Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SMA_1742 Genome accession   HE613569
Coordinates   1689900..1690592 (-) Length   230 a.a.
NCBI ID   CCF03033.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1684900..1695592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_1738 dnaI 1685673..1686575 (-) 903 CCF03029.1 Helicase loader DnaI -
  SMA_1739 - 1686586..1687746 (-) 1161 CCF03030.1 Helicase loader DnaB -
  SMA_1740 nrdR 1687730..1688227 (-) 498 CCF03031.1 Ribonucleotide reductase transcriptional regulator NrdR -
  SMA_1741 - 1688416..1689900 (-) 1485 CCF03032.1 Transmembrane histidine kinase CsrS -
  SMA_1742 covR 1689900..1690592 (-) 693 CCF03033.1 Response regulator CsrR Regulator
  SMA_1743 - 1690825..1691361 (-) 537 CCF03034.1 COG1399 protein in cluster with ribosomal protein L32p, Firmicutes subfamily -
  SMA_1744 htpX 1691486..1692388 (-) 903 CCF03035.1 Heat shock protein HtpX -
  SMA_1745 lemA 1692515..1693066 (-) 552 CCF03036.1 LemA protein -
  SMA_1746 - 1693374..1694108 (+) 735 CCF03037.1 Methyltransferase GidB -
  SMA_1747 ktrB 1694175..1695548 (+) 1374 CCF03038.1 Potassium uptake protein, integral membrane component, KtrB -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26458.35 Da        Isoelectric Point: 4.8614

>NTDB_id=20364 SMA_1742 CCF03033.1 1689900..1690592(-) (covR) [Streptococcus macedonicus ACA-DC 198]
MSKKILIIEDEKNLARFVSLELQHEGYSVVVENNGRLGLQTALDDDFDLILLDLMLPDMDGFEITRRLRLGKETSIIMMT
ARDSIMDVVAGLDRGADDYIVKPFAIEELLARVRAVFRRQDVESKREQDSRGKEGLLGLRLNPQNRSAVRGDDEISLTKR
EYDLLSVLLSNVNRVMTREELLSSVWRYDTDIETNVVDVYIRYLRGKVDIPGKESYIQTVRGMGYIIREK

Nucleotide


Download         Length: 693 bp        

>NTDB_id=20364 SMA_1742 CCF03033.1 1689900..1690592(-) (covR) [Streptococcus macedonicus ACA-DC 198]
ATGAGTAAAAAGATTTTAATTATTGAAGATGAAAAAAATCTTGCACGTTTTGTATCTTTAGAGTTGCAACATGAAGGTTA
TTCAGTAGTAGTAGAAAATAATGGACGACTTGGCCTACAAACAGCTCTAGATGATGATTTTGATTTAATTTTGTTAGACT
TGATGCTTCCAGATATGGATGGTTTTGAAATTACACGCCGTCTTCGATTAGGAAAAGAGACTTCTATTATTATGATGACA
GCTCGTGATTCAATTATGGATGTTGTTGCTGGGCTTGATCGTGGTGCAGATGACTATATTGTTAAACCATTTGCAATTGA
AGAATTGTTAGCTCGTGTCCGTGCTGTTTTTCGTCGTCAAGATGTTGAATCTAAGCGTGAACAAGATAGTCGAGGAAAAG
AAGGGCTACTTGGACTACGCTTAAACCCTCAAAATCGTTCTGCTGTTCGAGGTGATGATGAAATTTCACTTACAAAACGT
GAATATGATTTGCTAAGTGTTCTTTTATCAAATGTTAATCGTGTAATGACACGTGAAGAATTATTGTCTAGTGTTTGGAG
ATATGATACAGATATTGAGACAAATGTTGTTGATGTTTATATCCGTTACCTTCGCGGAAAAGTCGATATTCCAGGTAAAG
AATCTTACATTCAAACAGTTCGTGGAATGGGATACATTATTCGAGAAAAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

74.348

100

0.743
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.755

99.565

0.635
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

42.174

100

0.422

Multiple sequence alignment