Detailed information NTG0218710

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: B2G52_RS00565
• Genome accession: NZ_CP019894
• Coordinates: 102775..103635 (+)
• Length: 286 a.a.
• NCBI ID: WP_003710975.1
• Uniprot ID: A0A1V0DRE8
• Organism: Neisseria lactamica strain Y92-1009
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 97775..108635

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
B2G52_RS00545 (B2G52_00545)	dapD	98441..99262 (-)	822	WP_003713998.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
B2G52_RS00550 (B2G52_00550)	-	99272..99502 (-)	231	WP_078835829.1	hypothetical protein	-
B2G52_RS00555 (B2G52_00555)	pgi	99472..101115 (-)	1644	WP_003714000.1	glucose-6-phosphate isomerase	-
B2G52_RS00560 (B2G52_00560)	pilG	101469..102701 (+)	1233	WP_003710974.1	type 4 pilus assembly protein PilG	Machinery gene
B2G52_RS00565 (B2G52_00565)	pilD	102775..103635 (+)	861	WP_003710975.1	prepilin peptidase	Machinery gene
B2G52_RS00570 (B2G52_00570)	coaE	103637..104269 (+)	633	WP_003714003.1	dephospho-CoA kinase	-
B2G52_RS00575 (B2G52_00575)	-	104262..104471 (+)	210	WP_019272186.1	DNA gyrase inhibitor YacG	-
B2G52_RS00580 (B2G52_00580)	pilF	104556..106232 (-)	1677	WP_003714005.1	type IV-A pilus assembly ATPase PilB	Machinery gene
B2G52_RS00585 (B2G52_00585)	-	106480..106686 (-)	207	WP_003714007.1	hypothetical protein	-
B2G52_RS00595 (B2G52_00595)	-	106867..107313 (-)	447	WP_003714009.1	DUF441 domain-containing protein	-
B2G52_RS00600 (B2G52_00600)	-	107318..108292 (-)	975	WP_003714011.1	polyprenyl synthetase family protein	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31231.27 Da
• Isoelectric Point: 8.7141

>NTDB_id=218710 B2G52_RS00565 WP_003710975.1 102775..103635(+) (pilD) [Neisseria lactamica strain Y92-1009]
MFALSVLPPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPSIELLTGVLFGLVAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=218710 B2G52_RS00565 WP_003710975.1 102775..103635(+) (pilD) [Neisseria lactamica strain Y92-1009]
ATGTTTGCTTTATCTGTACTGCCTCCGTTTGCCGTACCTTTGGCAGCGGTGTTGGGACTGCTGGTCGGCAGTTTCCTGAA
TGTTGTCATTTACCGCGTACCCGTGATGATGGAGCGCGGTTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGATGAGGAAAGCCGCACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCGAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCCTCCTGCCAAACCAAAATCAGCATACGCTACCC
CTCTATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATTTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCATTATGGCTCTTATGTGCGGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCAGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

3D structure

• AlphaFold DB: A0A1V0DRE8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	97.193	99.65	0.969
pilD	Acinetobacter baumannii D1279779	48.485	92.308	0.448
pilD	Acinetobacter nosocomialis M2	48.485	92.308	0.448
pilD	Vibrio campbellii strain DS40M4	44.251	100	0.444
pilD	Vibrio cholerae strain A1552	46.014	96.503	0.444