Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   WH25_RS03910 Genome accession   NZ_CP017295
Coordinates   819679..820980 (+) Length   433 a.a.
NCBI ID   WP_046165173.1    Uniprot ID   -
Organism   Streptococcus gordonii strain IE35     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 814679..825980
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS03885 (WH25_03885) - 815423..816055 (+) 633 WP_046165169.1 response regulator transcription factor -
  WH25_RS03890 (WH25_03890) - 816143..817546 (+) 1404 WP_046165170.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  WH25_RS03895 (WH25_03895) - 817543..817929 (+) 387 WP_012000099.1 S1 RNA-binding domain-containing protein -
  WH25_RS03900 (WH25_03900) cysK 817964..818893 (-) 930 WP_046165171.1 cysteine synthase A -
  WH25_RS03905 (WH25_03905) - 818991..819623 (-) 633 WP_046165172.1 YigZ family protein -
  WH25_RS03910 (WH25_03910) comFA/cflA 819679..820980 (+) 1302 WP_046165173.1 DEAD/DEAH box helicase Machinery gene
  WH25_RS03915 (WH25_03915) comFC/cflB 820977..821642 (+) 666 WP_046165174.1 ComF family protein Machinery gene
  WH25_RS03920 (WH25_03920) hpf 821727..822269 (+) 543 WP_012000104.1 ribosome hibernation-promoting factor, HPF/YfiA family -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49575.54 Da        Isoelectric Point: 8.2050

>NTDB_id=197408 WH25_RS03910 WP_046165173.1 819679..820980(+) (comFA/cflA) [Streptococcus gordonii strain IE35]
MLELQDCLGRIFTKEQLPPELLKKAKRLSSIFEKKGELFCSRCYSQIDKERYLLPIGAYYCRECILLGRVSSDEDLYFFP
QESFPFISSLKWLGQLTEYQERVSKGLLEGVQNKQDTLVHAVTGAGKTEMIYQVVAQVLDQGGAVCIASPRIDVCLELYR
RLKEDFSCDISLLHGESDPYSRSPLVIATTHQLLKFYQAFDLLIVDEVDAFPYVDNPVLYHAVEQAVKNEGTTIFLTATS
TDELDKKVQKGILKRLSLPRRFHGNPLILPQKIWLYDLNKDLQREKLPAKLVKYLRKQRKTKFPLLIFASEIKKGQEIKQ
VLQKYFPEENVGFVASTTENRLEIVQDFRDKKISILVTTTILERGVTFPCVDVIVLEANHRLFTRSALVQIGGRVGRSME
RPTGDLLFFHDGTNIQIEKAINEIKAMNREAGL

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=197408 WH25_RS03910 WP_046165173.1 819679..820980(+) (comFA/cflA) [Streptococcus gordonii strain IE35]
ATGTTAGAATTGCAAGATTGTTTAGGGCGAATTTTTACTAAAGAACAGTTACCTCCTGAACTACTTAAGAAAGCTAAAAG
ACTATCATCAATTTTTGAAAAAAAGGGAGAACTCTTTTGTTCTCGCTGCTACAGTCAGATTGATAAGGAAAGATATTTAT
TGCCAATTGGTGCATATTATTGTAGAGAATGCATTCTTCTAGGGAGAGTGAGTAGTGACGAAGATCTTTATTTTTTTCCA
CAAGAGTCTTTTCCTTTTATATCGAGTTTGAAATGGCTTGGCCAATTGACAGAATATCAGGAAAGAGTTTCTAAAGGGTT
ACTTGAAGGAGTACAAAATAAGCAGGATACTTTAGTCCACGCTGTAACTGGAGCAGGAAAAACAGAGATGATATATCAAG
TGGTTGCTCAGGTGTTAGATCAAGGAGGTGCTGTCTGTATAGCTAGTCCTCGGATAGATGTCTGTTTGGAACTTTACCGG
CGTTTAAAAGAAGATTTTTCATGTGATATTTCCCTATTGCATGGGGAGTCCGACCCCTATTCACGCAGTCCCTTAGTGAT
TGCAACAACTCATCAATTACTAAAATTTTATCAGGCATTTGATTTACTCATTGTTGATGAGGTAGATGCCTTTCCTTATG
TAGATAACCCTGTGCTCTATCACGCTGTCGAGCAAGCAGTAAAAAATGAAGGAACTACAATATTCTTAACGGCTACGTCA
ACTGATGAGCTTGATAAAAAAGTTCAAAAAGGAATTTTGAAAAGATTAAGTTTGCCAAGACGCTTTCATGGAAATCCTTT
GATTCTCCCTCAAAAAATATGGCTTTATGATCTAAATAAAGACCTCCAAAGAGAAAAACTACCAGCCAAGTTAGTCAAGT
ATCTGAGAAAACAAAGAAAAACAAAATTCCCACTCTTAATTTTTGCTTCAGAAATTAAAAAAGGGCAGGAGATAAAGCAA
GTCTTACAAAAATATTTTCCAGAAGAAAATGTAGGTTTTGTAGCCTCTACAACGGAAAATAGATTAGAAATAGTGCAAGA
TTTTCGAGATAAAAAGATAAGTATATTAGTAACAACTACAATTTTAGAAAGAGGTGTTACTTTTCCATGTGTGGATGTAA
TTGTTTTGGAGGCTAACCATCGTCTCTTTACAAGGAGTGCTTTAGTACAAATTGGCGGGCGAGTGGGAAGAAGTATGGAA
CGACCGACAGGTGACTTACTATTTTTCCATGATGGCACTAATATACAGATAGAAAAAGCAATTAATGAAATTAAAGCAAT
GAACAGAGAGGCCGGATTATGA

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(97-245)

Helicase conserved C-terminal domain (Helicase_C)

(289-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

68.925

98.845

0.681
  comFA/cflA Streptococcus pneumoniae D39

68.925

98.845

0.681
  comFA/cflA Streptococcus pneumoniae R6

68.925

98.845

0.681
  comFA/cflA Streptococcus pneumoniae TIGR4

68.925

98.845

0.681
  comFA/cflA Streptococcus mitis SK321

68.31

98.383

0.672
  comFA/cflA Streptococcus mitis NCTC 12261

68.31

98.383

0.672
  comFA Lactococcus lactis subsp. cremoris KW2

53.553

90.993

0.487
  comFA Latilactobacillus sakei subsp. sakei 23K

39.907

99.538

0.397
  comFA Bacillus subtilis subsp. subtilis str. 168

39.32

95.15

0.374

Multiple sequence alignment