Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BSR19_RS06165 Genome accession   NZ_CP018187
Coordinates   1249283..1250698 (-) Length   471 a.a.
NCBI ID   WP_156246788.1    Uniprot ID   A0AB37DAU4
Organism   Streptococcus salivarius strain ICDC2     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1244283..1255698
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR19_RS06135 (BSR19_06210) - 1244912..1245310 (-) 399 WP_002891126.1 cytidine deaminase -
  BSR19_RS06140 (BSR19_06215) deoC 1245297..1245959 (-) 663 WP_156246785.1 deoxyribose-phosphate aldolase -
  BSR19_RS06145 (BSR19_06220) - 1245994..1247271 (-) 1278 WP_156246786.1 pyrimidine-nucleoside phosphorylase -
  BSR19_RS06150 (BSR19_06225) - 1247268..1247858 (-) 591 WP_073686336.1 class I SAM-dependent methyltransferase -
  BSR19_RS06155 (BSR19_06230) coaA 1247972..1248892 (+) 921 WP_156246787.1 type I pantothenate kinase -
  BSR19_RS06160 (BSR19_06235) rpsT 1248962..1249198 (+) 237 WP_037597891.1 30S ribosomal protein S20 -
  BSR19_RS06165 (BSR19_06240) ciaH 1249283..1250698 (-) 1416 WP_156246788.1 sensor histidine kinase Regulator
  BSR19_RS06170 (BSR19_06245) ciaR 1250688..1251362 (-) 675 WP_049546057.1 response regulator transcription factor Regulator
  BSR19_RS06175 (BSR19_06250) - 1251561..1253231 (-) 1671 WP_002891135.1 formate--tetrahydrofolate ligase -
  BSR19_RS06180 (BSR19_06255) - 1253425..1254108 (+) 684 WP_156246789.1 phosphopantothenate--cysteine ligase -
  BSR19_RS06185 (BSR19_06260) coaC 1254101..1254646 (+) 546 WP_156246790.1 phosphopantothenoylcysteine decarboxylase -
  BSR19_RS06190 (BSR19_06265) - 1254675..1255247 (+) 573 WP_156246791.1 ECF transporter S component -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53491.26 Da        Isoelectric Point: 8.7681

>NTDB_id=206853 BSR19_RS06165 WP_156246788.1 1249283..1250698(-) (ciaH) [Streptococcus salivarius strain ICDC2]
MLTKFFNYLFRRIKSEGFKSFIHFFATFSGIFLVMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKGSTDETPDSSGSKKESKKKSKMEDAPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVIFSVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVLALKGTIVVKDNHPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=206853 BSR19_RS06165 WP_156246788.1 1249283..1250698(-) (ciaH) [Streptococcus salivarius strain ICDC2]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGAAGGATTTAAGTCTTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTGTCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCAAATGTGGATTCTA
GTCTGAAAATGGCAGCAACTAAGACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATCTACCAAGCCTATGATACTAAAGGGTCGACAGATGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAATCTAAGAAGAAATCAAAGATGGAAGATGCCCCTCACGATTTATCTGTTGCGGCGAATACCAGTGTCT
TAGTGCTTGATAAGAATGGAAAAGTCCTCAATGTCGTTGACAAATTTTCTAGCTTATCCAATTTACCAATAGATAAAAAT
AACATTGATGTTATCAGCAAGGGAAGCGCTCAGAATTATTTCGATCAAACCGAAAAGTATCGCCTGATTACTGAAAAAGT
AGATAATAGTCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTCAAGCTCATTGTCATCATGATGAGTTTCTTCTGGCTCCTATCTGTTGCGGCTAGTATGTATTTGGCCAAGTGGTCA
AGACGTCCTATCCAGGAAAGTCTGGAGAAGCAGAAGGCATTTGTTGAAAATGCCAGTCACGAGTTACGGACACCGCTTGC
TGTGATTCAAAACCGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTTTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGTAATATGCGTCTGTTGACGACAAATCTCTTGAACTTGGCTCGTCGTGACGATGGTATTAAGCCG
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAATTATGCCATGATTGCTGAAGAAAACGAGAAAGG
ATTTACGGCCCAAAACCAAGTTAGCCGTCCTATTCAGACTGATAAAACGCTACTGAAGCAGCTAATGACGATTTTATTTG
ATAATGCTATTAAGTATACAGAAGATGATGGACATGTTATCTTTTCGGTTCGCACTAATGACCGACATCTTTATATTTCG
GTAGCTGATAATGGTCCTGGTATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTAGATAAGGCTAG
AACCAGACAAAAAGGTGGGTTTGGACTGGGCTTATCACTAGCGCAACAAATTGTTTTAGCTCTTAAAGGAACAATTGTTG
TCAAGGACAATCATCCGAAGGGGACTATTTTTGAAGTTAAAATCACTGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.304

97.665

0.55
  ciaH Streptococcus pneumoniae Rx1

50

98.514

0.493
  ciaH Streptococcus pneumoniae D39

50

98.514

0.493
  ciaH Streptococcus pneumoniae R6

50

98.514

0.493
  ciaH Streptococcus pneumoniae TIGR4

50

98.514

0.493

Multiple sequence alignment