Detailed information NTG0222569

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: A6J46_RS04135
• Genome accession: NZ_CP020419
• Coordinates: 685367..685816 (+)
• Length: 149 a.a.
• NCBI ID: WP_002214937.1
• Uniprot ID: A0AA44U8B7
• Organism: Neisseria gonorrhoeae strain FDAARGOS_207
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	678386..692811	685367..685816	within	0

Gene organization within MGE regions

Location: 678386..692811

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6J46_RS04085 (A6J46_13135)	-	678386..679039 (+)	654	Protein_699	TIGR01621 family pseudouridine synthase	-
A6J46_RS13900 (A6J46_04095)	-	684663..684779 (+)	117	Protein_700	competence protein ComE	-
A6J46_RS04130 (A6J46_04100)	comE	684884..685279 (+)	396	WP_003703428.1	helix-hairpin-helix domain-containing protein	Machinery gene
A6J46_RS04135 (A6J46_04105)	comP	685367..685816 (+)	450	WP_002214937.1	type IV pilin protein	Machinery gene
A6J46_RS04150 (A6J46_04120)	-	686726..687316 (+)	591	WP_080229150.1	DNA cytosine methyltransferase	-
A6J46_RS04155 (A6J46_04125)	-	687355..687684 (+)	330	WP_002234365.1	DNA cytosine methyltransferase	-
A6J46_RS13905	-	687698..688555 (+)	858	WP_012503917.1	ATP-binding protein	-
A6J46_RS13910	-	688745..689341 (+)	597	WP_012503916.1	TIGR02391 family protein	-
A6J46_RS04165 (A6J46_04140)	-	689347..689769 (+)	423	WP_003691751.1	very short patch repair endonuclease	-
A6J46_RS04175 (A6J46_04145)	-	689907..691252 (+)	1346	Protein_708	replication initiation factor domain-containing protein	-
A6J46_RS04180 (A6J46_04150)	-	691297..691587 (+)	291	WP_002216601.1	hypothetical protein	-
A6J46_RS04185 (A6J46_04155)	-	691592..691789 (+)	198	WP_003689600.1	hypothetical protein	-
A6J46_RS04190 (A6J46_13160)	-	691863..692081 (+)	219	WP_003691584.1	major capsid protein	-
A6J46_RS04195 (A6J46_04160)	-	692088..692366 (+)	279	WP_003689168.1	hypothetical protein	-
A6J46_RS04200 (A6J46_04165)	-	692494..692811 (+)	318	WP_003696077.1	DUF1132 family protein	-

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16834.81 Da
• Isoelectric Point: 9.7951

>NTDB_id=222569 A6J46_RS04135 WP_002214937.1 685367..685816(+) (comP) [Neisseria gonorrhoeae strain FDAARGOS_207]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=222569 A6J46_RS04135 WP_002214937.1 685367..685816(+) (comP) [Neisseria gonorrhoeae strain FDAARGOS_207]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	100	100	1
comP	Neisseria meningitidis 8013	99.329	100	0.993
comP	Neisseria subflava NJ9703	49.66	98.658	0.49