Detailed information NTG0216258

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: CWQ22_RS01070
• Genome accession: NZ_CP025027
• Coordinates: 176068..176529 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874812.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain SGEHI2015-107
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 171068..181529

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CWQ22_RS01035 (CWQ22_01035)	-	172683..173048 (+)	366	WP_000285373.1	DUF1033 family protein	-
CWQ22_RS01045 (CWQ22_01045)	comGA	173221..174192 (+)	972	WP_000250805.1	competence type IV pilus ATPase ComGA	Machinery gene
CWQ22_RS01050 (CWQ22_01050)	comGB	174086..175129 (+)	1044	WP_223295889.1	competence type IV pilus assembly protein ComGB	Machinery gene
CWQ22_RS01055 (CWQ22_01055)	comGC/cglC	175126..175455 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
CWQ22_RS01060 (CWQ22_01060)	comGD	175430..175843 (+)	414	WP_100880998.1	competence type IV pilus minor pilin ComGD	Machinery gene
CWQ22_RS01065 (CWQ22_01065)	comGE	175815..176114 (+)	300	WP_000234804.1	competence type IV pilus minor pilin ComGE	Machinery gene
CWQ22_RS01070 (CWQ22_01070)	comGF	176068..176529 (+)	462	WP_001874812.1	competence type IV pilus minor pilin ComGF	Machinery gene
CWQ22_RS01075 (CWQ22_01075)	comGG	176507..176878 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
CWQ22_RS01080 (CWQ22_01080)	comGH	176993..177967 (+)	975	WP_001008574.1	N-6 DNA methylase	Machinery gene
CWQ22_RS01085 (CWQ22_01085)	-	177999..179192 (+)	1194	WP_000047534.1	acetate kinase	-
CWQ22_RS01090 (CWQ22_01090)	-	179344..179550 (+)	207	WP_000798241.1	helix-turn-helix transcriptional regulator	-
CWQ22_RS01095 (CWQ22_01095)	-	179609..179746 (+)	138	WP_001865900.1	hypothetical protein	-
CWQ22_RS01100 (CWQ22_01100)	-	179787..180242 (+)	456	WP_000905673.1	hypothetical protein	-
CWQ22_RS01105 (CWQ22_01105)	-	180311..180976 (+)	666	WP_000008113.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17875.89 Da
• Isoelectric Point: 9.8392

>NTDB_id=216258 CWQ22_RS01070 WP_001874812.1 176068..176529(+) (comGF) [Streptococcus agalactiae strain SGEHI2015-107]
MKIIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=216258 CWQ22_RS01070 WP_001874812.1 176068..176529(+) (comGF) [Streptococcus agalactiae strain SGEHI2015-107]
TTGAAGATAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTTGAAGGCGCTCATCTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAGACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373