Detailed information NTG0221593

Bioinformatically predicted

Overview

• Name: crp
• Type: Regulator
• Locus tag: CYK57_RS11030
• Genome accession: NZ_CP026009
• Coordinates: 2329092..2329766 (-)
• Length: 224 a.a.
• NCBI ID: WP_005599747.1
• Uniprot ID: -
• Organism: Actinobacillus pleuropneumoniae strain App6
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2324092..2334766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CYK57_RS11000 (CYK57_02253)	adhP	2324181..2325230 (+)	1050	WP_005602862.1	alcohol dehydrogenase AdhP	-
CYK57_RS11005 (CYK57_02255)	miaA	2325362..2326306 (+)	945	WP_009874864.1	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	-
CYK57_RS11010 (CYK57_02256)	hfq	2326371..2326649 (+)	279	WP_005599741.1	RNA chaperone Hfq	-
CYK57_RS11015 (CYK57_02257)	hflX	2326687..2328054 (+)	1368	WP_080512818.1	ribosome rescue GTPase HflX	-
CYK57_RS11020 (CYK57_02258)	-	2328090..2328650 (-)	561	WP_005606066.1	TIGR00730 family Rossman fold protein	-
CYK57_RS11025 (CYK57_02259)	-	2328713..2329036 (+)	324	WP_005606068.1	MazG-like family protein	-
CYK57_RS11030 (CYK57_02260)	crp	2329092..2329766 (-)	675	WP_005599747.1	cAMP-activated global transcriptional regulator CRP	Regulator
CYK57_RS11035 (CYK57_02261)	-	2329844..2330062 (-)	219	WP_005599748.1	YheU family protein	-
CYK57_RS11040 (CYK57_02262)	slmA	2330068..2330676 (-)	609	WP_005620316.1	nucleoid occlusion factor SlmA	-
CYK57_RS11045 (CYK57_02264)	dut	2330782..2331237 (-)	456	WP_005606071.1	dUTP diphosphatase	-
CYK57_RS11050 (CYK57_02265)	coaBC	2331246..2332451 (-)	1206	WP_005602882.1	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	-
CYK57_RS11055 (CYK57_02266)	radC	2332659..2333321 (+)	663	WP_005599756.1	DNA repair protein RadC	Machinery gene
CYK57_RS11060 (CYK57_02267)	rpmB	2333490..2333726 (+)	237	WP_005599762.1	50S ribosomal protein L28	-
CYK57_RS11065 (CYK57_02268)	rpmG	2333738..2333908 (+)	171	WP_005599764.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25147.02 Da
• Isoelectric Point: 6.5834

>NTDB_id=221593 CYK57_RS11030 WP_005599747.1 2329092..2329766(-) (crp) [Actinobacillus pleuropneumoniae strain App6]
MQDISISTPQLDSELSAPSIHDPAVEWFLTHCHIHRYPSKYTLIHAGEDAESLFYIVSGSVAVFIKDEEGKEMILSHLGQ
GEFVGEISLFEDTIQPRTAWVKTKGACEIAEISYKKFKQLVHLNPDILMYLSAQMARRLRQTSRQVSNLAFLDVTGRIAQ
TLMNLAKMPDAMTHPEGMQIKITRQEIGQMVGCSRETVGRILKMLEDEGLISAHGKTIVVYGTR

Nucleotide

• Length: 675 bp

>NTDB_id=221593 CYK57_RS11030 WP_005599747.1 2329092..2329766(-) (crp) [Actinobacillus pleuropneumoniae strain App6]
ATGCAAGATATTTCAATTTCAACACCTCAGCTAGACAGTGAGCTGTCCGCCCCGTCTATTCATGATCCGGCGGTGGAATG
GTTTCTGACTCACTGTCATATTCATCGTTATCCGTCAAAATATACGCTTATTCATGCGGGTGAGGATGCCGAATCATTAT
TCTATATCGTCAGCGGCTCCGTTGCAGTGTTTATTAAAGATGAAGAAGGGAAAGAAATGATCCTTTCTCACCTCGGTCAA
GGTGAATTTGTCGGTGAAATCAGTTTATTCGAAGACACTATTCAACCGCGTACCGCTTGGGTCAAAACCAAAGGCGCTTG
CGAAATTGCGGAAATCTCGTATAAAAAATTCAAACAGCTTGTGCATTTAAATCCGGATATTCTTATGTATCTTTCCGCAC
AAATGGCTCGCCGCCTACGCCAAACCTCACGCCAAGTAAGTAACCTCGCTTTCTTAGACGTAACCGGTCGTATCGCACAA
ACCTTAATGAATCTGGCAAAAATGCCGGATGCAATGACCCACCCTGAAGGAATGCAAATTAAGATTACCCGCCAAGAAAT
CGGTCAAATGGTCGGTTGTTCTCGAGAAACGGTCGGTAGAATCTTAAAAATGCTAGAAGATGAAGGCTTAATTTCAGCAC
ACGGTAAAACCATTGTCGTTTATGGCACTCGCTAA

Domains

Predicted by InterProScan.

• Crp-like helix-turn-helix domain (HTH_Crp_2) (156-220)

• Cyclic nucleotide-binding domain (cNMP_binding) (36-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
crp	Vibrio cholerae strain A1552	77.34	90.625	0.701
crp	Haemophilus influenzae Rd KW20	73.892	90.625	0.67
crp	Acinetobacter baumannii D1279779	45.794	95.536	0.437