Detailed information NTG0222177

Bioinformatically predicted

Overview

• Name: comQ
• Type: Regulator
• Locus tag: C2H94_RS05340
• Genome accession: NZ_CP026034
• Coordinates: 960154..961014 (-)
• Length: 286 a.a.
• NCBI ID: WP_032677058.1
• Uniprot ID: C0JBN8
• Organism: Bacillus subtilis strain PK5_52
• Function: modification of ComX; production of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 955154..966014

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2H94_RS05305 (C2H94_05270)	mrpE	955393..955869 (+)	477	WP_003228815.1	Na+/H+ antiporter subunit E	-
C2H94_RS05310 (C2H94_05275)	mrpF	955869..956153 (+)	285	WP_003228814.1	Na(+)/H(+) antiporter subunit F1	-
C2H94_RS05315 (C2H94_05280)	mnhG	956137..956511 (+)	375	WP_014477830.1	monovalent cation/H(+) antiporter subunit G	-
C2H94_RS05320 (C2H94_05285)	yuxO	956550..956930 (-)	381	WP_017695528.1	hotdog fold thioesterase	-
C2H94_RS05325 (C2H94_05290)	comA	956949..957593 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
C2H94_RS05330 (C2H94_05295)	-	957674..959970 (-)	2297	Protein_1036	histidine kinase	-
C2H94_RS05335 (C2H94_05300)	comX	959978..960139 (-)	162	WP_049140565.1	competence pheromone ComX	-
C2H94_RS05340 (C2H94_05305)	comQ	960154..961014 (-)	861	WP_032677058.1	polyprenyl synthetase family protein	Regulator
C2H94_RS05345 (C2H94_05310)	degQ	961199..961339 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
C2H94_RS05350	-	961561..961623 (+)	63	Protein_1040	hypothetical protein	-
C2H94_RS05355 (C2H94_05315)	-	961802..962170 (+)	369	WP_017695529.1	hypothetical protein	-
C2H94_RS05360 (C2H94_05320)	pdeH	962146..963375 (-)	1230	WP_003243525.1	cyclic di-GMP phosphodiesterase	-
C2H94_RS05365 (C2H94_05325)	pncB	963512..964984 (-)	1473	WP_003228788.1	nicotinate phosphoribosyltransferase	-
C2H94_RS05370 (C2H94_05330)	pncA	965000..965551 (-)	552	WP_014477836.1	isochorismatase family cysteine hydrolase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 32483.40 Da
• Isoelectric Point: 4.6790

>NTDB_id=222177 C2H94_RS05340 WP_032677058.1 960154..961014(-) (comQ) [Bacillus subtilis strain PK5_52]
MKEIVSQKIMNQDLERYLQNFIESKDTFEFADLALHHYLAFNGQDQKAIELLAAGIELLILSFDIYDDLEDQDNGSAVWM
KIDSSIALNAVTALYTLSIQVMCQASHEPEFSQEILNFALQSIQGQHDDIVNAPQTEEACLEMIKNKSGALTALPCVMGV
MLATGKYHPIVASYSYELGIISQIDNDYKGLFYLNNDFVQKKNTLAYLYLKKQFNDASAELLSLYQKPEEFVSINTKALK
RKLTEAGVIQYLLVMKHLSLQKIKNEMSQLKLEEDKTEKLLSVMIK

Nucleotide

• Length: 861 bp

>NTDB_id=222177 C2H94_RS05340 WP_032677058.1 960154..961014(-) (comQ) [Bacillus subtilis strain PK5_52]
ATGAAGGAGATTGTAAGCCAAAAAATAATGAATCAGGACTTGGAACGATATCTTCAGAATTTTATTGAGTCTAAGGATAC
GTTTGAGTTTGCCGATTTGGCTCTTCATCATTATTTAGCTTTTAACGGTCAGGACCAAAAAGCAATCGAATTGCTAGCTG
CCGGAATTGAATTGCTTATACTCTCATTCGATATTTATGATGACTTAGAGGATCAAGATAATGGAAGTGCTGTCTGGATG
AAGATTGACTCGTCAATCGCTTTAAATGCAGTTACAGCTCTTTACACCCTAAGTATACAAGTGATGTGTCAAGCTAGTCA
TGAACCAGAATTTTCACAAGAGATATTGAATTTTGCGTTACAATCAATTCAAGGCCAGCATGATGATATTGTGAATGCGC
CGCAAACGGAAGAAGCCTGTCTTGAAATGATCAAAAATAAATCAGGAGCGCTAACGGCATTGCCCTGTGTAATGGGAGTA
ATGCTGGCAACAGGCAAATACCATCCCATTGTAGCTTCATATTCTTATGAACTTGGGATTATTTCACAGATCGATAATGA
TTATAAAGGTTTGTTTTACTTAAATAACGATTTTGTTCAGAAAAAAAATACATTGGCATACTTATACTTAAAGAAACAAT
TTAACGATGCTTCAGCGGAGCTACTAAGTTTATATCAAAAACCAGAGGAATTTGTTTCTATTAATACTAAGGCTTTGAAG
CGAAAATTGACAGAAGCAGGCGTTATACAATATTTACTGGTGATGAAACATTTATCTCTCCAAAAAATAAAAAATGAAAT
GTCACAATTAAAACTAGAAGAAGATAAAACTGAAAAATTATTGTCTGTTATGATTAAATAA

Domains

Predicted by InterProScan.

• Polyprenyl synthetase (polyprenyl_synt) (39-229)

3D structure

• AlphaFold DB: C0JBN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comQ	Bacillus subtilis subsp. subtilis str. 168	44.84	98.252	0.441