Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   BTV19_RS07960 Genome accession   NZ_CP018803
Coordinates   1725933..1727039 (-) Length   368 a.a.
NCBI ID   WP_075294326.1    Uniprot ID   -
Organism   Histophilus somni strain USDA-ARS-USMARC-63255     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1690326..1728952 1725933..1727039 within 0


Gene organization within MGE regions


Location: 1690326..1728952
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BTV19_RS07790 (BTV19_07780) - 1690326..1691462 (-) 1137 WP_075319828.1 RNA-guided endonuclease InsQ/TnpB family protein -
  BTV19_RS07795 (BTV19_07785) tnpA 1691560..1691787 (+) 228 Protein_1516 IS200/IS605 family transposase -
  BTV19_RS07800 (BTV19_07790) htpG 1691964..1693844 (-) 1881 WP_075294303.1 molecular chaperone HtpG -
  BTV19_RS07805 (BTV19_07795) - 1694141..1697050 (-) 2910 WP_075294304.1 lactoferrin/transferrin family TonB-dependent receptor -
  BTV19_RS07810 (BTV19_07800) - 1697255..1699075 (-) 1821 WP_307777290.1 transferrin-binding protein-like solute binding protein -
  BTV19_RS07815 (BTV19_07805) relB 1699611..1699832 (+) 222 WP_075294306.1 type II toxin-antitoxin system RelB family antitoxin -
  BTV19_RS07820 (BTV19_07810) - 1699832..1700092 (+) 261 WP_075294307.1 type II toxin-antitoxin system RelE family toxin -
  BTV19_RS07830 (BTV19_07820) - 1700270..1701721 (-) 1452 WP_075294308.1 surface lipoprotein assembly modifier -
  BTV19_RS07835 (BTV19_07825) - 1701837..1702028 (-) 192 WP_075294309.1 hypothetical protein -
  BTV19_RS07840 (BTV19_07830) - 1702207..1702620 (-) 414 Protein_1524 pseudouridine synthase -
  BTV19_RS07845 (BTV19_07835) - 1702692..1704032 (-) 1341 WP_075294311.1 PTS sugar transporter subunit IIC -
  BTV19_RS07850 (BTV19_07840) - 1704035..1705369 (-) 1335 WP_075319830.1 alpha-L-fucosidase -
  BTV19_RS10495 - 1705760..1705941 (+) 182 Protein_1527 IS1595 family transposase -
  BTV19_RS07860 - 1706468..1707028 (-) 561 WP_081376599.1 hypothetical protein -
  BTV19_RS07865 (BTV19_07855) - 1707043..1707951 (-) 909 WP_075294313.1 Kiwa anti-phage protein KwaB-like domain-containing protein -
  BTV19_RS07870 (BTV19_07860) - 1708001..1708408 (-) 408 WP_232451443.1 very short patch repair endonuclease -
  BTV19_RS07875 (BTV19_07865) - 1708444..1709529 (-) 1086 WP_075294315.1 HpaII family restriction endonuclease -
  BTV19_RS07880 (BTV19_07870) - 1709535..1710575 (-) 1041 WP_075294316.1 DNA cytosine methyltransferase -
  BTV19_RS07885 (BTV19_07875) - 1710568..1710783 (-) 216 WP_008752997.1 helix-turn-helix domain-containing protein -
  BTV19_RS07890 (BTV19_07880) - 1710864..1711460 (-) 597 WP_198351454.1 Arm DNA-binding domain-containing protein -
  BTV19_RS07895 (BTV19_07885) - 1711472..1711663 (-) 192 WP_075294317.1 hypothetical protein -
  BTV19_RS07900 (BTV19_07890) - 1711825..1712427 (+) 603 WP_075294318.1 helix-turn-helix domain-containing protein -
  BTV19_RS07905 (BTV19_07895) - 1712480..1713148 (+) 669 WP_075294319.1 hypothetical protein -
  BTV19_RS07910 (BTV19_07900) guaA 1713335..1714906 (-) 1572 WP_075294320.1 glutamine-hydrolyzing GMP synthase -
  BTV19_RS07915 (BTV19_07905) - 1714928..1715236 (-) 309 WP_041605033.1 hypothetical protein -
  BTV19_RS07920 (BTV19_07910) guaB 1715307..1716770 (-) 1464 WP_075294321.1 IMP dehydrogenase -
  BTV19_RS07925 (BTV19_07915) birA 1716937..1717869 (+) 933 WP_075294322.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
  BTV19_RS07930 (BTV19_07920) glnA 1718093..1719511 (-) 1419 WP_075294323.1 type I glutamate--ammonia ligase -
  BTV19_RS07935 (BTV19_07925) typA 1719754..1721604 (+) 1851 WP_012341568.1 translational GTPase TypA -
  BTV19_RS07940 (BTV19_07930) rpsT 1721666..1721929 (-) 264 WP_011608572.1 30S ribosomal protein S20 -
  BTV19_RS07945 (BTV19_07935) murJ 1722207..1723778 (+) 1572 WP_075294324.1 murein biosynthesis integral membrane protein MurJ -
  BTV19_RS07950 (BTV19_07940) ftsY 1723941..1725284 (-) 1344 WP_075294325.1 signal recognition particle-docking protein FtsY -
  BTV19_RS07955 (BTV19_07945) rsmD 1725348..1725950 (+) 603 WP_011608569.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  BTV19_RS07960 (BTV19_07950) dprA 1725933..1727039 (-) 1107 WP_075294326.1 DNA-processing protein DprA Machinery gene
  BTV19_RS07965 (BTV19_07955) tsaD 1727275..1728303 (+) 1029 WP_011608567.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD -
  BTV19_RS07970 (BTV19_07960) - 1728365..1728952 (+) 588 WP_011608566.1 thymidine kinase -

