Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   BSR14_RS04070 Genome accession   NZ_CP018186
Coordinates   935955..937370 (+) Length   471 a.a.
NCBI ID   WP_156209674.1    Uniprot ID   -
Organism   Streptococcus salivarius strain ICDC1     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 930955..942370
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BSR14_RS04045 (BSR14_04100) - 931405..931977 (-) 573 WP_013990461.1 ECF transporter S component -
  BSR14_RS04050 (BSR14_04105) coaC 932006..932551 (-) 546 WP_004182014.1 phosphopantothenoylcysteine decarboxylase -
  BSR14_RS04055 (BSR14_04110) - 932544..933227 (-) 684 WP_156209672.1 phosphopantothenate--cysteine ligase -
  BSR14_RS04060 (BSR14_04115) - 933422..935092 (+) 1671 WP_073687144.1 formate--tetrahydrofolate ligase -
  BSR14_RS04065 (BSR14_04120) ciaR 935291..935965 (+) 675 WP_049546057.1 response regulator transcription factor Regulator
  BSR14_RS04070 (BSR14_04125) ciaH 935955..937370 (+) 1416 WP_156209674.1 sensor histidine kinase Regulator
  BSR14_RS04075 (BSR14_04130) rpsT 937456..937692 (-) 237 WP_004182129.1 30S ribosomal protein S20 -
  BSR14_RS04080 (BSR14_04135) coaA 937762..938682 (-) 921 WP_156209676.1 type I pantothenate kinase -
  BSR14_RS04085 (BSR14_04140) - 938795..939385 (+) 591 WP_156209678.1 class I SAM-dependent methyltransferase -
  BSR14_RS04090 (BSR14_04145) - 939382..940659 (+) 1278 WP_014634600.1 pyrimidine-nucleoside phosphorylase -
  BSR14_RS04095 (BSR14_04150) deoC 940693..941337 (+) 645 WP_014634599.1 deoxyribose-phosphate aldolase -
  BSR14_RS04100 (BSR14_04155) - 941342..941740 (+) 399 WP_156209680.1 cytidine deaminase -

Sequence

Protein


Download         Length: 471 a.a.        Molecular weight: 53534.31 Da        Isoelectric Point: 8.7661

>NTDB_id=206783 BSR14_RS04070 WP_156209674.1 935955..937370(+) (ciaH) [Streptococcus salivarius strain ICDC1]
MLTKFFNYLFRRIKSDGFKSFIHFFATFSGIFLIMTVMILQILSYGVYSNVDSSLKMAATKTNSYLEMEMLKRELFLTSE
VDQNNTTTIYQAYDTKESTAETPDSSGSKKEPKKKSKIEDTPHDLSVAANTSVLVLDKNGKVLNVVDKFSSLSNLPIDKN
NIDVISKGSAQNYFDQTEKYRLITEKVDNSLYPDAKYLVIAINTTQLEEATERYVKLIVIMMSFFWLLSVAASMYLAKWS
RRPIQESLEKQKAFVENASHELRTPLAVIQNRLEVLFRKPESTILDNSENIASSLDEVRNMRLLTTNLLNLARRDDGIKP
EIETLEPAFFDTVFTNYAMIAEENEKGFTAQNQVSRPIQTDKTLLKQLMTILFDNAIKYTEDDGHVTFTVRTNDRHLYIS
VADNGPGISDSDKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIVIALKGTIVVKDNQPKGTIFEVKITGV

Nucleotide


Download         Length: 1416 bp        

>NTDB_id=206783 BSR14_RS04070 WP_156209674.1 935955..937370(+) (ciaH) [Streptococcus salivarius strain ICDC1]
ATGCTGACTAAATTTTTCAATTATCTCTTTAGGAGAATCAAGTCAGACGGATTTAAGTCGTTCATTCATTTCTTTGCCAC
TTTTTCTGGTATTTTCCTTATCATGACTGTCATGATTTTGCAGATTCTGAGTTACGGCGTTTATTCCAATGTGGACTCTA
GTCTGAAAATGGCAGCCACTAAAACCAATTCTTATTTAGAAATGGAAATGCTAAAACGGGAACTTTTTCTGACTTCTGAG
GTAGATCAAAATAATACGACAACCATTTACCAAGCCTATGATACTAAAGAGTCGACAGCTGAAACACCTGACTCGAGTGG
CTCTAAAAAAGAACCTAAGAAGAAATCAAAAATTGAAGATACCCCTCACGATTTATCTGTTGCGGCAAATACTAGTGTCT
TGGTACTTGATAAGAATGGAAAAGTCCTTAATGTCGTTGATAAATTTTCAAGCTTATCCAATTTACCAATAGACAAAAAT
AACATTGATGTTATCAGCAAGGGAAGTGCTCAGAATTATTTCGATCAAACGGAAAAGTACCGTCTGATTACTGAAAAAGT
AGATAATAGCCTCTATCCTGATGCTAAGTACCTTGTTATTGCGATTAATACAACTCAATTGGAAGAAGCCACTGAACGTT
ATGTTAAGCTAATTGTCATCATGATGAGTTTCTTCTGGCTTTTATCTGTTGCGGCTAGTATGTATTTGGCTAAGTGGTCA
AGACGTCCTATCCAGGAAAGCTTGGAGAAGCAGAAGGCTTTTGTTGAAAATGCTAGCCATGAGTTACGGACACCGCTTGC
TGTGATTCAAAACAGATTAGAAGTTCTTTTCCGCAAGCCTGAGAGCACCATTCTAGATAATTCAGAGAATATTGCTTCAA
GTCTTGATGAAGTACGCAACATGCGTCTTTTGACGACTAATCTTTTGAACTTGGCTCGTCGTGACGATGGTATTAAACCA
GAAATCGAAACCTTAGAACCTGCTTTCTTTGATACAGTATTTACCAACTATGCCATGATTGCAGAAGAAAATGAGAAAGG
TTTCACGGCTCAAAACCAAGTTAGTCGTCCAATCCAAACTGATAAAACGTTATTGAAACAGTTAATGACCATCTTATTTG
ATAATGCTATTAAATATACGGAAGATGATGGACATGTTACCTTTACTGTTCGCACTAATGACCGCCATCTTTATATTTCT
GTAGCTGATAATGGTCCTGGAATATCAGATAGTGATAAGAAAAAAATCTTTGATCGCTTTTATCGCGTGGATAAGGCAAG
AACCAGACAAAAAGGTGGGTTTGGACTTGGCTTATCCCTAGCGCAACAAATTGTTATAGCCCTTAAAGGAACAATTGTTG
TTAAAGATAATCAACCAAAGGGAACGATTTTTGAAGTTAAAATCACCGGAGTTTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(361-468)

His Kinase A (phospho-acceptor) domain (HisKA)

(252-317)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.739

97.665

0.554
  ciaH Streptococcus pneumoniae Rx1

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae D39

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae R6

50.216

98.514

0.495
  ciaH Streptococcus pneumoniae TIGR4

50.216

98.514

0.495

Multiple sequence alignment