Detailed information NTG0207804

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: CO687_RS03515
• Genome accession: NZ_CP023511
• Coordinates: 711089..713632 (+)
• Length: 847 a.a.
• NCBI ID: WP_096754946.1
• Uniprot ID: -
• Organism: Streptococcus gordonii strain FDAARGOS_371
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 706089..718632

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO687_RS03500 (CO687_03500)	-	707491..708426 (+)	936	WP_045504665.1	YitT family protein	-
CO687_RS03505 (CO687_03505)	argS	708656..710344 (-)	1689	WP_061596046.1	arginine--tRNA ligase	-
CO687_RS03510 (CO687_03510)	argR	710473..710910 (+)	438	WP_045504660.1	arginine repressor	-
CO687_RS03515 (CO687_03515)	hexA	711089..713632 (+)	2544	WP_096754946.1	DNA mismatch repair protein MutS	Machinery gene
CO687_RS03520 (CO687_03520)	-	713681..714151 (-)	471	WP_008809981.1	DUF3021 family protein	-
CO687_RS03525 (CO687_03525)	brsR	714148..714588 (-)	441	WP_008809980.1	LytTR family DNA-binding domain-containing protein	Regulator
CO687_RS03530 (CO687_03530)	hexB	714773..716716 (+)	1944	WP_096754947.1	DNA mismatch repair endonuclease MutL	Machinery gene
CO687_RS03535 (CO687_03535)	-	716752..717273 (-)	522	WP_061596048.1	RDD family protein	-
CO687_RS03540 (CO687_03540)	-	717257..717763 (-)	507	WP_045634808.1	helix-turn-helix transcriptional regulator	-
CO687_RS03545 (CO687_03545)	ruvA	717931..718524 (+)	594	WP_045634768.1	Holliday junction branch migration protein RuvA	Machinery gene

Sequence

Protein

• Length: 847 a.a.
• Molecular weight: 95147.37 Da
• Isoelectric Point: 4.7973

>NTDB_id=207804 CO687_RS03515 WP_096754946.1 711089..713632(+) (hexA) [Streptococcus gordonii strain FDAARGOS_371]
MATEKISPGMQQYLDIKKDYQDAFLLFRMGDFYELFYEDAVNAAQILEIALTSRNKNSENPIPMAGVPYHSAQQYIDVLI
ESGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPAGENNFLVALDRQEQAYGLAYMDLATGEFQVTSLADFDQ
ACGEIRNLRAREVVVGYCLSEDEQQVLSKQMNLLLSEVEEAMEDVQLLGDELSSLEKQTAGKLLAYVFQTQMRELSHLKK
AHHYEIKDFLQMDYATKTSLDLTENARTGKKHGSLFWLMDETKTAMGGRLLRSWIQHPLIDKGRIIKRQDVVQVFLDYFF
ERSDLADSLKGVYDIERLVSRVSFGKTNPKDLLQLSSTLSHVPQIRAILETIESPALESLVARLDAIPELENLISSAIDP
DAPQVITEGNIIRTGFDETLDQYRLVMREGTSWIADIEAKEREASGIANLKIDYNKKDGYYFHVTNSQLSNVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEVGKYIQRLQALAQTLATVDVLQSFAVVAESQHLVRPSFT
SSRSLQIKKGRHAVVEKVMGAQSYIPNSIELGQETDIQLITGPNMSGKSTYMRQLAMIVIMAQMGSYVPAEVASLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANRAIRQASERSLILFDELGRGTATYDGMALAQAIIEYIHDRTKAKTLFATHYHEL
TDLSSSLTRLENVHVATLEKDGQVTFLHKIEAGPADKSYGIHVAKIAGLPKDLLTRADEILTDLENQEKREASLPASRTD
SQKVSEQMSLFVEETENPVLTELRDLDIYNMTPLEVMAAVAELKKKL

