Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   BWR56_RS04935 Genome accession   NZ_CP019562
Coordinates   1021131..1022480 (-) Length   449 a.a.
NCBI ID   WP_049505845.1    Uniprot ID   -
Organism   Streptococcus oralis strain S.MIT/ORALIS-351     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1016131..1027480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWR56_RS04915 (BWR56_0975) - 1017244..1018962 (+) 1719 WP_076984560.1 phospho-sugar mutase -
  BWR56_RS04920 (BWR56_0976) - 1019074..1019421 (+) 348 WP_076984561.1 PedC/BrcD family bacteriocin maturation disulfide isomerase -
  BWR56_RS04925 (BWR56_0977) - 1019459..1020232 (-) 774 WP_076984562.1 potassium channel family protein -
  BWR56_RS04930 (BWR56_0978) vicX 1020320..1021129 (-) 810 WP_049505844.1 MBL fold metallo-hydrolase Regulator
  BWR56_RS04935 (BWR56_0979) micB 1021131..1022480 (-) 1350 WP_049505845.1 cell wall metabolism sensor histidine kinase VicK Regulator
  BWR56_RS04940 (BWR56_0980) micA 1022473..1023180 (-) 708 WP_049505846.1 response regulator YycF Regulator
  BWR56_RS04945 (BWR56_0981) mutY 1023237..1024415 (-) 1179 WP_049505847.1 A/G-specific adenine glycosylase -
  BWR56_RS04950 (BWR56_0982) pta 1024498..1025472 (-) 975 WP_076984563.1 phosphate acetyltransferase -
  BWR56_RS04955 (BWR56_0983) - 1025516..1026412 (-) 897 WP_049505849.1 RluA family pseudouridine synthase -
  BWR56_RS04960 (BWR56_0984) - 1026409..1027227 (-) 819 WP_000799063.1 NAD kinase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51634.03 Da        Isoelectric Point: 4.5770

>NTDB_id=216323 BWR56_RS04935 WP_049505845.1 1021131..1022480(-) (micB) [Streptococcus oralis strain S.MIT/ORALIS-351]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKEINQKVKDLIAGDYSQVLDLQGSTEITNITNNLNDLSE
VIRLTQENLEQESKRLNSILSYMTDGVLATNRRGQIIMINDMAKKQLGVQKEDVLNKSILELLKIEDEYELRDLITQIPE
LTIDSQDVNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPIAPDFIKVSLDETNRMMRMVTDLLHLSRIDNTTSQLDVELINFTAFITFILNRFDKMRSQDDEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEIWEDEIED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=216323 BWR56_RS04935 WP_049505845.1 1021131..1022480(-) (micB) [Streptococcus oralis strain S.MIT/ORALIS-351]
ATGATTGAAGATATTAGACAAACTATTCTGACCAGCGATTTTATCTTTATCTTGATTTTACTTGGCTTTATCCTGGTGGT
GACCTTGCTGTTACTGGAAAATCGTCGGGATAATATCCGTCTGAAGGAGATAAATCAAAAGGTTAAGGACTTGATTGCAG
GTGATTATTCTCAAGTTTTGGACTTGCAAGGAAGTACAGAAATCACCAATATCACCAATAATCTGAACGATTTGTCAGAA
GTTATTCGTTTGACCCAAGAAAATCTGGAACAAGAGAGTAAACGATTGAACAGTATTCTTTCTTACATGACAGATGGCGT
TCTTGCGACTAATCGCCGTGGTCAGATTATTATGATTAACGATATGGCAAAGAAACAGCTCGGTGTGCAGAAAGAAGATG
TTCTGAATAAAAGCATCCTCGAATTGCTTAAGATAGAAGATGAGTATGAGCTGCGTGATCTGATTACACAGATTCCTGAG
TTGACGATTGACTCCCAGGATGTAAATGGGGAATACCTAAGCCTTCGTGTCCGTTTTGCTCTGGTTCGCCGTGAGTCAGG
TTTCATCTCTGGTTTGGTTGCCGTTTTACATGATACGACCGAGCAGGAGAAGGAAGAACGTGAGCGGAGACTCTTCGTTT
CAAACGTAAGTCATGAGTTAAGAACTCCTTTGACCAGTGTAAAATCTTATCTTGAAGCCTTGGACGAGGGAGCCTTGTAT
GATCCCATTGCCCCTGATTTTATCAAGGTTTCACTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATACGACAAGTCAGCTAGATGTGGAACTGATTAATTTTACAGCTTTCATCACATTTATTCTCA
ACCGCTTTGATAAGATGAGAAGTCAAGATGACGAGAAAAAATATGAACTTGTTAGAGATTACCCTATTAATTCAGTTTGG
ATCGAGATTGATACCGATAAGATGACTCAAGTGATTGATAACATTCTTAACAATGCCATTAAGTACTCACCAGATGGTGG
GAAAATCACTGTCAGCATGAAAACCACTGACGACCAGATGATTTTATCCATCAAAGACCAAGGTCTAGGTATTCCAAAGC
AAGATTTGCCGAAGATCTTTGACCGCTTCTACCGTGTGGATCGTGCAAGAAGCCGGGCTCAAGGTGGAACTGGTCTAGGT
CTGGCTATCGCAAAAGAAATCATTAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGATCGACCTT
TACCATAGTGCTCCCTTATGATAAGGATGCCGTAAAAGAAGAAATATGGGAGGACGAAATAGAAGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.294

97.773

0.873
  vicK Streptococcus mutans UA159

70.398

89.532

0.63

Multiple sequence alignment