Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   A7J08_RS00360 Genome accession   NZ_CP017088
Coordinates   61152..62051 (+) Length   299 a.a.
NCBI ID   WP_053867370.1    Uniprot ID   A0A3Q8B755
Organism   Streptococcus suis strain SRD478     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 62675..65480 61152..62051 flank 624


Gene organization within MGE regions


Location: 61152..65480
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS00360 (A7J08_00355) comR 61152..62051 (+) 900 WP_053867370.1 transcriptional regulator Regulator
  A7J08_RS00365 (A7J08_00365) - 62675..63964 (+) 1290 Protein_53 IS4 family transposase -
  A7J08_RS00370 - 64190..65480 (+) 1291 Protein_54 IS4 family transposase -

Sequence

Protein


Download         Length: 299 a.a.        Molecular weight: 35449.35 Da        Isoelectric Point: 4.6492

>NTDB_id=195372 A7J08_RS00360 WP_053867370.1 61152..62051(+) (comR) [Streptococcus suis strain SRD478]
MNDKEFGQRVRQLRESVSMTREQFCDDELELSVRQLTRIEAGSSKPTFSKIQYIATRLGMGLYELMPDYVSLPERYSKLK
FDVLRTPTYGNEDLAEKRDAMMTEIYDDYYDELPEEEKIAIDAIQSRIDTLESGTAGFGKEILEDYFEQIFRKRKYELND
LLIVRLHLEYVRLSSCDSEIFRQFLKIIEHLHEQINIINSNDLFVLRDTLLSCVNILGSKKYYEPIPKIFDSVDKIIQST
QDFQKKPIVSVLKWKYALFVDKDRDEAEKHYLDAVLFAKLIENRELEQKIEEDWRVDNQ

Nucleotide


Download         Length: 900 bp        

>NTDB_id=195372 A7J08_RS00360 WP_053867370.1 61152..62051(+) (comR) [Streptococcus suis strain SRD478]
ATGAACGATAAGGAATTTGGACAGCGTGTACGTCAATTACGAGAATCTGTTAGCATGACACGTGAACAGTTTTGTGACGA
TGAACTGGAACTCTCTGTGCGCCAATTAACTCGTATTGAAGCAGGTTCTTCCAAGCCGACTTTTTCAAAGATTCAGTATA
TTGCAACTCGTTTAGGTATGGGACTTTACGAGCTTATGCCAGATTACGTATCCTTACCCGAAAGATATTCCAAGCTGAAG
TTTGATGTGCTTCGCACCCCAACTTATGGTAATGAAGATTTGGCGGAAAAGCGAGATGCCATGATGACAGAAATCTATGA
CGATTATTATGATGAATTGCCTGAGGAGGAGAAGATAGCAATAGATGCGATTCAATCACGAATTGATACTTTAGAGTCAG
GTACAGCAGGCTTTGGAAAAGAGATACTGGAAGACTACTTTGAACAAATTTTTCGCAAACGAAAGTATGAATTGAATGAT
TTGTTGATTGTTAGGCTCCATCTTGAATATGTTAGGTTATCTAGCTGTGATTCAGAAATATTTAGACAGTTTTTGAAAAT
TATAGAGCATTTACATGAGCAAATCAATATCATCAATTCAAATGATTTATTTGTTCTAAGAGATACATTATTATCTTGTG
TAAACATTTTGGGAAGTAAAAAATATTACGAACCAATACCAAAGATATTTGACAGTGTAGATAAGATTATACAGTCGACA
CAAGATTTTCAGAAAAAGCCCATTGTTAGTGTATTAAAATGGAAATATGCACTTTTTGTGGATAAGGATCGGGATGAGGC
TGAAAAGCATTATCTAGATGCGGTGCTATTTGCAAAATTGATAGAAAATAGAGAGTTAGAACAAAAGATAGAAGAAGATT
GGAGAGTTGACAATCAATAA

Domains

Predicted by InterproScan.

ComR tetratricopeptide (ComR_TPR)

(73-294)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3Q8B755

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus suis P1/7

99.331

100

0.993
  comR Streptococcus suis 05ZYH33

99.331

100

0.993
  comR Streptococcus suis D9

61.462

100

0.619
  comR Streptococcus mutans UA159

43.813

100

0.438
  comR Streptococcus pyogenes MGAS315

37.374

99.331

0.371

Multiple sequence alignment