Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   BV121_RS01625 Genome accession   NZ_CP020008
Coordinates   336145..337362 (-) Length   405 a.a.
NCBI ID   WP_105182543.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 5P28H1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 331145..342362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV121_RS01585 (BV121_322) - 332040..332246 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  BV121_RS01590 (BV121_323) - 332320..332526 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  BV121_RS01595 (BV121_324) - 332600..332806 (-) 207 WP_005666693.1 heavy-metal-associated domain-containing protein -
  BV121_RS01600 (BV121_325) - 332892..333098 (-) 207 WP_005666692.1 heavy-metal-associated domain-containing protein -
  BV121_RS01605 (BV121_326) cueR 333175..333561 (+) 387 WP_005648963.1 Cu(I)-responsive transcriptional regulator -
  BV121_RS01610 (BV121_327) metJ 333575..333892 (-) 318 WP_005631186.1 met regulon transcriptional regulator MetJ -
  BV121_RS01615 (BV121_328) rho 334140..335402 (+) 1263 WP_005648966.1 transcription termination factor Rho -
  BV121_RS01620 (BV121_329) pilD 335456..336148 (-) 693 WP_014550482.1 prepilin peptidase Machinery gene
  BV121_RS01625 (BV121_330) pilC 336145..337362 (-) 1218 WP_105182543.1 type II secretion system F family protein Machinery gene
  BV121_RS01630 (BV121_331) pilB 337359..338753 (-) 1395 WP_011271972.1 GspE/PulE family protein Machinery gene
  BV121_RS01635 (BV121_332) pilA 338750..339199 (-) 450 WP_105182544.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  BV121_RS01640 (BV121_333) ampD 339314..339874 (+) 561 WP_042599472.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  BV121_RS01645 (BV121_334) corC 340487..341386 (+) 900 WP_005656283.1 CNNM family magnesium/cobalt transport protein CorC -

Sequence

Protein


Download         Length: 405 a.a.        Molecular weight: 46045.30 Da        Isoelectric Point: 9.8175

>NTDB_id=219825 BV121_RS01625 WP_105182543.1 336145..337362(-) (pilC) [Haemophilus influenzae strain 5P28H1]
MTKKLFYYQGSNALNQKQKGSIIADTKQQAHFQLISRGLTHIKLQQNWQFGAKPKNSEISELLNQLATLLQSVIPLKNSL
QILQQNCTQIMLNKWLERLLQSIESGLAFSQAIEQQGKYLTQQEIQLIQVGEMTGKLAVVCKKIATHRSQSLALQRKLQK
IMLYPSMVLGISLLLTLALLLFIVPQFAEMYSGNNAELPTITAILLSISNFLKQNIGILLFFALSFVLFYYCYLKRQTWF
HQKKNQLISITPIFGTIQKLSRLVNFSHSLQIMLQAGVPLNQALDSFLPRTQTWQTKTLVNDIILDKEVRSILQWVSQGY
AFSDSVSSDLFPMEAQQMLQIGEQSGKLALMLEHIADNYQEKLNHQIDLLSQMLEPLMMVIIGSLIGIIMMGMYLPIFNM
GSVIQ

Nucleotide


Download         Length: 1218 bp        

>NTDB_id=219825 BV121_RS01625 WP_105182543.1 336145..337362(-) (pilC) [Haemophilus influenzae strain 5P28H1]
ATGACTAAAAAACTCTTTTATTATCAAGGTAGTAACGCATTAAATCAGAAACAAAAAGGCTCAATTATTGCGGATACGAA
ACAACAAGCGCACTTTCAGTTAATAAGCCGCGGGCTTACTCACATCAAATTACAACAAAACTGGCAATTTGGGGCAAAAC
CCAAAAATTCAGAAATCAGTGAATTACTCAATCAATTAGCGACATTGCTACAGTCCGTAATTCCGTTAAAAAACAGCCTA
CAAATTTTGCAACAAAATTGTACTCAAATTATGCTCAACAAATGGCTTGAACGACTGCTTCAATCCATTGAATCTGGCTT
AGCATTCTCACAAGCCATTGAACAACAAGGAAAATATCTCACACAACAAGAAATTCAACTGATTCAAGTGGGAGAAATGA
CAGGAAAACTTGCCGTAGTTTGTAAAAAAATAGCCACGCACCGTAGTCAATCTTTGGCTTTACAACGCAAATTACAGAAA
ATTATGTTATATCCCTCAATGGTATTGGGAATTTCTCTATTATTGACACTCGCATTACTGCTTTTTATCGTACCTCAATT
TGCTGAAATGTACAGTGGCAACAATGCCGAATTACCAACAATAACTGCAATATTGCTCTCTATATCCAATTTTCTTAAGC
AAAATATTGGCATTTTGCTATTTTTCGCTTTGAGTTTTGTTCTATTTTATTACTGTTATCTAAAACGCCAGACTTGGTTT
CATCAAAAGAAAAATCAACTTATTTCTATCACGCCTATTTTTGGCACAATTCAAAAACTTTCACGTTTAGTGAACTTTAG
TCACAGTTTACAAATTATGTTACAGGCTGGCGTACCGCTTAATCAAGCACTAGACAGTTTTCTCCCTCGCACACAAACGT
GGCAAACCAAGACGCTTGTAAATGACATCATATTAGATAAAGAAGTCCGGTCAATTTTACAATGGGTTTCTCAAGGCTAT
GCGTTTTCTGATAGTGTAAGTAGCGATCTTTTCCCGATGGAAGCACAACAAATGTTACAAATTGGCGAGCAAAGCGGAAA
ACTCGCTTTGATGCTAGAGCATATTGCGGATAATTACCAAGAAAAACTTAATCATCAAATTGACTTACTCTCACAAATGC
TAGAACCATTAATGATGGTAATTATCGGCAGTCTGATTGGAATTATTATGATGGGAATGTATTTACCTATCTTTAATATG
GGCTCTGTTATTCAATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(266-396)

Type II secretion system (T2SS), protein F (T2SSF)

(63-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Haemophilus influenzae 86-028NP

97.783

100

0.98
  pilC Haemophilus influenzae Rd KW20

96.552

100

0.968
  pilC Glaesserella parasuis strain SC1401

38.5

98.765

0.38

Multiple sequence alignment