Detailed information NTG0021615

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: NMB_RS10490
• Genome accession: NC_003112
• Coordinates: 2131086..2131535 (-)
• Length: 149 a.a.
• NCBI ID: WP_002214937.1
• Uniprot ID: A0AA44U8B7
• Organism: Neisseria meningitidis MC58
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2126086..2136535

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMB_RS10475 (NMB2012)	-	2128211..2129302 (-)	1092	WP_002225876.1	XRE family transcriptional regulator	-
NMB_RS10480 (NMB2013)	-	2129318..2129962 (-)	645	WP_002223148.1	hypothetical protein	-
NMB_RS11390	-	2130319..2130471 (+)	153	WP_002223150.1	hypothetical protein	-
NMB_RS12245 (NMB2015)	-	2130728..2130996 (+)	269	Protein_2037	5'-nucleotidase	-
NMB_RS10490 (NMB2016)	comP	2131086..2131535 (-)	450	WP_002214937.1	type IV pilin protein	Machinery gene
NMB_RS10495 (NMB2017)	comE	2131623..2132087 (-)	465	WP_162467384.1	ComEA family DNA-binding protein	Machinery gene

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16834.81 Da
• Isoelectric Point: 9.7951

>NTDB_id=21615 NMB_RS10490 WP_002214937.1 2131086..2131535(-) (comP) [Neisseria meningitidis MC58]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYVEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=21615 NMB_RS10490 WP_002214937.1 2131086..2131535(-) (comP) [Neisseria meningitidis MC58]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATGTTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGGTTTAAACAAACATCTACCAAGTGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCTTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	100	100	1
comP	Neisseria meningitidis 8013	99.329	100	0.993
comP	Neisseria subflava NJ9703	49.66	98.658	0.49