Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   CXX15_RS06490 Genome accession   NZ_CP025847
Coordinates   1316384..1317016 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain 602354     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1311384..1322016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CXX15_RS06465 yheS 1311553..1313466 (+) 1914 WP_000634798.1 ABC transporter ATP-binding protein -
  CXX15_RS06470 yheT 1313466..1314488 (+) 1023 WP_000057405.1 hydrolase -
  CXX15_RS06475 yheU 1314482..1314700 (+) 219 WP_000907085.1 YheU family protein -
  CXX15_RS06480 prkB 1314754..1315623 (+) 870 WP_001274680.1 phosphoribulokinase -
  CXX15_RS06485 yhfA 1315678..1316082 (-) 405 WP_001148908.1 OsmC family protein -
  CXX15_RS06490 crp 1316384..1317016 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  CXX15_RS06495 yhfK 1317067..1319157 (+) 2091 WP_001345983.1 YccS/YhfK family putative transporter -
  CXX15_RS06500 argD 1319224..1320444 (-) 1221 WP_129547499.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  CXX15_RS06505 pabA 1320530..1321093 (-) 564 WP_000601844.1 aminodeoxychorismate synthase component 2 -
  CXX15_RS06510 fic 1321125..1321727 (-) 603 WP_001280624.1 putative adenosine monophosphate-protein transferase Fic -
  CXX15_RS06515 yhfG 1321717..1321884 (-) 168 WP_000736860.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=220092 CXX15_RS06490 WP_000242755.1 1316384..1317016(+) (crp) [Escherichia coli strain 602354]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=220092 CXX15_RS06490 WP_000242755.1 1316384..1317016(+) (crp) [Escherichia coli strain 602354]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTTCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467

Multiple sequence alignment