Nucleotide

• Length: 2544 bp

>NTDB_id=207804 CO687_RS03515 WP_096754946.1 711089..713632(+) (hexA) [Streptococcus gordonii strain FDAARGOS_371]
ATGGCAACAGAAAAAATATCGCCAGGTATGCAGCAGTACTTGGATATTAAAAAAGACTATCAGGACGCCTTCCTGTTGTT
TCGTATGGGTGATTTCTATGAATTGTTTTACGAGGATGCTGTTAATGCGGCACAGATTCTCGAGATTGCCCTGACTAGCC
GTAATAAGAATTCAGAAAATCCCATTCCAATGGCGGGTGTACCTTATCACTCTGCCCAGCAATATATTGATGTTTTGATT
GAGTCTGGTTATAAGGTTGCCATTGCAGAGCAGATGGAAGATCCTAAACAGGCCGTGGGGGTGGTCAAACGCGAGGTGGT
CCAGGTTATTACGCCGGGTACGGTAGTGGATTCTAGTAAGCCAGCCGGAGAAAATAACTTTTTGGTTGCTTTGGATAGGC
AGGAGCAAGCTTATGGCTTGGCTTATATGGATCTGGCTACGGGAGAATTTCAGGTGACCAGCCTGGCAGATTTTGACCAA
GCTTGTGGAGAAATTCGAAATCTCCGGGCTCGGGAAGTGGTCGTGGGTTATTGCTTGTCAGAAGATGAGCAGCAGGTTTT
GTCAAAACAAATGAATTTACTCCTGTCAGAAGTCGAGGAAGCAATGGAGGACGTTCAGCTCTTAGGAGATGAGTTGTCAT
CTTTAGAAAAGCAGACGGCAGGGAAGCTTTTGGCCTATGTTTTTCAGACGCAGATGCGGGAGCTCAGCCATCTCAAAAAG
GCCCATCATTATGAGATAAAAGATTTTCTTCAGATGGACTATGCTACAAAGACCAGTCTGGACTTGACTGAAAATGCCCG
GACGGGCAAGAAGCATGGTAGTCTTTTTTGGCTCATGGATGAAACAAAAACAGCCATGGGAGGACGCTTGCTTCGTTCTT
GGATCCAGCATCCCTTGATTGATAAGGGACGAATTATCAAGCGTCAAGATGTCGTTCAGGTCTTTCTGGATTATTTCTTT
GAGCGGAGTGATTTGGCAGATAGTCTCAAGGGCGTCTATGATATTGAACGCCTGGTAAGTCGTGTGTCATTTGGCAAGAC
CAATCCCAAGGACCTCCTGCAATTATCTTCTACTCTGAGCCATGTTCCTCAGATTCGGGCCATTTTAGAAACGATTGAAA
GCCCAGCTCTGGAGAGTTTGGTGGCAAGGCTAGATGCGATTCCTGAACTGGAAAATCTAATCAGCTCTGCGATTGACCCA
GATGCTCCACAAGTAATTACTGAGGGCAATATCATTCGAACTGGTTTTGACGAGACTTTGGACCAGTACCGTTTGGTCAT
GAGAGAGGGGACTAGCTGGATTGCGGACATTGAAGCCAAGGAGCGAGAGGCAAGTGGTATTGCTAATCTGAAAATTGATT
ATAACAAGAAGGATGGTTACTATTTCCATGTAACTAATTCTCAACTAAGCAATGTTCCTAGCCATTTCTTCCGAAAAGCA
ACCTTGAAAAATTCTGAGCGTTTTGGTACGGAAGAGCTGGCGCGCATTGAAGGCGAGATGTTGGAGGCGCGTGAGAAGTC
TGCTAATCTGGAATATGAGATCTTCATGCGCATTCGTGAAGAGGTCGGAAAATATATTCAACGGCTACAAGCCTTAGCTC
AAACCCTAGCTACGGTCGATGTTTTACAGAGCTTTGCGGTTGTGGCTGAAAGTCAACACTTAGTCCGTCCAAGTTTTACA
AGCAGTCGTAGTTTGCAGATTAAAAAAGGCCGTCATGCGGTTGTCGAAAAAGTCATGGGAGCCCAAAGCTACATCCCAAA
TAGTATCGAACTGGGTCAAGAAACAGATATTCAGCTGATTACTGGACCAAATATGAGCGGGAAGTCAACCTACATGCGAC
AGCTGGCAATGATTGTCATCATGGCTCAAATGGGATCGTATGTACCGGCAGAAGTAGCCAGTCTTCCGATTTTCGATGCT
ATCTTTACACGAATAGGTGCGGCGGATGATTTAGTTTCTGGGCAGTCGACCTTTATGGTAGAAATGATGGAGGCTAATCG
GGCCATTCGACAAGCAAGTGAACGCTCTTTGATCCTTTTTGATGAACTGGGACGGGGGACTGCGACTTATGATGGGATGG
CTCTGGCGCAAGCAATTATTGAGTATATTCATGACCGTACCAAGGCCAAGACTCTTTTTGCAACCCATTATCATGAGTTG
ACAGACCTGTCAAGTAGCTTGACACGATTGGAAAACGTCCATGTGGCAACTCTAGAAAAAGATGGCCAAGTGACATTTTT
GCATAAGATTGAAGCAGGACCTGCTGACAAGTCTTACGGGATTCATGTGGCCAAGATTGCTGGATTGCCAAAAGATTTAC
TGACAAGGGCAGATGAGATTTTGACAGATTTGGAAAATCAAGAGAAAAGAGAGGCTTCTCTTCCAGCGTCTAGAACGGAC
TCCCAAAAAGTGTCTGAGCAGATGTCGCTTTTTGTAGAAGAAACGGAAAATCCAGTCCTGACTGAACTCCGAGACTTGGA
CATCTACAATATGACTCCCCTAGAAGTTATGGCAGCAGTGGCTGAGTTGAAGAAGAAGTTGTAA

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	77.804	100	0.778
mutS	Pseudomonas stutzeri strain ATCC 17587	36.86	100	0.374