Detailed information    

insolico Bioinformatically predicted

Overview

Name   cclA/cilC   Type   Machinery gene
Locus tag   BMJ42_RS09630 Genome accession   NZ_CP018136
Coordinates   1752326..1752985 (+) Length   219 a.a.
NCBI ID   WP_000565027.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain SP49     
Function   processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1747326..1757985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BMJ42_RS09610 (BMJ42_01823) - 1747963..1748859 (-) 897 WP_000825669.1 PEP phosphonomutase -
  BMJ42_RS09615 (BMJ42_01824) - 1748862..1750124 (-) 1263 WP_073177278.1 PTS sugar transporter subunit IIC -
  BMJ42_RS09620 (BMJ42_01825) - 1750404..1751582 (+) 1179 WP_000175875.1 ROK family transcriptional regulator -
  BMJ42_RS09625 (BMJ42_01826) - 1751810..1752256 (-) 447 WP_000155408.1 GNAT family N-acetyltransferase -
  BMJ42_RS09630 (BMJ42_01827) cclA/cilC 1752326..1752985 (+) 660 WP_000565027.1 prepilin peptidase Machinery gene
  BMJ42_RS09635 (BMJ42_01828) trpA 1752957..1753733 (-) 777 WP_001126993.1 tryptophan synthase subunit alpha -
  BMJ42_RS09640 (BMJ42_01829) trpB 1753726..1754949 (-) 1224 WP_000331298.1 tryptophan synthase subunit beta -
  BMJ42_RS09645 (BMJ42_01830) - 1754927..1755526 (-) 600 WP_000169872.1 phosphoribosylanthranilate isomerase -
  BMJ42_RS09650 (BMJ42_01831) trpC 1755513..1756280 (-) 768 WP_000076545.1 indole-3-glycerol phosphate synthase TrpC -
  BMJ42_RS09655 (BMJ42_01832) trpD 1756277..1757281 (-) 1005 WP_000658684.1 anthranilate phosphoribosyltransferase -
  BMJ42_RS09660 (BMJ42_01833) - 1757292..1757858 (-) 567 WP_000601921.1 aminodeoxychorismate/anthranilate synthase component II -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24855.00 Da        Isoelectric Point: 7.2564

>NTDB_id=206072 BMJ42_RS09630 WP_000565027.1 1752326..1752985(+) (cclA/cilC) [Streptococcus pneumoniae strain SP49]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSVSHCDSCQTRLRPLDLIPILSQVFNRFCCRYCKVRYPVWYALFELGLG
LLFLLYSWELLSLGQVVLITAGLTLGIYDFHHQEYPLLVWMTFHLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide


Download         Length: 660 bp        

>NTDB_id=206072 BMJ42_RS09630 WP_000565027.1 1752326..1752985(+) (cclA/cilC) [Streptococcus pneumoniae strain SP49]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGTCAGTCACTGCGATTCCTGTCAGACTCGCTTGCGTCCCTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTTGCTGTCGCTACTGCAAGGTCCGCTATCCTGTCTGGTATGCCCTCTTTGAACTAGGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGAGTTGCTTTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGGAATATCCCTTACTGGTCTGGATGACTTTCCACCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTT
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTTTGA

Domains

Predicted by InterproScan.

Bacterial Peptidase A24 N-terminal domain (A24_N_bact)

(8-89)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cclA/cilC Streptococcus pneumoniae Rx1

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae D39

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae R6

97.26

100

0.973
  cclA/cilC Streptococcus pneumoniae TIGR4

96.804

100

0.968
  cclA/cilC Streptococcus mitis SK321

91.781

100

0.918
  cclA/cilC Streptococcus mitis NCTC 12261

85.845

100

0.858

Multiple sequence alignment