
GGAGGATCTCGACATTATCGGTTTTGATAATACAAGATTAAGCCTCATGGTTCGTCCGCAGCTTTCAACAGTTGTTCAGC
CGACATATGATATCGGCGCCGTTGCGATGAGACTGCTGACGAAGCTCATGAATAAAGAGCCGGTTGAAGAGCATATCGTC
GAACTGCCGCACCGTATAGAGCTTAGAAAGTCAACCAAGTCATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (5-50)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-332)

3D structure

• PDB: 1ZVV
• PDB: 2FEP
• PDB: 3OQM
• PDB: 3OQN
• PDB: 3OQO

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	54.545	98.802	0.539
ccpA	Streptococcus gordonii str. Challis substr. CH1	53.636	98.802	0.53
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	50.602	99.401	0.503