Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   SP_RS10335 Genome accession   NC_003028
Coordinates   1949121..1950074 (-) Length   317 a.a.
NCBI ID   WP_000345135.1    Uniprot ID   A0A2U3RW99
Organism   Streptococcus pneumoniae TIGR4     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1944121..1955074
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP_RS10310 (SP_2039) - 1944882..1945505 (-) 624 WP_000932644.1 hypothetical protein -
  SP_RS10315 (SP_2040) jag 1945556..1946542 (-) 987 WP_000260012.1 RNA-binding cell elongation regulator Jag/EloR -
  SP_RS10320 (SP_2041) - 1946561..1947385 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  SP_RS10325 (SP_2042) rnpA 1947360..1947731 (-) 372 WP_000739253.1 ribonuclease P protein component -
  SP_RS13700 (SP_2043) - 1947748..1947879 (-) 132 WP_000768904.1 hypothetical protein -
  SP_RS10330 (SP_2044) - 1947880..1949070 (-) 1191 WP_000167757.1 acetate kinase -
  SP_RS10335 (SP_2045) comYH 1949121..1950074 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  SP_RS12490 (SP_2046) - 1950135..1950729 (-) 595 Protein_1942 class I SAM-dependent methyltransferase -
  SP_RS10350 (SP_2047) comGG/cglG 1950866..1951279 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  SP_RS10355 (SP_2048) comGF/cglF 1951257..1951718 (-) 462 WP_000250534.1 competence type IV pilus minor pilin ComGF Machinery gene
  SP_RS10360 (SP_2049) comGE/cglE 1951681..1951983 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  SP_RS10365 (SP_2050) comGD/cglD 1951946..1952350 (-) 405 WP_000588028.1 competence type IV pilus minor pilin ComGD Machinery gene
  SP_RS10370 (SP_2051) comGC/cglC 1952343..1952669 (-) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  SP_RS10375 (SP_2052) comGB/cglB 1952671..1953687 (-) 1017 WP_074196785.1 competence type IV pilus assembly protein ComGB Machinery gene
  SP_RS10380 (SP_2053) comGA/cglA/cilD 1953635..1954576 (-) 942 WP_000249564.1 competence type IV pilus ATPase ComGA Machinery gene
  SP_RS10385 (SP_2054) - 1954652..1955017 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35756.99 Da        Isoelectric Point: 4.2748

>NTDB_id=21492 SP_RS10335 WP_000345135.1 1949121..1950074(-) (comYH) [Streptococcus pneumoniae TIGR4]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=21492 SP_RS10335 WP_000345135.1 1949121..1950074(-) (comYH) [Streptococcus pneumoniae TIGR4]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAGGAGAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTATTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2U3RW99

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment