Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   BFL18_RS22445 Genome accession   NZ_CP018247
Coordinates   4066539..4067633 (-) Length   364 a.a.
NCBI ID   WP_072619049.1    Uniprot ID   -
Organism   Escherichia coli strain 7784     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 4067711..4068924 4066539..4067633 flank 78


Gene organization within MGE regions


Location: 4066539..4068924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFL18_RS22445 (BFL18_22215) dprA 4066539..4067633 (-) 1095 WP_072619049.1 DNA-protecting protein DprA Machinery gene
  BFL18_RS22465 (BFL18_22230) - 4067711..4068924 (+) 1214 WP_162829202.1 IS3-like element IS1203 family transposase -

Sequence

Protein


Download         Length: 364 a.a.        Molecular weight: 39736.40 Da        Isoelectric Point: 6.3835

>NTDB_id=207541 BFL18_RS22445 WP_072619049.1 4066539..4067633(-) (dprA) [Escherichia coli strain 7784]
MSISSLYGDDMVRTAHWLARQSHIDAVVLQQTGLTLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLATT
DYPGALFVEGELHALHSFQLAVVGSRAHSWYGERWGRLFCETLAKHGVTITSGLARGIDGVAHKAALQVNGVSIAVLGNG
LNTIHPRRHARLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGLSKGVLVVEAALRSGSLVTARCALEQGREVFAL
PGPIGNPGSEGPHWLIKQGAILVTEPEEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDEVTPVDVVAER
AGQPVPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV

Nucleotide


Download         Length: 1095 bp        

>NTDB_id=207541 BFL18_RS22445 WP_072619049.1 4066539..4067633(-) (dprA) [Escherichia coli strain 7784]
ATGAGTATCAGCAGCTTGTACGGCGATGATATGGTCCGTACAGCTCACTGGCTGGCAAGACAGTCGCATATTGATGCGGT
TGTATTGCAGCAAACAGGGCTTACATTGCGGCAGGCACAACGCTTTCTTTCATTTCCGCGGAAGAGTATCGAAAGCTCAC
TTTGTTGGTTGGAGCAACCCAACCATCATTTAATCCCTGCGGACAGCGAATTTTATCCTCCTCAACTTCTGGCGACGACA
GATTACCCCGGTGCACTGTTTGTTGAAGGAGAACTGCACGCGCTGCATTCATTTCAGCTTGCCGTAGTGGGGAGTCGGGC
GCATTCATGGTATGGCGAGCGATGGGGACGATTATTTTGCGAAACTCTGGCGAAGCATGGAGTGACAATTACGAGTGGAC
TGGCGCGTGGAATCGATGGTGTAGCGCATAAAGCAGCCTTACAGGTAAATGGCGTCAGCATTGCTGTATTGGGGAATGGA
CTTAATACCATTCATCCCCGCCGTCATGCCCGACTGGCTGCCAGTCTGCTTGAACAGGGGGGCGCTCTCGTCTCGGAATT
TCCCCTCGATGTTCCACCCCTTGCTTACAATTTCCCACGAAGAAATCGCATTATCAGTGGTCTAAGTAAAGGTGTACTGG
TGGTGGAAGCGGCTTTGCGTAGTGGTTCGCTGGTGACAGCACGTTGTGCGCTTGAGCAGGGGCGAGAAGTTTTTGCCTTG
CCAGGTCCAATAGGGAATCCGGGAAGCGAAGGGCCTCACTGGTTAATAAAACAAGGTGCGATTCTTGTGACGGAACCGGA
AGAAATTCTGGAAAACTTGCAATTTGGATTGCACTGGTTGCCAGACGCCCCTGAAAATTCATTTTATTCACCAGATCAGG
AAGACGTGGCATTGCCATTTCCTGAGCTCCTGGCTAACGTAGGAGATGAGGTAACACCTGTTGACGTCGTCGCTGAACGT
GCCGGCCAACCTGTGCCAGAGGTAGTTACTCAACTACTCGAACTGGAGTTAGCAGGATGGATCGCAGCTGTACCCGGCGG
CTATGTCCGATTGAGGAGGGCATGCCATGTTCGACGTACTAATGTATTTGTTTGA

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(302-347)

DNA recombination-mediator protein A (DNA_processg_A)

(57-264)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

48.889

98.901

0.484
  dprA Glaesserella parasuis strain SC1401

45.401

92.582

0.42
  dprA Vibrio cholerae strain A1552

49.355

85.165

0.42
  dprA Legionella pneumophila strain ERS1305867

44.545

90.659

0.404
  dprA Haemophilus influenzae Rd KW20

44.86

88.187

0.396

Multiple sequence alignment