Detailed information NTG0208237

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: BSL41_RS08560
• Genome accession: NZ_CP018347
• Coordinates: 1560007..1560960 (-)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae strain SWU02
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1555007..1565960

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BSL41_RS11960	-	1555488..1555583 (-)	96	Protein_1532	IS630 family transposase	-
BSL41_RS08540	-	1555996..1556337 (+)	342	Protein_1533	transposase	-
BSL41_RS08545	prsA	1556454..1557395 (-)	942	WP_000727935.1	peptidylprolyl isomerase PrsA	-
BSL41_RS08550	-	1557462..1558175 (-)	714	WP_000230400.1	O-methyltransferase	-
BSL41_RS08555	pepF	1558177..1559988 (-)	1812	WP_000244158.1	oligoendopeptidase F	Regulator
BSL41_RS08560	coiA	1560007..1560960 (-)	954	WP_000495909.1	competence protein CoiA	Machinery gene
BSL41_RS08565	tehB	1561033..1561893 (-)	861	WP_000413757.1	SAM-dependent methyltransferase TehB	-
BSL41_RS08570	smpB	1561909..1562376 (-)	468	WP_001051750.1	SsrA-binding protein SmpB	-
BSL41_RS08575	rnr	1562339..1564693 (-)	2355	WP_000654886.1	ribonuclease R	-
BSL41_RS08580	secG	1564795..1565028 (-)	234	WP_000282517.1	preprotein translocase subunit SecG	-
BSL41_RS08585	rpmG	1565068..1565217 (-)	150	WP_001810029.1	50S ribosomal protein L33	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=208237 BSL41_RS08560 WP_000495909.1 1560007..1560960(-) (coiA) [Streptococcus pneumoniae strain SWU02]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=208237 BSL41_RS08560 WP_000495909.1 1560007..1560960(-) (coiA) [Streptococcus pneumoniae strain SWU02]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTAAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435