Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SMA_0469 Genome accession   HE613569
Coordinates   480739..482040 (+) Length   433 a.a.
NCBI ID   CCF01760.1    Uniprot ID   -
Organism   Streptococcus macedonicus ACA-DC 198     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 475739..487040
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMA_0464 - 476384..477028 (+) 645 CCF01755.1 Two component transcriptional regulator VraR -
  SMA_0465 ppiB 477147..478547 (+) 1401 CCF01756.1 Streptococcal lipoprotein rotamase A; Peptidyl-prolyl cis-trans isomerase -
  SMA_0466 yugI 478547..478903 (+) 357 CCF01757.1 General stress protein 13 -
  SMA_0467 cysK 479023..479952 (-) 930 CCF01758.1 Cysteine synthase -
  SMA_0468 yvyE 480056..480682 (-) 627 CCF01759.1 Protein co-occurring with transport systems (COG1739) -
  SMA_0469 comFA/cflA 480739..482040 (+) 1302 CCF01760.1 ComF operon protein A, DNA transporter ATPase Machinery gene
  SMA_0470 comFC/cflB 482037..482699 (+) 663 CCF01761.1 ComF operon protein C Machinery gene
  SMA_0471 yhbH 482775..483323 (+) 549 CCF01762.1 Ribosomal subunit interface protein -
  SMA_0472 - 483379..483546 (-) 168 CCF01763.1 Hypothetical protein -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49166.35 Da        Isoelectric Point: 9.9437

>NTDB_id=20341 SMA_0469 CCF01760.1 480739..482040(+) (comFA/cflA) [Streptococcus macedonicus ACA-DC 198]
MDKLDNYYGRLFTQAQLSDALKKQTKQLPAMTKLNHHYVCNRCGSQVSLQNKLQTNVFYCRICLVFGRNTSNGHLYYFPQ
KCFSKKNSLIWKGKLTPYQDDVSKGMLEGIDAKKDLLIHAVTGAGKTEMIYQSVSKIIDDGGCVCLASPRIDVCLELYKR
LSRDFSCPITLLHGDSESYKRAPLIIATTHQLLKFYQAFDLLIIDEVDAFPFVDNAVLYHAVDKATKPNGTKIFLTATST
DELDKKVKTGTLTKLHLARRFHANPLVVPQKIWLSGILSNMQKKKIPQKLINLLKKQRQTRYPLLIFFPNIEQGEAFTQI
LQTYFPEEQIAFVSSKTENRLEIVEKFRKQELSILVTTTILERGVTFPCVDVFVVLANHRLYTKSALVQISGRVGRAAER
PTGELLFLHDGSTKEMRKAITEIKAMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=20341 SMA_0469 CCF01760.1 480739..482040(+) (comFA/cflA) [Streptococcus macedonicus ACA-DC 198]
ATGGATAAACTGGATAATTATTATGGAAGACTATTTACACAAGCTCAACTTTCGGATGCCTTAAAAAAACAGACTAAACA
GTTACCAGCAATGACAAAATTAAATCATCATTATGTTTGCAATCGTTGTGGTAGTCAAGTATCTTTACAAAACAAACTTC
AAACAAACGTTTTTTATTGTCGAATTTGCCTTGTTTTTGGAAGAAATACGAGTAATGGACATCTCTATTATTTTCCACAA
AAATGTTTTTCTAAAAAAAATTCTCTTATTTGGAAAGGAAAATTGACTCCTTACCAAGATGACGTTTCAAAAGGGATGTT
AGAAGGTATTGATGCTAAGAAAGATCTACTTATTCATGCTGTTACAGGTGCTGGAAAAACAGAAATGATTTACCAATCTG
TATCCAAAATAATTGATGACGGTGGTTGTGTTTGCCTAGCAAGTCCGCGAATTGATGTTTGTCTGGAACTTTATAAACGC
TTGTCACGTGATTTTTCGTGTCCGATTACATTGCTTCATGGAGATTCTGAGTCCTACAAACGTGCCCCTTTAATCATTGC
CACAACACATCAACTTTTAAAATTTTACCAAGCTTTTGATTTGTTAATTATTGATGAAGTTGATGCCTTTCCATTTGTGG
ATAATGCCGTGCTTTACCATGCTGTTGATAAAGCTACCAAACCTAATGGAACCAAGATTTTTTTAACAGCGACATCAACA
GATGAATTAGATAAAAAAGTAAAAACAGGAACTCTGACCAAATTGCACCTTGCTCGACGCTTTCATGCCAATCCATTAGT
TGTGCCACAAAAAATCTGGTTGTCTGGCATTTTATCCAATATGCAAAAGAAGAAAATTCCCCAGAAATTAATAAATCTTC
TGAAAAAACAACGTCAAACCCGCTATCCTTTGCTAATCTTCTTCCCAAACATCGAACAAGGAGAAGCCTTTACTCAAATT
TTACAAACTTACTTTCCAGAAGAACAAATCGCTTTTGTGTCTAGTAAAACAGAAAATCGCTTAGAAATTGTAGAAAAATT
TAGGAAACAAGAACTTTCTATTTTGGTTACAACAACCATTTTAGAACGTGGTGTCACTTTCCCATGCGTAGATGTTTTTG
TAGTGCTTGCCAATCATAGATTATATACCAAAAGCGCGCTAGTTCAGATTTCAGGGCGAGTTGGGAGAGCAGCAGAGCGT
CCAACAGGAGAACTGTTATTCTTGCATGACGGTAGCACTAAAGAAATGAGAAAAGCTATTACTGAAATTAAAGCGATGAA
TAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(287-397)

DEAD/DEAH box helicase (DEAD)

(96-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae TIGR4

59.719

98.614

0.589
  comFA/cflA Streptococcus pneumoniae Rx1

59.719

98.614

0.589
  comFA/cflA Streptococcus pneumoniae D39

59.719

98.614

0.589
  comFA/cflA Streptococcus pneumoniae R6

59.719

98.614

0.589
  comFA/cflA Streptococcus mitis NCTC 12261

59.485

98.614

0.587
  comFA/cflA Streptococcus mitis SK321

58.782

98.614

0.58
  comFA Lactococcus lactis subsp. cremoris KW2

50.238

96.998

0.487
  comFA Latilactobacillus sakei subsp. sakei 23K

38.283

99.538

0.381

Multiple sequence alignment