Detailed information NTG0020834

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ECs_4151
• Genome accession: NC_002695
• Coordinates: 4167576..4168700 (-)
• Length: 374 a.a.
• NCBI ID: NP_312178.1
• Uniprot ID: -
• Organism: Escherichia coli O157:H7 str. Sakai
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 4162576..4173700

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ECs_4145	yrdA	4164376..4164930 (+)	555	NP_312172.2	transferase	-
ECs_4146	yrdB	4164906..4165163 (-)	258	NP_312173.1	hypothetical protein	-
ECs_4147	aroE	4165160..4165978 (-)	819	NP_312174.1	dehydroshikimate reductase NAD(P)-binding protein	-
ECs_4148	tsaC	4165983..4166555 (-)	573	NP_312175.1	tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein	-
ECs_4149	yrdD	4166560..4167102 (-)	543	NP_312176.2	ssDNA-binding protein	-
ECs_4150	smg	4167131..4167604 (-)	474	NP_312177.1	hypothetical protein	-
ECs_4151	dprA	4167576..4168700 (-)	1125	NP_312178.1	hypothetical protein	Machinery gene
ECs_4152	def	4168830..4169339 (+)	510	NP_312179.1	peptide deformylase	-
ECs_4153	fmt	4169354..4170301 (+)	948	NP_312180.1	L-methionyl-tRNA(fMet) N-formyltransferase	-
ECs_4154	rsmB	4170347..4171636 (+)	1290	NP_312181.2	16S rRNA m(5)C967 methyltransferase	-
ECs_4155	trkA	4171658..4173034 (+)	1377	NP_312182.1	NAD-binding component of TrK potassium transporter	-
ECs_4156	mscL	4173164..4173574 (+)	411	NP_312183.1	mechanosensitive channel protein	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 41005.96 Da
• Isoelectric Point: 6.2655

>NTDB_id=20834 ECs_4151 NP_312178.1 4167576..4168700(-) (dprA) [Escherichia coli O157:H7 str. Sakai]
MVDTEIWLRLMSISSLYGDDMVRIAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSE
FYPPQLLATTDYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVN
GVSIAVLGNGLNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCA
LEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDE
VTPVDVVAERAGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide

• Length: 1125 bp

>NTDB_id=20834 ECs_4151 NP_312178.1 4167576..4168700(-) (dprA) [Escherichia coli O157:H7 str. Sakai]
ATGGTCGATACAGAAATTTGGCTGCGTTTAATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTATAGCTCACTG
GCTGGCAAGACAGTCGCATATTGATGCGGTTGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTT
CATTTCCGCGGAAGAGTATCGAAAGCTCACTTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAA
TTTTATCCTCCTCAACTTCTGGCGACGACAGATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTC
ATTTCAGCTTGCCGTAGTGGGGAGTCGGGCGCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGG
CGAAGCATGGAGTGACAATTACGAGTGGACTGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAAT
GGCGTCAGCATTGCTGTATTGGGGAATGGACTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCT
TGAACAGGGGGGCGCTCTCGTCTCGGAATTTCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCA
TTATCAGTGGTCTAAGTAAAGGTGTACTGGTGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCG
CTTGAGCAGGGGCGAGAAGTTTTTGCCTTGCCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAA
ACAAGGTGCGATTCTTGTGACGGAACCGGAAGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCC
CTGAAAATTCATTTTATTCACCAGATCAGGAAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAG
GTAACACCTGTTGACGTCGTCGCTGAACGTGCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTT
AGCAGGATGGATCGCAGCTGTACCCGGCGGCTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTG
TTTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (312-357)

• DNA recombination-mediator protein A (DNA_processg_A) (67-274)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Vibrio campbellii strain DS40M4	48.78	98.663	0.481
dprA	Glaesserella parasuis strain SC1401	45.401	90.107	0.409
dprA	Vibrio cholerae strain A1552	49.355	82.888	0.409
dprA	Haemophilus influenzae Rd KW20	44.214	90.107	0.398
dprA	Legionella pneumophila strain ERS1305867	44.545	88.235	0.393