Detailed information NTG0207451

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: CO204_RS07250
• Genome accession: NZ_CP023477
• Coordinates: 1424899..1425837 (-)
• Length: 312 a.a.
• NCBI ID: WP_002261897.1
• Uniprot ID: Q8DV62
• Organism: Streptococcus mutans strain LAR01
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1419899..1430837

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CO204_RS07230 (CO204_07200)	prsA	1420424..1421425 (-)	1002	WP_002261893.1	peptidylprolyl isomerase PrsA	-
CO204_RS07235 (CO204_07205)	-	1421487..1422194 (-)	708	WP_002275166.1	O-methyltransferase	-
CO204_RS07240 (CO204_07210)	-	1422244..1422861 (-)	618	WP_019313144.1	HAD-IA family hydrolase	-
CO204_RS07245 (CO204_07215)	pepF	1423078..1424877 (-)	1800	WP_019313143.1	oligoendopeptidase F	Regulator
CO204_RS07250 (CO204_07220)	coiA	1424899..1425837 (-)	939	WP_002261897.1	competence protein CoiA family protein	Machinery gene
CO204_RS07255 (CO204_07225)	-	1426144..1427037 (-)	894	WP_002267117.1	alpha/beta hydrolase	-
CO204_RS07260 (CO204_07230)	-	1427143..1427424 (-)	282	WP_025988629.1	hypothetical protein	-
CO204_RS10750	-	1427509..1427636 (+)	128	Protein_1363	ArsR/SmtB family transcription factor	-
CO204_RS07270 (CO204_07235)	-	1427668..1428636 (-)	969	WP_002304278.1	alcohol dehydrogenase catalytic domain-containing protein	-
CO204_RS07275 (CO204_07240)	-	1428764..1430137 (+)	1374	WP_002276533.1	PLP-dependent aminotransferase family protein	-
CO204_RS07280 (CO204_07245)	-	1430191..1430691 (-)	501	WP_019313142.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 36721.05 Da
• Isoelectric Point: 8.7637

>NTDB_id=207451 CO204_RS07250 WP_002261897.1 1424899..1425837(-) (coiA) [Streptococcus mutans strain LAR01]
MLVARDKNGKLINLLNGIPDKSDFYCPACQSPVRLKNGRVMRPHFAHVALQDCKFYSENESAEHLNLKAELYQSLSQTES
VEIEKVIPEPEQIADLLVNHNLALEVQCSRLSEARLCERTQAYQANGYQVLWLLGEKLWLDRRLSNLHKQFLYFSQNMGF
HLWELDINRRELRLKYLIYEDIFGKVYYQTRSCSFDGNIMTFLQLPYAKQTLTSYPVHQRRQVGLAIQKQLLARNPRWLR
QQELAYSQGRNLIAQSDADFFPQVRLPQCSRGFCQINQDVSHFSAAFFQYYQKQKDKEIQTLYPPAFYDKMK

Nucleotide

• Length: 939 bp

>NTDB_id=207451 CO204_RS07250 WP_002261897.1 1424899..1425837(-) (coiA) [Streptococcus mutans strain LAR01]
ATGTTAGTTGCAAGGGATAAAAATGGAAAGTTGATTAATCTTCTGAATGGTATTCCTGACAAAAGTGATTTTTATTGTCC
TGCCTGCCAATCACCTGTACGTCTCAAAAACGGCAGGGTTATGCGTCCGCATTTTGCCCATGTTGCTTTGCAAGACTGCA
AATTTTACAGTGAAAATGAGTCCGCTGAACACCTAAACTTGAAAGCAGAACTCTATCAGTCATTATCTCAGACGGAAAGT
GTTGAGATCGAAAAAGTCATACCAGAACCTGAACAAATCGCAGACTTATTAGTTAATCATAACCTAGCATTAGAAGTTCA
GTGTTCTCGCTTGTCCGAAGCTCGTCTGTGTGAGCGAACGCAGGCCTATCAGGCCAATGGTTATCAGGTACTGTGGCTGC
TTGGGGAGAAACTCTGGTTGGATAGGCGTTTATCCAACTTGCACAAACAATTTCTTTACTTTTCACAAAATATGGGCTTT
CATCTTTGGGAATTAGATATTAATAGGCGTGAGTTGCGACTTAAGTACTTGATTTATGAAGATATTTTTGGCAAAGTCTA
TTATCAAACGAGGTCTTGTTCTTTTGATGGTAATATCATGACCTTTTTACAATTGCCCTATGCTAAGCAAACCTTGACTT
CTTATCCTGTTCACCAGCGCAGGCAGGTTGGTTTAGCCATTCAAAAACAACTGCTAGCACGCAATCCGCGTTGGCTGCGT
CAGCAAGAACTTGCTTATTCACAGGGGCGTAATCTGATAGCACAATCAGATGCTGATTTTTTCCCGCAGGTAAGGTTACC
GCAATGTTCAAGAGGCTTTTGTCAAATCAATCAGGATGTATCTCATTTTAGCGCAGCTTTTTTTCAATATTATCAAAAGC
AAAAAGACAAAGAAATTCAAACACTGTATCCGCCAGCCTTTTATGATAAAATGAAATAA

Domains

Predicted by InterProScan.

• Competence protein CoiA-like family (CoiA_nuc) (1-263)

3D structure

• AlphaFold DB: Q8DV62

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus mitis NCTC 12261	47.249	99.038	0.468
coiA	Streptococcus pneumoniae Rx1	46.278	99.038	0.458
coiA	Streptococcus pneumoniae D39	46.278	99.038	0.458
coiA	Streptococcus pneumoniae R6	46.278	99.038	0.458
coiA	Streptococcus pneumoniae TIGR4	45.955	99.038	0.455
coiA	Lactococcus lactis subsp. cremoris KW2	39.385	100	0.41