Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CU118_RS07255 Genome accession   NZ_CP024998
Coordinates   1429161..1429784 (-) Length   207 a.a.
NCBI ID   WP_054189553.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 55-99-44     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1424161..1434784
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CU118_RS07225 (CU118_07225) - 1424495..1425691 (-) 1197 WP_054189555.1 metallophosphoesterase family protein -
  CU118_RS07230 (CU118_07230) - 1425991..1426086 (-) 96 Protein_1380 hypothetical protein -
  CU118_RS07240 (CU118_07240) - 1426625..1426969 (-) 345 WP_000290301.1 YlbF/YmcA family competence regulator -
  CU118_RS07245 (CU118_07245) - 1427038..1428162 (-) 1125 WP_054189554.1 DUF445 domain-containing protein -
  CU118_RS07250 (CU118_07250) xdrA 1428341..1428805 (-) 465 WP_000375864.1 XRE family transcriptional regulator XdrA -
  CU118_RS07255 (CU118_07255) vraR 1429161..1429784 (-) 624 WP_054189553.1 response regulator Regulator
  CU118_RS07260 (CU118_07260) - 1429806..1430918 (-) 1113 WP_000437962.1 GAF domain-containing sensor histidine kinase -
  CU118_RS07265 (CU118_07265) - 1431081..1431902 (+) 822 WP_054189552.1 RluA family pseudouridine synthase -
  CU118_RS07270 (CU118_07270) fumC 1432369..1433754 (-) 1386 WP_054189551.1 class II fumarate hydratase -
  CU118_RS07275 (CU118_07275) - 1433950..1434345 (-) 396 WP_000901023.1 hypothetical protein -

Sequence

Protein


Download         Length: 207 a.a.        Molecular weight: 23891.57 Da        Isoelectric Point: 5.5730

>NTDB_id=216019 CU118_RS07255 WP_054189553.1 1429161..1429784(-) (vraR) [Staphylococcus aureus strain 55-99-44]
MNKVILVDDHYIVRQGLRFLLSTIENIEVLQDFADGEPFLEYLKEHEHPDIVLLDLVMPGMNGIEITEYIKAHYPDIKVL
VLTSYVDDEHVISAINKGADGYEMKDVEPQQLIETIRRVMNGEKMIHPKAQDVFETVSQKPHYTNKLSKREIEVLREMVK
GKTNKEIAETLFVSEKTIKTHVSHIFSKLQVSDRTQAAIYAMENKLI

Nucleotide


Download         Length: 624 bp        

>NTDB_id=216019 CU118_RS07255 WP_054189553.1 1429161..1429784(-) (vraR) [Staphylococcus aureus strain 55-99-44]
ATGAACAAAGTAATATTAGTAGATGACCATTATATTGTGCGACAAGGATTGCGATTTTTATTATCCACCATTGAAAACAT
TGAAGTTTTACAAGATTTTGCAGATGGAGAACCATTTTTAGAATATTTAAAAGAGCATGAGCACCCTGATATTGTGCTAT
TAGATTTAGTGATGCCTGGCATGAATGGTATTGAAATTACGGAATATATTAAGGCACATTATCCGGATATTAAAGTTTTG
GTATTAACAAGTTATGTTGATGATGAGCATGTAATTTCAGCAATCAATAAAGGTGCTGATGGTTATGAAATGAAAGACGT
TGAGCCTCAGCAATTAATTGAAACTATTAGACGAGTTATGAACGGTGAAAAAATGATACATCCTAAGGCACAAGATGTAT
TCGAAACAGTTAGCCAAAAACCACACTACACGAATAAGTTGTCAAAGAGAGAAATTGAAGTGCTACGTGAAATGGTTAAA
GGTAAAACAAATAAAGAGATAGCAGAAACTTTATTTGTATCTGAAAAAACAATTAAAACACATGTCAGTCATATATTTAG
TAAATTACAAGTTAGCGATCGTACACAAGCAGCAATTTATGCAATGGAAAATAAGTTGATTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-201)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

40.58

100

0.406
  degU Bacillus subtilis subsp. subtilis str. 168

35.135

100

0.377
  letA Legionella pneumophila str. Paris

35.714

100

0.362
  letA Legionella pneumophila strain ERS1305867

35.714

100

0.362

Multiple sequence alignment