Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA   Type   Machinery gene
Locus tag   LCW_RS07435 Genome accession   NZ_CP017124
Coordinates   1461350..1462681 (-) Length   443 a.a.
NCBI ID   WP_069468547.1    Uniprot ID   -
Organism   Latilactobacillus curvatus strain WiKim38     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1456350..1467681
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LCW_RS07420 (LCW_07420) secA 1457412..1459775 (-) 2364 WP_004270228.1 preprotein translocase subunit SecA -
  LCW_RS07425 (LCW_07425) hpf 1460004..1460549 (-) 546 WP_004270226.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  LCW_RS07430 (LCW_07430) comFC 1460676..1461206 (-) 531 WP_155275694.1 ComF family protein Machinery gene
  LCW_RS07435 (LCW_07435) comFA 1461350..1462681 (-) 1332 WP_069468547.1 DEAD/DEAH box helicase Machinery gene
  LCW_RS07440 (LCW_07440) - 1462741..1463403 (+) 663 WP_039099348.1 YigZ family protein -
  LCW_RS07445 (LCW_07445) - 1463428..1464516 (-) 1089 WP_004270225.1 glycosyltransferase family 4 protein -
  LCW_RS07450 (LCW_07450) hemH 1464626..1465381 (-) 756 WP_418287445.1 ferrochelatase -
  LCW_RS07455 (LCW_07455) rny 1465573..1467135 (-) 1563 WP_069468358.1 ribonuclease Y -

Sequence

Protein


Download         Length: 443 a.a.        Molecular weight: 49775.95 Da        Isoelectric Point: 9.5776

>NTDB_id=195908 LCW_RS07435 WP_069468547.1 1461350..1462681(-) (comFA) [Latilactobacillus curvatus strain WiKim38]
MAKQLAYGRQWSATQLSTVMNNYSLPQIKQRLAFQIVNQRLVCQRCGQVVKEQARLPDGRYYCAACLTFGRLVEGDQLVY
VPECNLFESIVEPLTWSGTLTPFQAQAAKQIVAVITKQQRHVLTAVTGAGKTEMLFQGIATALANGQRVCVAAPRVAVCL
ELYPRLQAAFANTPIMLMHGEQTAPYRYTPLVVCTTHQLFKFYQAFDTVIVDEVDAFPFVNNPQLEMAVKQACKPCCALI
YLTATPTVKLRHAINTGDLTGSELPIRFHGHLLPEPHCYPLFTWRRSVKRHQLPSVMRNLLRKCLQEQRLLLFVPQVRDL
EAVQQSVVRALPHITVNTVHAGDPNQLDKIAAFRAGCRDVLITTTVLERGVTFKNIAVFVLGAEHVVFTESVLVQIAGRA
GRQQEHAANPVYFFYADYTVAIQRACQQIKRQNRKGRRLQSTV

Nucleotide


Download         Length: 1332 bp        

>NTDB_id=195908 LCW_RS07435 WP_069468547.1 1461350..1462681(-) (comFA) [Latilactobacillus curvatus strain WiKim38]
ATGGCAAAACAACTTGCTTATGGTCGTCAGTGGAGTGCCACCCAATTGAGTACCGTTATGAATAATTATAGTTTACCACA
GATTAAACAGCGACTAGCGTTTCAAATAGTTAATCAGCGTCTGGTATGTCAACGGTGTGGACAAGTGGTGAAAGAGCAAG
CTCGCTTACCTGATGGTCGGTATTATTGTGCTGCTTGCTTGACCTTTGGGCGGTTAGTGGAAGGGGATCAGTTGGTTTAC
GTGCCTGAATGCAATCTGTTTGAGTCGATCGTAGAACCGCTAACTTGGTCGGGGACACTAACCCCTTTTCAAGCACAAGC
CGCAAAGCAGATTGTTGCGGTCATTACCAAGCAACAACGCCATGTCTTAACTGCAGTGACCGGTGCTGGTAAAACTGAGA
TGTTATTTCAAGGCATTGCGACGGCTTTAGCTAATGGGCAGCGTGTGTGTGTTGCTGCGCCGCGGGTGGCGGTTTGTTTA
GAACTCTATCCGCGCTTGCAAGCAGCGTTTGCTAACACACCAATCATGCTGATGCATGGGGAACAGACTGCGCCTTACCG
GTATACGCCGTTAGTTGTTTGTACAACCCATCAGTTATTTAAGTTTTATCAGGCATTTGACACTGTCATTGTCGATGAGG
TTGATGCGTTCCCATTTGTCAATAATCCCCAGCTTGAGATGGCTGTTAAACAGGCGTGTAAGCCATGCTGTGCATTGATC
TATCTGACGGCGACACCAACTGTAAAGTTGCGCCATGCGATTAATACAGGGGATTTAACGGGTAGTGAGCTACCAATTCG
CTTTCATGGTCACTTATTACCTGAACCGCATTGCTATCCCTTGTTTACGTGGCGGCGTTCAGTTAAACGGCATCAGTTAC
CATCCGTGATGCGCAACTTACTCAGGAAGTGTCTTCAAGAACAACGCTTATTATTATTTGTGCCACAGGTAAGGGATTTA
GAGGCGGTTCAGCAGAGCGTTGTTCGGGCATTGCCACACATTACAGTGAACACGGTACATGCTGGCGATCCTAATCAATT
AGACAAGATAGCGGCCTTTAGAGCAGGATGCAGGGACGTGCTGATTACGACGACAGTTCTAGAACGAGGCGTAACGTTTA
AAAATATTGCAGTGTTTGTTCTTGGTGCAGAACACGTGGTCTTCACTGAATCAGTGCTTGTACAGATTGCTGGCCGAGCC
GGACGACAGCAAGAGCATGCTGCCAATCCGGTTTATTTTTTCTACGCGGATTACACGGTCGCTATTCAGCGTGCGTGTCA
ACAAATTAAACGACAAAATCGAAAAGGACGGCGATTACAATCCACTGTTTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(100-247)

Helicase conserved C-terminal domain (Helicase_C)

(297-403)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA Latilactobacillus sakei subsp. sakei 23K

65.682

99.323

0.652
  comFA/cflA Streptococcus mitis NCTC 12261

40.796

90.745

0.37
  comFA/cflA Streptococcus pneumoniae TIGR4

40.594

91.196

0.37
  comFA/cflA Streptococcus pneumoniae Rx1

40.347

91.196

0.368
  comFA/cflA Streptococcus pneumoniae D39

40.347

91.196

0.368
  comFA/cflA Streptococcus pneumoniae R6

40.347

91.196

0.368
  comFA/cflA Streptococcus mitis SK321

40.099

91.196

0.366
  comFA Bacillus subtilis subsp. subtilis str. 168

38.554

93.679

0.361

Multiple sequence alignment