Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   CFP59_RS21990 Genome accession   NZ_CP025018
Coordinates   5333245..5334303 (+) Length   352 a.a.
NCBI ID   WP_069873662.1    Uniprot ID   A0A9X2M0H5
Organism   Streptomyces sp. M56     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 5328245..5339303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFP59_RS21975 (CFP59_04329) - 5328271..5329212 (+) 942 WP_100806584.1 hypothetical protein -
  CFP59_RS21980 (CFP59_04330) - 5329328..5331037 (-) 1710 WP_100806585.1 sigma-70 family RNA polymerase sigma factor -
  CFP59_RS21985 (CFP59_04331) radA/sms 5331238..5332662 (+) 1425 WP_093703699.1 DNA repair protein RadA Machinery gene
  CFP59_RS21990 (CFP59_04332) disA 5333245..5334303 (+) 1059 WP_069873662.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  CFP59_RS21995 (CFP59_04333) - 5334982..5335863 (-) 882 WP_100806586.1 hypothetical protein -
  CFP59_RS22000 (CFP59_04334) - 5336156..5337082 (+) 927 WP_069873517.1 A/G-specific adenine glycosylase -
  CFP59_RS22010 (CFP59_04335) - 5337475..5338086 (+) 612 WP_069873518.1 SigE family RNA polymerase sigma factor -
  CFP59_RS22015 (CFP59_04336) - 5338113..5338802 (+) 690 WP_069873520.1 hypothetical protein -

Sequence

Protein


Download         Length: 352 a.a.        Molecular weight: 38219.98 Da        Isoelectric Point: 5.0869

>NTDB_id=216084 CFP59_RS21990 WP_069873662.1 5333245..5334303(+) (disA) [Streptomyces sp. M56]
MRASLSAVAPGTALRDGLERVLRGNTGGLIVLGTDKTVESLCTGGFVIDVEFTATRLRELCKLDGALVLDKDITKIVRAG
VQLVPDAAIPTEETGTRHRTAQRVSIQTGFPVVSVSQSMRLIALYVDGQRRVLEDSAAILSRANQALATLERYKLRLDEV
AGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIAGVEPERELVVRDYVPEPTAKRT
RTVTDALAELDRLTHAELLELPIVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGAIIERLVEHFGGLQKLLAASVDD
LQMVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1059 bp        

>NTDB_id=216084 CFP59_RS21990 WP_069873662.1 5333245..5334303(+) (disA) [Streptomyces sp. M56]
ATGCGTGCCTCCCTGAGCGCGGTCGCGCCCGGCACGGCGCTGCGCGACGGCCTCGAGCGGGTTCTCCGGGGAAACACCGG
CGGGCTGATCGTGCTCGGCACCGACAAGACCGTCGAGTCGCTGTGTACCGGCGGCTTCGTCATCGACGTCGAGTTCACCG
CGACCCGGCTGCGCGAGCTGTGCAAGCTGGACGGCGCGCTGGTCCTCGACAAGGACATCACCAAGATCGTGCGGGCCGGG
GTGCAGCTGGTGCCCGACGCGGCGATCCCCACCGAGGAGACCGGCACCCGGCACCGCACCGCGCAGCGCGTCTCCATCCA
GACCGGGTTCCCGGTGGTCTCGGTCAGCCAGTCGATGCGGCTGATCGCGCTGTATGTGGACGGTCAGCGGCGGGTCCTGG
AGGATTCGGCGGCGATCCTGTCCCGCGCCAACCAGGCGCTGGCCACGCTGGAGCGCTACAAGCTCCGCCTCGACGAGGTG
GCGGGCACGCTCTCGGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGATGTGAGCGCGGTCGCACAGCGGCTGGAGAT
GGTTCGCCGCATCGCCACCGAGATCGCGGAGTACGTGGTCGAGCTGGGCACCGACGGCCGGCTGCTCTCCCTCCAGCTGG
ACGAGCTGATCGCGGGCGTGGAGCCGGAGCGTGAGCTGGTGGTGCGGGACTACGTCCCCGAGCCGACCGCCAAGCGCACT
CGTACGGTGACCGACGCGCTCGCCGAGCTGGACCGGCTGACCCACGCCGAGCTGCTCGAACTCCCCATCGTGGCCCGGGC
GCTGGGGTACACCGGCTCGCCCGAGACCCTCGACTCGGCGGTCTCGCCGCGCGGCTTCCGGCTGCTGGCGAAGGTGCCGC
GGCTTCCGGGCGCCATCATCGAGCGGCTCGTGGAGCACTTCGGGGGCTTGCAGAAGCTGCTGGCGGCGAGCGTGGACGAC
CTCCAGATGGTGGACGGCGTGGGCGAGGCCCGCGCGCGCTCGGTCCGCGAGGGCCTGTCGCGGCTGGCCGAGTCGTCCAT
CCTGGAGCGGTACGTTTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(133-275)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(16-129)

Helix-hairpin-helix motif (HHH_2)

(302-337)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X2M0H5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

47.11

98.295

0.463

Multiple sequence alignment