Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SDD27957_10325 Genome accession   CM001076
Coordinates   1953294..1954034 (-) Length   246 a.a.
NCBI ID   EFY03648.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1948294..1959034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_10295 - 1949193..1949897 (-) 705 EFY03642.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  SDD27957_10300 - 1950017..1950196 (-) 180 EFY03643.1 hypothetical protein -
  SDD27957_10305 rpmH 1950228..1950362 (-) 135 EFY03644.1 50S ribosomal protein L34 -
  SDD27957_10310 - 1950676..1951590 (-) 915 EFY03645.1 jag protein -
  SDD27957_10315 - 1951602..1952411 (-) 810 EFY03646.1 hypothetical protein -
  SDD27957_10320 rnpA 1952395..1952754 (-) 360 EFY03647.1 ribonuclease P -
  SDD27957_10325 comE/blpR 1953294..1954034 (-) 741 EFY03648.1 Response regulator FasA Regulator
  SDD27957_10330 - 1954038..1955321 (-) 1284 EFY03649.1 Putative histidine kinase -
  SDD27957_10335 - 1955322..1956665 (-) 1344 EFY03650.1 Putative histidine kinase -
  SDD27957_10340 gltX 1957278..1958726 (-) 1449 EFY03651.1 glutamyl-tRNA synthetase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28968.27 Da        Isoelectric Point: 4.8691

>NTDB_id=20097 SDD27957_10325 EFY03648.1 1953294..1954034(-) (comE/blpR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MMNIFILEDDFIQQTRIESVVADILEEAKFPCNQLEVFANPHKLFESIQERGDHQLYFLDIEIGDEARRGLELAADIRQK
DPNAVIVFVTTHSEFAPISFKYKVSALDFIDKAVDKEQFRDQIEECIRYTYEMMSSRESEDMFLFETPQTRLKLPYKDIL
YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQLLYFDNGDSCMVSRLKMKCLFE
KWEALH

Nucleotide


Download         Length: 741 bp        

>NTDB_id=20097 SDD27957_10325 EFY03648.1 1953294..1954034(-) (comE/blpR) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGATGAATATTTTTATTCTTGAAGATGATTTTATTCAACAGACACGTATTGAATCTGTAGTGGCAGACATTTTGGAAGA
GGCTAAATTCCCTTGTAATCAGCTAGAAGTGTTTGCCAATCCTCATAAATTATTTGAAAGCATTCAAGAAAGAGGCGACC
ATCAGTTATATTTTTTAGATATTGAGATTGGTGATGAGGCTCGTCGAGGACTTGAATTGGCAGCAGATATTCGACAAAAA
GACCCCAATGCAGTCATTGTGTTTGTTACCACACATTCTGAATTTGCTCCTATTTCTTTTAAATACAAAGTGTCTGCCTT
AGATTTTATTGACAAAGCAGTTGATAAAGAACAATTTAGGGATCAGATTGAAGAATGTATCCGCTATACCTATGAGATGA
TGTCTAGCCGTGAATCAGAAGATATGTTTTTATTTGAGACCCCTCAGACAAGATTGAAATTACCTTACAAAGATATCCTT
TATTTTGCCACTGCTACGACACCCCATAAGGTGTGTTTGTGGACTCAGACGGAGAGATTGGAGTTTTATGGCAATTTATC
TGAGATACAAGCCGTGGCTCCAAAACTTTTCTTATGTCATAGATCTTACTTGGTTAATCTAGATAAGGTTGTGCGTATTG
ATAAATCCAAACAGCTCCTCTATTTTGATAATGGAGATTCCTGCATGGTCTCACGCTTAAAAATGAAATGCCTTTTTGAA
AAATGGGAGGCCTTACATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

48.117

97.154

0.467
  comE/comE1 Streptococcus equinus JB1

42.857

96.748

0.415
  comE/comE2 Streptococcus equinus JB1

40.408

99.593

0.402
  comE/comE2 Streptococcus gordonii strain NCTC7865

39.113

100

0.394
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

39.113

100

0.394

Multiple sequence alignment