Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   BUM80_RS06370 Genome accession   NZ_CP018838
Coordinates   1184521..1185180 (+) Length   219 a.a.
NCBI ID   WP_000564991.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 11A     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1179521..1190180
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BUM80_RS06345 (BUM80_06540) - 1179826..1180143 (-) 318 WP_001151646.1 PTS sugar transporter subunit IIB -
  BUM80_RS06350 (BUM80_06545) - 1180158..1181054 (-) 897 WP_000825665.1 PEP phosphonomutase -
  BUM80_RS06355 (BUM80_06550) - 1181051..1182319 (-) 1269 WP_100910909.1 PTS sugar transporter subunit IIC -
  BUM80_RS06360 (BUM80_06555) - 1182599..1183777 (+) 1179 WP_000175879.1 ROK family transcriptional regulator -
  BUM80_RS06365 (BUM80_06560) - 1184005..1184451 (-) 447 WP_000155412.1 GNAT family N-acetyltransferase -
  BUM80_RS06370 (BUM80_06565) cclA/cilC 1184521..1185180 (+) 660 WP_000564991.1 A24 family peptidase Machinery gene
  BUM80_RS06375 (BUM80_06570) - 1185232..1186383 (-) 1152 WP_000481750.1 ImmA/IrrE family metallo-endopeptidase -
  BUM80_RS06380 (BUM80_06575) - 1186398..1187129 (-) 732 WP_000934018.1 hypothetical protein -
  BUM80_RS06385 (BUM80_06580) - 1187355..1187459 (+) 105 Protein_1211 prepilin peptidase -
  BUM80_RS06390 (BUM80_06585) trpA 1187431..1188207 (-) 777 WP_001127044.1 tryptophan synthase subunit alpha -
  BUM80_RS06395 (BUM80_06590) trpB 1188200..1189423 (-) 1224 WP_000331294.1 tryptophan synthase subunit beta -
  BUM80_RS06400 (BUM80_06595) - 1189401..1190000 (-) 600 WP_000169912.1 phosphoribosylanthranilate isomerase -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24880.03 Da        Isoelectric Point: 7.9671

>NTDB_id=210825 BUM80_RS06370 WP_000564991.1 1184521..1185180(+) (cclA/cilC) [Streptococcus pneumoniae strain 11A]
MIDFYFFLVGSILASFLGLVIDRFPEKSIISSASHCDSCQTRLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELVLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFILQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=210825 BUM80_RS06370 WP_000564991.1 1184521..1185180(+) (cclA/cilC) [Streptococcus pneumoniae strain 11A]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGAA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAGTCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAATTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTTGCTCTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGCGCAGGAGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTTGCTTCTGCGACGGGTATCCT
GGCCTTTATCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae TIGR4

96.347

100

0.963
  cclA/cilC Streptococcus pneumoniae Rx1

95.434

100

0.954
  cclA/cilC Streptococcus pneumoniae D39

95.434

100

0.954
  cclA/cilC Streptococcus pneumoniae R6

95.434

100

0.954
  cclA/cilC Streptococcus mitis SK321

91.781

100

0.918
  cclA/cilC Streptococcus mitis NCTC 12261

85.388

100

0.854

Multiple sequence alignment