Sequence

Protein


Download         Length: 368 a.a.        Molecular weight: 41519.72 Da        Isoelectric Point: 6.5011

>NTDB_id=210382 BTV19_RS07960 WP_075294326.1 1725933..1727039(-) (dprA) [Histophilus somni strain USDA-ARS-USMARC-63255]
MDKRNELLLRLLQVPKLGASGITQLLSHIDLKTLEDYDDVAFHYLGWKPEQINRWLYPDLRYIEPALFWASKKGHYLMNF
YQENYPYLLKQTIGAPPLLFIKGNPEILAQQQVAIVGSRHCSHYGEYWAKYFATELFLAGFVITSGLALGIDGFCHQAVV
DIQGQTIGVLGGGLEELYPKQHKKLAQQMLDYGGALVSEFLPHQPPKPQHFPQRNRIISGLSKGVLVVEATEKSGSLITA
RYALEQNREVFALPGQIQNEYSQGCHRLIKDGALLVENVADIVENLSPFTHYERQLTAKQIETQFPPAYKLPASPTYPEL
YAHIGYTPVGLDELSNKSGLSVDTLLIQLLELELQDLVIAEKGLYRRT

Nucleotide


Download         Length: 1107 bp        

>NTDB_id=210382 BTV19_RS07960 WP_075294326.1 1725933..1727039(-) (dprA) [Histophilus somni strain USDA-ARS-USMARC-63255]
ATGGATAAACGGAATGAGCTGTTACTGCGTTTGTTACAAGTGCCGAAGTTGGGAGCGTCCGGAATAACTCAACTTTTATC
ACACATCGATTTAAAAACATTAGAGGATTATGATGATGTTGCGTTTCATTATTTAGGCTGGAAACCTGAACAGATAAATA
GATGGTTGTATCCGGATCTTAGATATATTGAACCTGCATTATTTTGGGCAAGCAAAAAGGGACATTATTTGATGAATTTC
TATCAAGAGAATTACCCTTATTTATTAAAGCAAACCATAGGTGCTCCCCCTTTGTTATTTATCAAAGGCAATCCGGAAAT
ACTTGCTCAACAACAAGTCGCTATTGTAGGAAGCCGTCATTGCTCACATTATGGCGAGTATTGGGCAAAGTATTTTGCAA
CGGAATTGTTCCTTGCCGGTTTTGTTATTACCAGTGGACTGGCTCTAGGGATAGACGGTTTTTGTCATCAGGCTGTTGTG
GATATTCAAGGACAAACTATCGGGGTATTAGGGGGAGGTTTGGAAGAGTTGTATCCCAAACAACATAAAAAATTAGCACA
ACAAATGCTAGATTATGGCGGTGCGTTAGTGTCAGAATTTTTACCTCATCAGCCTCCCAAACCACAACATTTTCCTCAAC
GTAATCGCATTATTAGCGGACTTTCTAAAGGTGTTTTAGTGGTTGAGGCAACAGAAAAAAGCGGTTCACTCATTACTGCA
CGTTATGCTTTAGAACAAAATAGAGAAGTTTTTGCACTTCCAGGACAAATTCAAAATGAGTATAGTCAAGGGTGTCATAG
ATTAATAAAAGACGGTGCGTTGTTAGTAGAGAATGTTGCAGATATTGTAGAAAATTTATCGCCTTTTACGCATTATGAAC
GTCAACTAACAGCAAAACAGATAGAAACGCAATTTCCGCCGGCTTATAAGTTACCTGCTTCACCGACTTATCCTGAACTC
TATGCCCATATTGGTTATACGCCGGTAGGGCTTGATGAATTATCAAATAAAAGCGGATTAAGTGTAGATACCTTATTGAT
ACAGCTGTTAGAACTTGAATTGCAAGATCTCGTTATTGCTGAAAAAGGGTTATATCGACGGACTTAA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(310-361)

DNA recombination-mediator protein A (DNA_processg_A)

(71-277)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Haemophilus influenzae Rd KW20

61.126

100

0.62
  dprA Glaesserella parasuis strain SC1401

50.432

94.293

0.476
  dprA Vibrio cholerae strain A1552

44.986

100

0.451
  dprA Vibrio campbellii strain DS40M4

41.096

99.185

0.408
  dprA Legionella pneumophila strain ERS1305867

38.798

99.457

0.386

Multiple sequence alignment