Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   BWQ98_RS10805 Genome accession   NZ_CP019299
Coordinates   2004757..2005419 (-) Length   220 a.a.
NCBI ID   WP_000649964.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain HKU1-14     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1999757..2010419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWQ98_RS10780 (BWQ98_10805) - 1999907..2000173 (-) 267 WP_001278167.1 Veg family protein -
  BWQ98_RS10785 (BWQ98_10810) dnaB 2000175..2001527 (-) 1353 WP_050114789.1 replicative DNA helicase -
  BWQ98_RS10790 (BWQ98_10815) rplI 2001571..2002023 (-) 453 WP_050114792.1 50S ribosomal protein L9 -
  BWQ98_RS10795 (BWQ98_10820) - 2002020..2003993 (-) 1974 WP_050205401.1 DHH family phosphoesterase -
  BWQ98_RS10800 (BWQ98_10825) raiA 2004129..2004677 (-) 549 WP_000599107.1 ribosome-associated translation inhibitor RaiA -
  BWQ98_RS10805 (BWQ98_10830) comFC/cflB 2004757..2005419 (-) 663 WP_000649964.1 ComF family protein Machinery gene
  BWQ98_RS10810 (BWQ98_10835) comFA/cflA 2005416..2006714 (-) 1299 WP_050233596.1 DEAD/DEAH box helicase Machinery gene
  BWQ98_RS10815 (BWQ98_10840) - 2006770..2007405 (+) 636 WP_000395730.1 YigZ family protein -
  BWQ98_RS10820 (BWQ98_10845) cysK 2007690..2008610 (+) 921 WP_000029866.1 cysteine synthase A -
  BWQ98_RS10830 (BWQ98_10855) - 2008849..2009214 (-) 366 Protein_2008 IS66 family transposase -
  BWQ98_RS10835 (BWQ98_10860) - 2009196..2009504 (+) 309 Protein_2009 transposase -
  BWQ98_RS10840 (BWQ98_10865) tnpB 2009659..2009982 (-) 324 WP_000586641.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25253.15 Da        Isoelectric Point: 7.3688

>NTDB_id=214733 BWQ98_RS10805 WP_000649964.1 2004757..2005419(-) (comFC/cflB) [Streptococcus pneumoniae strain HKU1-14]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=214733 BWQ98_RS10805 WP_000649964.1 2004757..2005419(-) (comFC/cflB) [Streptococcus pneumoniae strain HKU1-14]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAATAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment