Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BHS01_RS09465 Genome accession   NZ_CP017195
Coordinates   1936070..1936762 (-) Length   230 a.a.
NCBI ID   WP_109835325.1    Uniprot ID   A0A7L4WH91
Organism   Lactococcus paracarnosus strain TMW 2.1615     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1931070..1941762
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BHS01_RS09450 (BHS01_09455) - 1932474..1932815 (-) 342 WP_109835322.1 P-II family nitrogen regulator -
  BHS01_RS09455 (BHS01_09460) - 1932853..1934091 (-) 1239 WP_109835323.1 ammonium transporter -
  BHS01_RS09460 (BHS01_09465) - 1934353..1935846 (-) 1494 WP_109835324.1 HAMP domain-containing sensor histidine kinase -
  BHS01_RS09465 (BHS01_09470) covR 1936070..1936762 (-) 693 WP_109835325.1 response regulator transcription factor Regulator
  BHS01_RS09470 (BHS01_09475) gndA 1936927..1938348 (-) 1422 WP_109835326.1 NADP-dependent phosphogluconate dehydrogenase -
  BHS01_RS09475 (BHS01_09480) - 1938605..1939141 (-) 537 WP_109835327.1 YceD family protein -
  BHS01_RS09480 (BHS01_09485) - 1939357..1940292 (-) 936 WP_109835328.1 manganese-dependent inorganic pyrophosphatase -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26801.53 Da        Isoelectric Point: 5.2714

>NTDB_id=196587 BHS01_RS09465 WP_109835325.1 1936070..1936762(-) (covR) [Lactococcus paracarnosus strain TMW 2.1615]
MVKKILIIEDEKQLARFVSLELEHEGYNVVVRHDGRSGLEAAISQDWDMILLDLMLPELDGFEVARRLRNEKQTPITMMT
ARDSTMDKVAGLDIGADDYITKPFAIEELLARLRANFRRQDREIQKRKKTDGTTFRDLTINKKNRQVERGGEVIDLTKRE
YDLLTTLMKNVNDVVTREQLVQNVWGYDEGTETNVVDVYIRYLRNKLDQDGKDSYIQTVRGLGYMLRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=196587 BHS01_RS09465 WP_109835325.1 1936070..1936762(-) (covR) [Lactococcus paracarnosus strain TMW 2.1615]
ATGGTAAAAAAAATACTTATTATTGAAGATGAAAAACAATTAGCACGATTTGTGTCGCTTGAGCTTGAACATGAAGGGTA
TAATGTTGTGGTACGCCATGATGGTCGTAGCGGGCTTGAAGCAGCCATATCTCAAGATTGGGATATGATTCTCTTGGACT
TGATGTTGCCTGAATTAGATGGGTTTGAAGTTGCACGTCGTTTGCGTAATGAGAAACAAACGCCAATCACGATGATGACT
GCGCGTGATAGTACCATGGATAAAGTAGCTGGTCTTGATATTGGCGCAGATGACTACATTACAAAACCATTCGCAATTGA
AGAGTTACTCGCGCGTTTACGTGCTAATTTCCGTCGTCAAGATCGTGAAATTCAAAAGCGTAAAAAAACTGATGGCACAA
CCTTCCGTGATTTGACGATTAATAAAAAGAATCGTCAAGTAGAACGTGGCGGAGAAGTGATTGACTTGACAAAACGTGAG
TATGATTTATTGACGACACTAATGAAGAATGTCAACGATGTTGTAACACGTGAACAACTTGTTCAAAATGTATGGGGATA
TGATGAAGGAACAGAGACAAACGTTGTTGATGTTTATATTCGTTATCTACGTAACAAATTAGATCAAGATGGCAAGGATT
CATATATTCAAACCGTTCGTGGTTTAGGTTATATGTTACGTGAGAATAACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7L4WH91

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Lactococcus lactis subsp. lactis strain DGCC12653

76.106

98.261

0.748
  covR Streptococcus salivarius strain HSISS4

67.544

99.13

0.67
  micA Streptococcus pneumoniae Cp1015

43.348

100

0.439
  vicR Streptococcus mutans UA159

41.81

100

0.422

Multiple sequence alignment