Detailed information    

insolico Bioinformatically predicted

Overview

Name   degS   Type   Regulator
Locus tag   BZ167_RS12440 Genome accession   NZ_CP019626
Coordinates   2568682..2569845 (+) Length   387 a.a.
NCBI ID   WP_007407484.1    Uniprot ID   A3KLC1
Organism   Bacillus sp. 275     
Function   phosphorylation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2563682..2574845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZ167_RS12420 (BZ167_12465) - 2564089..2565285 (+) 1197 WP_060673980.1 glycosyltransferase -
  BZ167_RS12425 (BZ167_12470) - 2565418..2566494 (+) 1077 WP_003151382.1 MraY family glycosyltransferase -
  BZ167_RS12430 (BZ167_12475) - 2566593..2567807 (-) 1215 WP_015418337.1 LCP family protein -
  BZ167_RS12435 (BZ167_12480) - 2567812..2568459 (-) 648 WP_007407485.1 YigZ family protein -
  BZ167_RS12440 (BZ167_12485) degS 2568682..2569845 (+) 1164 WP_007407484.1 two-component sensor histidine kinase DegS Regulator
  BZ167_RS12445 (BZ167_12490) degU 2569922..2570611 (+) 690 WP_061860922.1 two-component system response regulator DegU Regulator
  BZ167_RS12450 (BZ167_12495) - 2570709..2571557 (+) 849 WP_061860921.1 DegV family protein -
  BZ167_RS12455 (BZ167_12500) comFA 2571665..2573050 (+) 1386 WP_061860920.1 DEAD/DEAH box helicase Machinery gene
  BZ167_RS12460 (BZ167_12505) - 2573108..2573392 (+) 285 WP_003151389.1 competence protein ComFB -
  BZ167_RS20610 - 2573410..2573568 (+) 159 Protein_2394 double zinc ribbon domain-containing protein -
  BZ167_RS12465 (BZ167_12510) comFC 2573611..2574087 (+) 477 WP_269465503.1 phosphoribosyltransferase family protein Machinery gene
  BZ167_RS12470 (BZ167_12515) - 2574161..2574580 (+) 420 WP_025285352.1 TIGR03826 family flagellar region protein -

Sequence

Protein


Download         Length: 387 a.a.        Molecular weight: 45014.78 Da        Isoelectric Point: 6.8616

>NTDB_id=217362 BZ167_RS12440 WP_007407484.1 2568682..2569845(+) (degS) [Bacillus sp. 275]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide


Download         Length: 1164 bp        

>NTDB_id=217362 BZ167_RS12440 WP_007407484.1 2568682..2569845(+) (degS) [Bacillus sp. 275]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGTGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATTATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(291-384)

Sensor protein DegS (DegS)

(12-170)

Histidine kinase (HisKA_3)

(180-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A3KLC1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  degS Bacillus subtilis subsp. subtilis str. 168

95.584

99.483

0.951

Multiple sequence alignment