Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   BTV18_RS06185 Genome accession   NZ_CP018802
Coordinates   1348024..1349157 (+) Length   377 a.a.
NCBI ID   WP_012340255.1    Uniprot ID   A0A9Q6YYH7
Organism   Histophilus somni strain USDA-ARS-USMARC-63250     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1343024..1354157
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BTV18_RS06165 (BTV18_06125) - 1343514..1346054 (-) 2541 WP_075293729.1 penicillin-binding protein 1A -
  BTV18_RS06170 (BTV18_06130) - 1346179..1346964 (+) 786 WP_012340257.1 hypothetical protein -
  BTV18_RS06175 (BTV18_06135) - 1346968..1347507 (+) 540 WP_012340256.1 PilN domain-containing protein -
  BTV18_RS06180 (BTV18_06140) - 1347511..1348008 (+) 498 WP_011609266.1 hypothetical protein -
  BTV18_RS06185 (BTV18_06145) comE 1348024..1349157 (+) 1134 WP_012340255.1 type IV pilus secretin PilQ Machinery gene
  BTV18_RS06190 (BTV18_06150) aroK 1349339..1349866 (+) 528 WP_012340254.1 shikimate kinase AroK -
  BTV18_RS06195 (BTV18_06155) aroB 1349886..1350974 (+) 1089 WP_075293728.1 3-dehydroquinate synthase -
  BTV18_RS06200 (BTV18_06160) - 1350981..1351844 (+) 864 WP_075293727.1 Dam family site-specific DNA-(adenine-N6)-methyltransferase -
  BTV18_RS06205 (BTV18_06165) galU 1351892..1352779 (-) 888 WP_075293726.1 UTP--glucose-1-phosphate uridylyltransferase GalU -

Sequence

Protein


Download         Length: 377 a.a.        Molecular weight: 42360.38 Da        Isoelectric Point: 6.4072

>NTDB_id=210353 BTV18_RS06185 WP_012340255.1 1348024..1349157(+) (comE) [Histophilus somni strain USDA-ARS-USMARC-63250]
MLIKNFLYFFLFLFTVSVELSARDPFDKRQRSIKKETNIQLDTKENLSKSTNEPNLTTTSIKLHYAKAADVMKSLTTGQG
SWLSSNGTFSFDERSNLLLIQDNQETLNALKKLIKEMDQPIEQIAIEARIVTISDENLKELGVRWGIFEPTNNAHHLSGN
LAANGFQHLTEQLNVNFATTATPAGSIALQIAKINDRLLDLELTALERENNVEIIASPRLLTTNKQSASIKQGTEIPYVI
TGKKSDEQKVEFREAVLGLEVTPHISKDNTILLDLIVSQNSPGSRITYGQNEMVSIDKQEINTQVFAQDGETIVLGGVFH
DTITKGVDKVPLLGDIPILKRLFSRESERHQKRELVIFVTPRIIRSEQPNEIIKPLK

Nucleotide


Download         Length: 1134 bp        

>NTDB_id=210353 BTV18_RS06185 WP_012340255.1 1348024..1349157(+) (comE) [Histophilus somni strain USDA-ARS-USMARC-63250]
ATGTTAATTAAAAATTTCTTATATTTCTTTTTGTTCTTATTCACAGTAAGTGTGGAATTATCTGCTAGAGATCCCTTTGA
TAAAAGACAAAGAAGCATAAAAAAAGAGACAAATATACAATTAGATACAAAGGAAAATTTGTCAAAATCGACTAATGAGC
CAAATTTAACGACGACTTCGATCAAATTACATTATGCTAAAGCGGCTGATGTAATGAAATCACTGACTACAGGTCAAGGT
TCATGGCTTTCATCAAATGGAACTTTTAGTTTTGATGAACGAAGTAACTTGCTCTTAATTCAGGATAATCAGGAAACTCT
CAATGCCTTAAAAAAATTAATCAAAGAAATGGATCAACCTATTGAACAAATTGCAATTGAAGCGAGAATTGTAACAATTA
GCGATGAAAATTTAAAAGAATTGGGGGTTCGTTGGGGAATTTTTGAGCCTACAAATAACGCTCATCATCTTTCAGGCAAT
CTAGCAGCAAACGGATTTCAGCATTTAACGGAACAACTTAACGTCAATTTTGCTACTACCGCAACACCTGCAGGTTCTAT
TGCTTTACAAATTGCCAAAATTAATGATCGACTTTTAGACTTAGAACTTACCGCACTTGAACGAGAAAATAATGTAGAAA
TTATTGCAAGCCCTCGTTTACTTACAACGAATAAGCAAAGTGCAAGTATTAAACAAGGAACTGAAATTCCTTATGTTATT
ACCGGCAAGAAATCTGATGAACAGAAAGTAGAGTTTAGAGAAGCAGTTTTAGGATTAGAAGTAACGCCACACATTTCTAA
AGACAATACTATTTTACTGGATCTCATTGTAAGCCAAAACTCCCCTGGAAGTCGTATTACTTATGGGCAAAATGAAATGG
TATCTATTGATAAACAAGAAATTAATACTCAAGTTTTTGCACAAGATGGGGAAACGATTGTGTTGGGTGGCGTATTTCAC
GATACAATCACAAAAGGAGTAGATAAAGTACCGCTGTTAGGAGACATACCTATATTAAAAAGACTGTTCAGCCGTGAAAG
TGAAAGACACCAAAAACGTGAATTAGTCATTTTTGTTACCCCAAGGATCATTCGTTCAGAACAACCTAATGAAATAATAA
AACCATTAAAATAG

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(60-123)

Bacterial type II and III secretion system protein (Secretin)

(205-365)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

74.769

86.207

0.645
  comE Haemophilus influenzae Rd KW20

74.462

86.207

0.642
  comE Glaesserella parasuis strain SC1401

61.587

83.554

0.515
  pilQ Vibrio campbellii strain DS40M4

44.932

96.817

0.435
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

47.205

85.411

0.403
  pilQ Vibrio cholerae strain A1552

47.205

85.411

0.403

Multiple sequence alignment