Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   BKM67_RS02245 Genome accession   NZ_CP017667
Coordinates   451426..452718 (+) Length   430 a.a.
NCBI ID   WP_105183766.1    Uniprot ID   -
Organism   Streptococcus suis strain 1081     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 446426..457718
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM67_RS02220 (BKM67_02195) - 447231..447872 (+) 642 WP_105183767.1 response regulator transcription factor -
  BKM67_RS02225 (BKM67_02200) - 447922..449322 (+) 1401 WP_032510942.1 Cof-type HAD-IIB family hydrolase -
  BKM67_RS02230 (BKM67_02205) - 449324..449695 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  BKM67_RS02235 (BKM67_02210) cysK 449721..450647 (-) 927 WP_002937015.1 cysteine synthase A -
  BKM67_RS02240 (BKM67_02215) - 450737..451369 (-) 633 WP_015646510.1 YigZ family protein -
  BKM67_RS02245 (BKM67_02220) comFA/cflA 451426..452718 (+) 1293 WP_105183766.1 DEAD/DEAH box helicase Machinery gene
  BKM67_RS02250 (BKM67_02225) comFC/cflB 452711..453376 (+) 666 WP_105120746.1 ComF family protein Machinery gene
  BKM67_RS02255 (BKM67_02230) raiA 453453..453995 (+) 543 WP_014637536.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 49004.65 Da        Isoelectric Point: 8.9024

>NTDB_id=201348 BKM67_RS02245 WP_105183766.1 451426..452718(+) (comFA/cflA) [Streptococcus suis strain 1081]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKMNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRMGKLSRLSLPRRFHGNPLVVPQKVWFSKFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLFTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTEAIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=201348 BKM67_RS02245 WP_105183766.1 451426..452718(+) (comFA/cflA) [Streptococcus suis strain 1081]
ATGAAAGAATTAGAAAATTATTACGGTAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAATGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTACGGTCAGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCGACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATCTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCCTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GACTTTTCAGTTCCAATTAGTTTACTGCATGGAGAGTCTGAACCCTATTTCCGAACCCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAATGGGCAAACTAAGCCGTCTTAGTTTGCCAAGGCGCTTTCATGGCAACCCACTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAAATTCGATGATACCCTAAAGAAAAATAGACTAGTTCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATAGTTGAAGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTGACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTTCACAGCGTCAAGTCTTGTTCAGATTGCAGGCCGGGTCGGCAGGAGTATGGAACGTCCGACTGGT
TTACTCCAGTTTTATCATGAGGGAAGTACAGAAGCCATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGTTATGTCTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(289-393)

Type III restriction enzyme, res subunit (ResIII)

(91-235)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.517

100

0.677
  comFA/cflA Streptococcus pneumoniae Rx1

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae D39

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae R6

66.821

100

0.67
  comFA/cflA Streptococcus pneumoniae TIGR4

66.821

100

0.67
  comFA/cflA Streptococcus mitis SK321

66.357

100

0.665
  comFA Lactococcus lactis subsp. cremoris KW2

53.431

94.884

0.507
  comFA Latilactobacillus sakei subsp. sakei 23K

37.731

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.831

96.512

0.365

Multiple sequence alignment