Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BV139_RS02005 Genome accession   NZ_CP020012
Coordinates   416905..418122 (-) Length   405 a.a.
NCBI ID   WP_005686722.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 6P24H2     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 411905..423122
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV139_RS01965 (BV139_401) - 412790..412996 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  BV139_RS01970 (BV139_402) - 413070..413276 (-) 207 WP_005631184.1 heavy-metal-associated domain-containing protein -
  BV139_RS01975 (BV139_403) - 413361..413567 (-) 207 WP_015701556.1 heavy-metal-associated domain-containing protein -
  BV139_RS01980 (BV139_404) - 413652..413858 (-) 207 WP_005686717.1 heavy-metal-associated domain-containing protein -
  BV139_RS01985 (BV139_405) cueR 413935..414321 (+) 387 WP_005663006.1 Cu(I)-responsive transcriptional regulator -
  BV139_RS01990 (BV139_406) metJ 414335..414652 (-) 318 WP_005634287.1 met regulon transcriptional regulator MetJ -
  BV139_RS01995 (BV139_407) rho 414900..416162 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  BV139_RS02000 (BV139_408) pilD 416216..416908 (-) 693 WP_005686720.1 prepilin peptidase Machinery gene
  BV139_RS02005 (BV139_409) pilC 416905..418122 (-) 1218 WP_005686722.1 type II secretion system F family protein Machinery gene
  BV139_RS02010 (BV139_410) pilB 418119..419516 (-) 1398 WP_005686724.1 GspE/PulE family protein Machinery gene
  BV139_RS02015 (BV139_411) pilA 419513..419962 (-) 450 WP_005686726.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  BV139_RS02020 (BV139_412) ampD 420077..420637 (+) 561 WP_005686728.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  BV139_RS02025 (BV139_413) corC 421258..422157 (+) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46122.32 Da        Isoelectric Point: 9.7232

>NTDB_id=219966 BV139_RS02005 WP_005686722.1 416905..418122(-) (pilC) [Haemophilus influenzae strain 6P24H2]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRELTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSAIPLKNSL
QILQQNCTQIMLNEWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYFYLKRQIWF
HQKKNQLISVTPIFGTIQKLSRLVNFSQSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSNSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=219966 BV139_RS02005 WP_005686722.1 416905..418122(-) (pilC) [Haemophilus influenzae strain 6P24H2]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCACACTTTCAGTTAATAAGCCGCGAGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAGC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGCAATTCCGTTAAAAAACAGCCTG
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACGAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCAATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGCCAATCTTTAGCATTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTGCCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTTCTATCTAAAACGCCAGATCTGGTTT
CATCAAAAGAAAAATCAACTTATCTCTGTCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCAAAGTTTACAAATTATGTTGCAGGCCGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTTCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTGCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTAATAGCGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAGGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.291

100

0.975
  pilC Haemophilus influenzae Rd KW20

97.044

100

0.973
  pilC Glaesserella parasuis strain SC1401

38.25

98.765

0.378

Multiple sequence alignment