Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   BWQ98_RS08525 Genome accession   NZ_CP019299
Coordinates   1600637..1601296 (+) Length   219 a.a.
NCBI ID   WP_000565010.1    Uniprot ID   A0A0B7M2C6
Organism   Streptococcus pneumoniae strain HKU1-14     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1595637..1606296
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BWQ98_RS08500 (BWQ98_08515) - 1595942..1596259 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  BWQ98_RS08505 (BWQ98_08520) - 1596274..1597170 (-) 897 WP_000825669.1 PEP phosphonomutase -
  BWQ98_RS08510 (BWQ98_08525) - 1597173..1598435 (-) 1263 WP_127245081.1 PTS sugar transporter subunit IIC -
  BWQ98_RS08515 (BWQ98_08530) - 1598715..1599893 (+) 1179 WP_001866460.1 ROK family transcriptional regulator -
  BWQ98_RS08520 (BWQ98_08535) - 1600169..1600567 (-) 399 WP_127245082.1 GNAT family N-acetyltransferase -
  BWQ98_RS08525 (BWQ98_08540) cclA/cilC 1600637..1601296 (+) 660 WP_000565010.1 A24 family peptidase Machinery gene
  BWQ98_RS08530 (BWQ98_08545) - 1601348..1602499 (-) 1152 WP_000481756.1 XRE family transcriptional regulator -
  BWQ98_RS08535 (BWQ98_08550) - 1602514..1603245 (-) 732 Protein_1620 hypothetical protein -
  BWQ98_RS11300 (BWQ98_08555) - 1603474..1603575 (+) 102 Protein_1621 prepilin peptidase -
  BWQ98_RS08545 (BWQ98_08560) trpA 1603547..1604323 (-) 777 WP_001127010.1 tryptophan synthase subunit alpha -
  BWQ98_RS08550 (BWQ98_08565) trpB 1604316..1605539 (-) 1224 WP_000331288.1 tryptophan synthase subunit beta -
  BWQ98_RS08555 (BWQ98_08570) - 1605517..1606116 (-) 600 WP_050233567.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24845.99 Da        Isoelectric Point: 7.5762

>NTDB_id=214702 BWQ98_RS08525 WP_000565010.1 1600637..1601296(+) (cclA/cilC) [Streptococcus pneumoniae strain HKU1-14]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLSQVILITAGLTLGIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLAACVIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=214702 BWQ98_RS08525 WP_000565010.1 1600637..1601296(+) (cclA/cilC) [Streptococcus pneumoniae strain HKU1-14]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTACTTTCCTTGAGTCAAGTCATCCTAATCACTGCTGGTTTGACCTTGGGTAT
CTACGACTTTCGCCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGCGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTGCTTGTGTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0B7M2C6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

100

100

1
  cclA/cilC Streptococcus pneumoniae D39

100

100

1
  cclA/cilC Streptococcus pneumoniae R6

100

100

1
  cclA/cilC Streptococcus pneumoniae TIGR4

94.977

100

0.95
  cclA/cilC Streptococcus mitis SK321

92.694

100

0.927
  cclA/cilC Streptococcus mitis NCTC 12261

87.671

100

0.877

Multiple sequence alignment