Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   LLG50_RS02030 Genome accession   NZ_CP025500
Coordinates   406061..407503 (-) Length   480 a.a.
NCBI ID   WP_010905315.1    Uniprot ID   Q9CIG6
Organism   Lactococcus lactis subsp. lactis strain G50     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 401061..412503
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLG50_RS02005 (LLG50_02005) nox 401095..402435 (+) 1341 WP_058219163.1 H2O-forming NADH oxidase -
  LLG50_RS02010 (LLG50_02010) - 402524..402913 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  LLG50_RS02015 (LLG50_02015) groES 403033..403317 (+) 285 WP_003131589.1 co-chaperone GroES -
  LLG50_RS02020 (LLG50_02020) groL 403405..405033 (+) 1629 WP_058206244.1 chaperonin GroEL -
  LLG50_RS02025 (LLG50_02025) vicX 405078..405890 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  LLG50_RS02030 (LLG50_02030) vicK 406061..407503 (-) 1443 WP_010905315.1 sensor histidine kinase Regulator
  LLG50_RS02035 (LLG50_02035) yycF 407496..408197 (-) 702 WP_003131580.1 response regulator YycF -
  LLG50_RS02040 (LLG50_02040) tmk 408375..409010 (+) 636 WP_103054462.1 dTMP kinase -
  LLG50_RS02045 (LLG50_02045) - 409143..410003 (+) 861 WP_057719679.1 DNA polymerase III subunit delta' -
  LLG50_RS02050 (LLG50_02050) yaaT 410055..410837 (+) 783 WP_010905316.1 PSP1 domain-containing protein Regulator
  LLG50_RS02055 (LLG50_02055) yabA 410830..411156 (+) 327 WP_003131570.1 DNA replication initiation control protein YabA -
  LLG50_RS02060 (LLG50_02060) rsmI 411156..412031 (+) 876 WP_103054463.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  LLG50_RS02065 (LLG50_02065) - 412108..412299 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54695.14 Da        Isoelectric Point: 4.5889

>NTDB_id=219151 LLG50_RS02030 WP_010905315.1 406061..407503(-) (vicK) [Lactococcus lactis subsp. lactis strain G50]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIVKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=219151 LLG50_RS02030 WP_010905315.1 406061..407503(-) (vicK) [Lactococcus lactis subsp. lactis strain G50]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCCCACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGTGATAAAATC
CCAAAAGGGACAAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTCGGTGAAGATATTGTTCGCACACAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGATAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGGATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
TATTGTCCATGATATTGTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

PAS domain (PAS_9)

(124-220)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9CIG6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.559

86.875

0.448
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442

Multiple sequence alignment