Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   SPY_RS00630 Genome accession   NC_002737
Coordinates   103704..104132 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes M1 GAS     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 98704..109132
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPY_RS00610 (SPy0100) - 101035..101400 (+) 366 WP_002986560.1 DUF1033 family protein -
  SPY_RS00615 (SPy0101) comGA 101493..102431 (+) 939 WP_010921798.1 competence type IV pilus ATPase ComGA Machinery gene
  SPY_RS00620 (SPy0102) comGB 102367..103401 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPY_RS00625 (SPy0103) comGC 103403..103729 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  SPY_RS00630 (SPy0104) comGD 103704..104132 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPY_RS00635 (SPy0105) comGE 104089..104373 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPY_RS00640 (SPy0106) comGF 104366..104800 (+) 435 WP_010921800.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPY_RS00645 (SPy0107) comGG 104784..105110 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  SPY_RS00650 (SPy0108) comGH 105208..106161 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  SPY_RS00655 (SPy0109) - 106220..107416 (+) 1197 WP_010921803.1 acetate kinase -
  SPY_RS00660 (SPy0110) - 107603..107911 (+) 309 WP_010921804.1 hypothetical protein -
  SPY_RS00665 (SPy0112) proC 107994..108764 (-) 771 WP_010921805.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=21510 SPY_RS00630 WP_002986548.1 103704..104132(+) (comGD) [Streptococcus pyogenes M1 GAS]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=21510 SPY_RS00630 WP_002986548.1 103704..104132(+) (comGD) [Streptococcus pyogenes M1 GAS]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment