Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CCZ36_RS04170 Genome accession   NZ_CP021707
Coordinates   940433..941053 (+) Length   206 a.a.
NCBI ID   WP_069737351.1    Uniprot ID   A0ABQ2TIN2
Organism   Streptomyces sp. S063     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 935433..946053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCZ36_RS04150 - 936742..937380 (-) 639 WP_069744554.1 vitamin K epoxide reductase family protein -
  CCZ36_RS04155 - 937517..938374 (+) 858 WP_069737348.1 ABC transporter ATP-binding protein -
  CCZ36_RS04160 - 938371..939192 (+) 822 WP_128817045.1 ABC transporter permease -
  CCZ36_RS04165 - 939150..940433 (+) 1284 WP_069737350.1 sensor histidine kinase -
  CCZ36_RS04170 vraR 940433..941053 (+) 621 WP_069737351.1 response regulator transcription factor Regulator
  CCZ36_RS04175 hisS 941118..942380 (-) 1263 WP_128817046.1 histidine--tRNA ligase -
  CCZ36_RS04180 - 942398..943087 (-) 690 WP_128817047.1 MBL fold metallo-hydrolase -
  CCZ36_RS04185 - 943245..944036 (+) 792 WP_069737354.1 peptidylprolyl isomerase -
  CCZ36_RS04190 - 944250..945479 (+) 1230 WP_128817048.1 DUF349 domain-containing protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21996.46 Da        Isoelectric Point: 5.7792

>NTDB_id=195084 CCZ36_RS04170 WP_069737351.1 940433..941053(+) (vraR) [Streptomyces sp. S063]
MIRVLLADDHPVVREGLRGMLDAEPDLTVVAEASSGPRAEALCAELLPDIVLMDLRMPGGGGVESIRRIRAAGLPCRVVV
LTTYDSDSDILRAVEAGASGYLLKDLGRAELADAIRAAARGETVLAPTVATRLVDQLREAPEVPRLSERETQVLRLVAEG
CTNAEIGRRLFIGESTVKTHLLRVFGKLGVSDRTAAVTGAMRHGLL

Nucleotide


Download         Length: 621 bp        

>NTDB_id=195084 CCZ36_RS04170 WP_069737351.1 940433..941053(+) (vraR) [Streptomyces sp. S063]
ATGATCCGAGTCCTGCTGGCCGACGACCACCCCGTCGTACGGGAGGGGCTGCGCGGGATGCTGGACGCCGAGCCGGACCT
GACCGTGGTGGCCGAGGCGTCCAGCGGTCCGCGTGCCGAGGCGCTCTGCGCGGAGCTGCTGCCGGACATCGTGCTGATGG
ACCTGCGAATGCCGGGCGGCGGGGGCGTCGAGTCGATCCGCCGGATCAGGGCGGCCGGGCTGCCGTGCCGGGTCGTCGTG
CTGACCACGTACGACAGCGACAGCGACATCCTGCGCGCGGTGGAGGCCGGCGCGTCCGGCTATCTGCTCAAGGACCTGGG
CCGGGCGGAGCTGGCGGACGCGATCCGGGCCGCGGCCCGGGGCGAGACGGTGCTGGCCCCGACGGTGGCGACCCGGCTGG
TGGACCAGTTGCGCGAAGCGCCGGAGGTGCCCCGGCTCTCGGAGCGCGAGACGCAGGTGCTGCGGCTGGTGGCGGAGGGG
TGCACCAACGCGGAGATCGGGCGGCGGCTGTTCATCGGCGAGTCGACGGTGAAGACCCATCTGCTGCGGGTCTTCGGCAA
GCTGGGCGTCAGCGACCGGACCGCCGCGGTGACGGGGGCGATGCGCCACGGGCTGCTGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.32

100

0.393
  letA Legionella pneumophila str. Paris

37.799

100

0.383
  letA Legionella pneumophila strain ERS1305867

37.799

100

0.383
  degU Bacillus subtilis subsp. subtilis str. 168

34.529

100

0.374