Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   C2H93_RS18400 Genome accession   NZ_CP026036
Coordinates   3616343..3617545 (-) Length   400 a.a.
NCBI ID   WP_021481077.1    Uniprot ID   -
Organism   Bacillus subtilis strain PK5_16     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3611343..3622545
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2H93_RS18375 (C2H93_18385) rocE 3611587..3612990 (-) 1404 WP_021481073.1 amino acid permease -
  C2H93_RS18380 (C2H93_18390) rocD 3613213..3614418 (-) 1206 WP_249852430.1 ornithine aminotransferase -
  C2H93_RS18385 (C2H93_18395) rocR 3614659..3616044 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  C2H93_RS18390 (C2H93_18400) - 3616026..3616172 (-) 147 Protein_3620 ATP-binding protein -
  C2H93_RS18395 - 3616197..3616323 (-) 127 Protein_3621 hypothetical protein -
  C2H93_RS18400 (C2H93_18405) htrA 3616343..3617545 (-) 1203 WP_021481077.1 serine protease HtrC Regulator
  C2H93_RS18405 (C2H93_18410) vicX 3617627..3618421 (-) 795 WP_021481078.1 MBL fold metallo-hydrolase Regulator
  C2H93_RS18410 (C2H93_18415) walI 3618443..3619285 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  C2H93_RS18415 (C2H93_18420) walH 3619272..3620639 (-) 1368 WP_072175742.1 WalRK two-component regulatory system regulator WalH -
  C2H93_RS18420 (C2H93_18425) walK 3620629..3622464 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42756.50 Da        Isoelectric Point: 5.3354

>NTDB_id=222569 C2H93_RS18400 WP_021481077.1 3616343..3617545(-) (htrA) [Bacillus subtilis strain PK5_16]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=222569 C2H93_RS18400 WP_021481077.1 3616343..3617545(-) (htrA) [Bacillus subtilis strain PK5_16]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTAAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCAGGTACGGAGAGGG
CGATTCCAGTGGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGTGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCGGCGGT
TGAAGGGATTGGCCTGTCGATTCCCTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCTGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTACCGCGGCGGAAAAGAAAAATCTGTAGACATCAAGCTGTCCTCTGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Peptidase family M50 (Peptidase_M50)

(185-395)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.829

99.25

0.435
  htrA Streptococcus gordonii str. Challis substr. CH1

41.542

100

0.417
  htrA Streptococcus mitis NCTC 12261

43.005

96.5

0.415
  htrA Streptococcus pneumoniae TIGR4

45.152

82.5

0.373
  htrA Streptococcus pneumoniae D39

45.152

82.5

0.373
  htrA Streptococcus pneumoniae Rx1

45.152

82.5

0.373
  htrA Streptococcus pneumoniae R6

45.152

82.5

0.373

Multiple sequence alignment